Potential binding sites containing ten residues derived from binding site similarity searches

DrReposER ID Hit Organism /
Macromolecule		 Interface HETATM RMSD Dali Z-score Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1 6eot DIPEPTIDYL
PEPTIDASE 8

Homo sapiens 		ARG A 160
GLU A 275
GLU A 276
TYR A 669
VAL A 781
TYR A 787
TYR A 791
ASN A 835
VAL A 836
HIS A 865		 None
 0.63A 1x70A-6eotA:
undetectable		 1x70A-6eotA:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1 6eot DIPEPTIDYL
PEPTIDASE 8

Homo sapiens 		ARG A 160
GLU A 275
GLU A 276
SER A 755
VAL A 781
TYR A 787
TYR A 791
ASN A 835
VAL A 836
HIS A 865		 None
 0.62A 1x70B-6eotA:
undetectable		 1x70B-6eotA:
7.26