
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
4v04 | 0LI | Ponatinib (DB08901) | Ponatinib is a kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML). | FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B (Homo sapiens) | PK_Tyr_Ser-Thr | ||
5ew8 | 5SF | Erdafitinib (DB12147) | Erdafitinib is a fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma. | FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens) | PK_Tyr_Ser-Thr | ||
5zv2 | LEV | Lenvatinib (DB09078) | Lenvatinib is a receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. | FIBROBLAST GROWTH FACTOR RECEPTOR 1 (Homo sapiens) | PK_Tyr_Ser-Thr | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |