
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
1gs4 | ZK5 | Fludrocortisone (DB00687) | Fludrocortisone is a mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome. | ANDROGEN RECEPTOR (Homo sapiens) | Hormone_recep | ||
2am9 | TES | Testosterone (DB00624) | Testosterone is a hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. | ANDROGEN RECEPTOR (Homo sapiens) | Hormone_recep | ||
2oz7 | CA4 | Cyproterone acetate (DB04839) | Cyproterone acetate is a steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer | ANDROGEN RECEPTOR (Homo sapiens) | Hormone_recep | ||
2piv | T3 | Liothyronine (DB00279) | Liothyronine is a thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism. | ANDROGEN RECEPTOR (Homo sapiens) | Hormone_recep | ||
2pix | FLF | Flufenamic acid (DB02266) | Flufenamic acid is an analgesic drug used to relieve pain associated with rheumatoid diseases. | ANDROGEN RECEPTOR (Homo sapiens) | Hormone_recep | ||
3zqt | 30Z | Masoprocol (DB00179) | A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in... | ANDROGEN RECEPTOR (Escherichia coli) | Hormone_recep | ||
4k7a | MXD | Minoxidil (DB00350) | Minoxidil is an antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage. | ANDROGEN RECEPTOR (Homo sapiens) | Hormone_recep | ||
4oha | HFT | Flutamide (DB00499) | Flutamide is an antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma. | ANDROGEN RECEPTOR (Homo sapiens;synthetic construct) | Hormone_recep | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |