Potential binding sites containing twelve residues derived from binding site similarity searches

DrReposER ID Hit Organism /
Macromolecule		 Interface HETATM RMSD Dali Z-score Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_N_PCFN606_0 4pd4 CYTOCHROME B

Saccharomyces
cerevisiae 		TRP C 29
PHE C 94
MET C 95
MET C 97
ALA C 98
TYR C 102
TYR C 103
THR C 317
PHE C 327
VAL C 330
VAL C 334
TYR C 359		 3PH C4006 (-3.6A)
3PH C4006 ( 4.8A)
None
3PH C4006 ( 4.1A)
3PH C4006 (-3.6A)
3PH C4006 (-3.3A)
3PH C4006 (-4.9A)
3PH C4006 (-3.3A)
3PH C4006 ( 4.9A)
3PH C4006 ( 4.4A)
None
None
 0.38A 6hu9N-4pd4C:
undetectable		 6hu9N-4pd4C:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0 2aaz THYMIDYLATE
SYNTHASE

Cryptococcus
neoformans 		PHE A 72
ILE A 100
TRP A 101
ASN A 104
LEU A 184
ASP A 219
LEU A 222
GLY A 223
PHE A 226
ASN A 227
TYR A 259
MET A 315		 CB3 A2351 (-3.9A)
CB3 A2351 (-3.6A)
CB3 A2351 (-3.7A)
CB3 A2351 (-3.7A)
None
CB3 A2351 ( 3.6A)
CB3 A2351 (-4.1A)
CB3 A2351 ( 3.2A)
CB3 A2351 (-3.8A)
UMP A 350 ( 3.2A)
CB3 A2351 ( 4.3A)
CB3 A2351 (-3.4A)
 0.56A 6r2eA-2aazA:
undetectable		 6r2eA-2aazA:
56.34