Results: Ligand

Ligand ID: T3

Drugbank ID:
Liothyronine
(DB00279)

Indication:
Liothyronine is a thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism.

LIST OF BINDING INTERFACES for query 'DB00279'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1SN5_C_T3C601	1sn5	T3	Liothyronine (DB00279)	Sparus aurata	TRANSTHYRETIN	Transthyretin	17	MET C 13 LYS C 15 LYS A 15 LEU C 17 LEU A 17 GLU A 54 GLU C 54 THR C 106 THR A 106 ALA A 108 ALA C 108 LEU A 109 LEU C 109 LEU A 110 LEU C 110 VAL A 121 VAL C 121	T3 C 601
2H79_A_T3A1	2h79	T3	Liothyronine (DB00279)	Homo sapiens	THRA PROTEIN	NA	23	PHE A 215 PHE A 218 ILE A 221 ILE A 222 ALA A 225 ARG A 228 MET A 256 MET A 259 SER A 260 ARG A 262 ALA A 263 ARG A 266 THR A 275 LEU A 276 SER A 277 GLY A 278 LEU A 287 GLY A 290 GLY A 291 LEU A 292 ILE A 299 HIS A 381 PHE A 401	T3 A 1
2PIV_A_T3A933	2piv	T3	Liothyronine (DB00279)	Homo sapiens	ANDROGEN RECEPTOR	Hormone_recep	12	PRO A 671 ILE A 672 PHE A 673 PRO A 723 GLY A 724 ASN A 727 GLU A 829 LEU A 830 ASN A 833 TYR A 834 GLU A 837 ARG A 840	T3 A 933
3GWS_X_T3X500	3gws	T3	Liothyronine (DB00279)	Homo sapiens	THYROID HORMONE RECEPTOR BETA	Hormone_recep	23	PHE X 269 PHE X 272 ILE X 275 ILE X 276 ALA X 279 ARG X 282 MET X 310 MET X 313 SER X 314 ARG X 316 ALA X 317 ARG X 320 THR X 329 LEU X 330 ASN X 331 LEU X 341 GLY X 344 GLY X 345 LEU X 346 ILE X 353 HIS X 435 MET X 442 PHE X 455	T3 X 500
3VKX_A_T3A301	3vkx	T3	Liothyronine (DB00279)	Homo sapiens	PROLIFERATING CELL NUCLEAR ANTIGEN	PCNA_C PCNA_N	15	MET A 40 VAL A 45 SER A 46 LEU A 47 LEU A 126 GLY A 127 ILE A 128 PRO A 129 GLN A 131 TYR A 133 VAL A 233 PRO A 234 TYR A 250 LEU A 251 ALA A 252	T3 A 301
4BVA_A_T3A1314	4bva	T3	Liothyronine (DB00279)	Mus musculus	THIOMORPHOLINE-CARBOXYLATE DEHYDROGENASE	OCD_Mu_crystall	16	ARG A 47 VAL A 49 PHE A 58 LEU A 59 GLY A 60 LYS A 75 VAL A 77 PHE A 79 HIS A 91 THR A 115 SER A 228 ARG A 229 PRO A 230 TRP A 232 GLU A 256 LEU A 292	T3 A1314
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1SN5_C_T3C601","1sn5","T3","Liothyronine (DB00279)","Sparus aurata","TRANSTHYRETIN","Transthyretin",17,"MET C  13;LYS C  15;LYS A  15;LEU C  17;LEU A  17;GLU A  54;GLU C  54;THR C 106;THR A 106;ALA A 108;ALA C 108;LEU A 109;LEU C 109;LEU A 110;LEU C 110;VAL A 121;VAL C 121"," T3 C 601\r"],["2H79_A_T3A1","2h79","T3","Liothyronine (DB00279)","Homo sapiens","THRA PROTEIN","NA",23,"PHE A 215;PHE A 218;ILE A 221;ILE A 222;ALA A 225;ARG A 228;MET A 256;MET A 259;SER A 260;ARG A 262;ALA A 263;ARG A 266;THR A 275;LEU A 276;SER A 277;GLY A 278;LEU A 287;GLY A 290;GLY A 291;LEU A 292;ILE A 299;HIS A 381;PHE A 401"," T3 A   1\r"],["2PIV_A_T3A933","2piv","T3","Liothyronine (DB00279)","Homo sapiens","ANDROGEN RECEPTOR","Hormone_recep",12,"PRO A 671;ILE A 672;PHE A 673;PRO A 723;GLY A 724;ASN A 727;GLU A 829;LEU A 830;ASN A 833;TYR A 834;GLU A 837;ARG A 840"," T3 A 933\r"],["3GWS_X_T3X500","3gws","T3","Liothyronine (DB00279)","Homo sapiens","THYROID HORMONE RECEPTOR BETA","Hormone_recep",23,"PHE X 269;PHE X 272;ILE X 275;ILE X 276;ALA X 279;ARG X 282;MET X 310;MET X 313;SER X 314;ARG X 316;ALA X 317;ARG X 320;THR X 329;LEU X 330;ASN X 331;LEU X 341;GLY X 344;GLY X 345;LEU X 346;ILE X 353;HIS X 435;MET X 442;PHE X 455"," T3 X 500\r"],["3VKX_A_T3A301","3vkx","T3","Liothyronine (DB00279)","Homo sapiens","PROLIFERATING CELL NUCLEAR ANTIGEN","PCNA_C;PCNA_N",15,"MET A  40;VAL A  45;SER A  46;LEU A  47;LEU A 126;GLY A 127;ILE A 128;PRO A 129;GLN A 131;TYR A 133;VAL A 233;PRO A 234;TYR A 250;LEU A 251;ALA A 252"," T3 A 301\r"],["4BVA_A_T3A1314","4bva","T3","Liothyronine (DB00279)","Mus musculus","THIOMORPHOLINE-CARBOXYLATE DEHYDROGENASE","OCD_Mu_crystall",16,"ARG A  47;VAL A  49;PHE A  58;LEU A  59;GLY A  60;LYS A  75;VAL A  77;PHE A  79;HIS A  91;THR A 115;SER A 228;ARG A 229;PRO A 230;TRP A 232;GLU A 256;LEU A 292"," T3 A1314\r"]]