(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 3ik6 | HCZ | Hydrochlorothiazide (DB00999) | Hydrochlorothiazide is a thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. | GLUTAMATE RECEPTOR 2 (Rattus norvegicus) | NA | ||
| 3ilu | HFZ | Hydroflumethiazide (DB00774) | Hydroflumethiazide is a thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. | GLUTAMATE RECEPTOR 2 (Rattus norvegicus) | NA | ||
| 3lsf | PZI | Piracetam (DB09210) | Piracetam is a nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer. | GLUTAMATE RECEPTOR 2 (Rattus norvegicus) | NA | ||
| 3tkd | CYZ | Cyclothiazide (DB00606) | As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides... | GLUTAMATE RECEPTOR 2 (Rattus norvegicus) | NA | ||
| 5l1f | 6ZP | Perampanel (DB08883) | Perampanel is a non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy. | GLUTAMATE RECEPTOR 2 (Rattus norvegicus) | ANF_receptorLig_chanLig_chan-Glu_bd | ||
| 7ocf | CYZ | Cyclothiazide (DB00606) | As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides... | ISOFORM FLIP OF GLUTAMATE RECEPTOR 1;ISOFORM FLIP OF GLUTAMATE RECEPTOR 2 (NA) | NA | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |