Ligand ID: 5SF

Drugbank ID:
Erdafitinib
(DB12147)


Indication:
Erdafitinib is a fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma.


LIST OF BINDING INTERFACES for query 'DB12147'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
5EW8_A_5SFA8035ew8 5SFErdafitinib
(DB12147)
Homo sapiens FIBROBLAST GROWTH FACTOR RECEPTOR 1 PK_Tyr_Ser-Thr 25LEU A 484
GLY A 485
VAL A 492
ALA A 512
LYS A 514
LEU A 528
GLU A 531
MET A 535
ILE A 545
VAL A 559
VAL A 561
GLU A 562
TYR A 563
ALA A 564
SER A 565
LYS A 566
GLY A 567
GLU A 571
ARG A 627
ASN A 628
LEU A 630
ILE A 639
ALA A 640
ASP A 641
PHE A 642
5SF A 803
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details