Ligand ID: 6ZP

Drugbank ID:
Perampanel
(DB08883)

Indication:
Perampanel is a non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.

LIST OF BINDING INTERFACES for query 'DB08883'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
5L1F_A_6ZPA902	5l1f	6ZP	Perampanel (DB08883)	Rattus norvegicus	GLUTAMATE RECEPTOR 2	ANF_receptor Lig_chan Lig_chan-Glu_bd	14	LYS A 511 PRO A 512 SER A 516 PHE A 517 LEU A 518 ASP A 519 PRO A 520 TYR A 616 ASN A 619 LEU A 620 PHE A 623 SER B 785 SER A 788 ASN A 791	6ZP A 902		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["5L1F_A_6ZPA902","5l1f","6ZP","Perampanel (DB08883)","Rattus norvegicus","GLUTAMATE RECEPTOR 2","ANF_receptor;Lig_chan;Lig_chan-Glu_bd",14,"LYS A 511;PRO A 512;SER A 516;PHE A 517;LEU A 518;ASP A 519;PRO A 520;TYR A 616;ASN A 619;LEU A 620;PHE A 623;SER B 785;SER A 788;ASN A 791","6ZP A 902\r"]]