Ligand ID: POD


Drugbank ID:
DB01179
(Podofilox)


Indication:
For treatment of external genital warts (Condyloma acuminatum).

Get human targets for POD in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'POD' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
VAL B1176
LEU C 945
ALA C 944
LYS C 947
LEU C 948
1.54A16.13
16.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 115
CYH C  32
LEU C  55
LEU C  56
VAL C  22
1.56A18.72

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA B 125
LEU B 128
ALA A 400
VAL A 398
ALA A 382
1.64A18.72

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 115
CYH C  32
LEU C  55
LEU C  56
VAL C  22
1.57A18.72

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
VAL A 128
LEU A 707
ALA A 706
LEU A 708
ALA A  46
1.67A20.51

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.55A
NHE  B 203 (-4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  49
CYH B 143
LEU B 127
ALA B 124
VAL B 151
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  49
CYH B 143
LEU B 127
ALA B 124
VAL B 151
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.49A
NHE  B 203 (-4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.51A
NHE  B 203 (-4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.57A
NHE  B 203 (-4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w02 NSP3
(SARS-CoV-2)		5 / 12
LEU A  12
LYS B  11
LEU A  10
VAL A 155
ALA A 154
1.37A17.19
18.79
None
None
None
APR  A 201 ( 4.6A)
APR  A 201 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w4b NSP9
(SARS-CoV-2)		5 / 12
CYH A  15
ALA A  29
LEU A  46
ALA A  44
VAL A  42
1.39A14.21
19.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w4h NSP16
(SARS-CoV-2)		5 / 12
LEU A6961
ALA A6960
ASN A7083
ALA A7056
ALA A6858
1.37A20.39
20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6961
ALA A6960
ASN A7083
ALA A7056
ALA A6858
1.41A16.59
17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w61 NSP10
(SARS-CoV-2)		5 / 12
LEU B4328
ALA B4277
LYS B4281
VAL B4274
ALA B4273
1.75A17.21
15.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6961
ALA A6960
ASN A7083
ALA A7056
ALA A6858
1.40A16.59
17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.52A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.65A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 124
LEU B 123
VAL B  49
ALA B  38
1.78A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
ALA B 112
VAL B  95
ALA B  38
1.79A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  77
LEU B 126
ALA B 129
LEU B 127
VAL B  49
1.72A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 153
ALA A 124
LEU A 123
VAL A  49
ALA A  38
1.72A15.32
20.74
None
None
None
AMP  A 201 ( 3.7A)
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.41A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.54A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
LEU B  93
ASN B  37
ALA B  89
1.77A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A 100
LEU A 153
LEU A 127
ALA A  38
VAL A  49
1.80A15.32
20.74
None
None
None
AMP  A 201 ( 3.9A)
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
LEU B  93
ASN B  37
ALA B  27
1.67A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A 165
LEU B  12
LEU B  10
VAL B 155
ALA B 154
1.50A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  89
1.75A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B  88
ALA B  27
ASN B   4
VAL B  36
ALA B 124
1.80A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 124
LEU B 123
VAL B  49
ALA B  38
1.76A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.51A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  77
LEU A 126
ALA A 129
LEU A 127
VAL A  49
1.72A15.32
20.74
None
AMP  A 201 ( 4.4A)
AMP  A 201 ( 3.4A)
None
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.41A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.68A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 153
ALA A 124
LEU A 123
VAL A  49
ALA A  38
1.71A15.32
20.74
None
None
None
AMP  A 201 ( 3.7A)
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  77
LEU B 126
ALA B 129
LEU B 127
VAL B  49
1.74A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.43A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
ALA A 112
VAL A  95
ALA A  38
1.78A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  77
ALA B 129
LEU B 127
ALA B  38
VAL B  49
1.80A15.32
20.74
None
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 154
LYS B  19
ASN B  20
VAL B  49
1.66A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
ALA B 112
VAL B  95
ALA B  38
1.78A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
LEU B  93
ASN B  37
ALA B  89
1.77A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  35
ALA B 112
LEU B 127
ALA B  39
VAL B  41
1.56A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  35
LEU A 109
ALA A 112
LEU A 127
ALA A  38
1.79A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  34
LEU B 109
ALA B 112
ALA B 124
ALA B  38
1.80A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  34
LEU A 109
ALA A 112
ALA A 124
ALA A  38
1.77A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.54A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
LEU B  93
ASN B  37
ALA B  27
1.65A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  27
1.64A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.57A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B  88
ALA B  27
ASN B   4
VAL B  36
ALA B 124
1.80A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A 165
LEU B  12
LEU B  10
VAL B 155
ALA B 154
1.54A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  89
1.75A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  34
LEU A 109
ALA A 112
ALA A 124
ALA A  38
1.78A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  35
LEU A 109
ALA A 112
LEU A 127
ALA A  38
1.77A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.39A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  77
LEU A 126
ALA A 129
LEU A 127
VAL A  49
1.70A15.32
20.74
None
AMP  A 201 ( 4.4A)
AMP  A 201 ( 3.4A)
None
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  77
ALA A 129
LEU A 127
ALA A  38
VAL A  49
1.79A15.32
20.74
None
AMP  A 201 ( 3.4A)
None
AMP  A 201 ( 3.9A)
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 153
ALA A 154
LYS A  19
ASN A  20
VAL A  49
1.72A15.32
20.74
None
AMP  A 201 ( 4.5A)
None
None
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.54A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
ALA A 112
VAL A  95
ALA A  38
1.80A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6802
LYS C6799
ALA C6997
VAL C6995
ALA C6832
1.66A16.37
15.84
None
None
None
None
FMT  C7111 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
VAL C7087
LEU C6961
ALA C6960
ASN C6920
VAL C7057
1.67A16.37
15.84
None
None
None
FMT  C7106 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
VAL C7087
LEU C6961
ALA C6960
ASN C6920
VAL C7057
1.72A16.37
15.84
None
None
None
FMT  C7106 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU C 125
LEU C 178
ALA C 204
VAL C 242
LYS C 182
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
CYH C 148
LEU C 152
ALA C 149
ALA C 135
ALA C 144
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
CYH A  14
ALA A  28
LEU A  45
ALA A  43
VAL A  41
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
CYH A  14
ALA A  28
LEU A  45
ALA A  43
VAL A  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.56A
None
None
None
MES  A 201 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  27
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 207
LEU A 327
ASN A 208
ALA A 293
LYS A 294
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 286
LEU A 357
ALA A 328
LEU A 326
ALA A 231
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 207
LEU A 327
ASN A 208
ALA A 293
LYS A 294
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 286
LEU A 357
ALA A 328
LEU A 326
ALA A 231
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
ALA A 260
ALA A 293
VAL A 239
LYS A 235
ALA A 231
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 286
ALA A 328
LEU A 326
VAL A 234
ALA A 231
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 286
ALA A 328
LEU A 326
VAL A 234
ALA A 231
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL A  53
LEU B 189
ALA B 126
LEU B 128
ALA B 152
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A   3
LEU A 123
ASN A   4
ALA A  89
LYS A  90
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  35
ALA B 112
LEU B 127
ALA B  39
VAL B  41
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6802
LYS A6798
ALA A6997
VAL A6995
ALA A6832
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL C  33
ALA B  86
LEU C  40
ASN C  37
VAL A  16
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 130
LEU C  13
LEU C  56
VAL C  66
ALA C  65
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL A  53
LEU B 189
ALA B 126
LEU B 128
ALA B 152
1.68A
EDO  B 302 ( 4.8A)
None
None
None
EDO  B 302 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL C  33
ALA B  86
LEU C  40
ASN C  37
VAL A  16
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 130
LEU C  13
LEU C  56
VAL C  66
ALA C  65
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL C  53
LEU D 189
ALA D 126
LEU D 128
ALA D 152
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL D 130
LEU C  13
LEU C  56
VAL C  66
ALA C  65
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL D 130
LEU C  13
LEU C  56
VAL C  66
ALA C  65
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 122
ALA D 124
LEU D  93
ASN D  37
ALA D  27
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL E  35
ALA E 112
LEU E 127
ALA E  39
VAL E  41
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL E  82
LEU E 153
ALA E 124
LEU E 122
VAL E  30
ALA E  27
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.52A
None
None
EDO  A 202 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  49
CYH C 143
LEU C 127
ALA C 124
VAL C 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 153
ALA E 154
ALA E  27
VAL E  30
LYS E  28
1.63A
None
EDO  E 205 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL E  82
LEU E 153
ALA E 124
LEU E 122
VAL E  30
ALA E  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.53A
None
None
EDO  A 202 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B   3
LEU B 123
ASN B   4
ALA B  89
LYS B  90
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B   3
LEU B 123
ASN B   4
ALA B  89
LYS B  90
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 122
ALA C 124
LEU C  93
ASN C  37
ALA C  27
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  56
ALA E  89
VAL E  35
LYS E  31
ALA E  27
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 153
ALA E 154
ALA E  27
VAL E  30
LYS E  28
1.60A
None
EDO  E 205 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  49
CYH D 143
LEU D 127
ALA D 124
VAL D 151
1.43A
EDO  D 209 (-4.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  77
LEU D 126
ALA D 129
LEU D 127
VAL D  49
1.67A
None
APR  D 201 (-4.5A)
APR  D 201 (-3.4A)
None
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  77
LEU B 126
ALA B 129
LEU B 127
VAL B  49
1.68A
None
APR  B 201 (-4.7A)
APR  B 201 (-3.6A)
None
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 153
ALA E 154
ALA E  27
VAL E  30
LYS E  28
1.58A
None
APR  E 201 (-4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 122
ALA D 124
LEU D  93
ASN D  37
ALA D  27
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  35
ALA B 112
LEU B 127
ALA B  39
VAL B  41
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL E  82
LEU E 153
ALA E 124
LEU E 122
VAL E  30
ALA E  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  56
ALA E  89
VAL E  35
LYS E  31
ALA E  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL E  82
LEU E 153
ALA E 124
LEU E 122
VAL E  30
ALA E  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 153
ALA E 154
ALA E  27
VAL E  30
LYS E  28
1.60A
None
APR  E 201 (-4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  56
ALA E  89
VAL E  35
LYS E  31
ALA E  27
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL E  35
ALA E 112
LEU E 127
ALA E  39
VAL E  41
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 122
ALA D 124
LEU D  93
ASN D  37
ALA D  27
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.59A
EDO  B 203 ( 4.6A)
None
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  35
ALA B 112
LEU B 127
ALA B  39
VAL B  41
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  77
LEU C 126
ALA C 129
LEU C 127
VAL C  49
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  27
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  49
CYH C 143
LEU C 127
ALA C 124
VAL C 151
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  77
LEU C 126
ALA C 129
LEU C 127
VAL C  49
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  49
CYH C 143
LEU C 127
ALA C 124
VAL C 151
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.58A
EDO  B 203 ( 4.6A)
None
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  49
CYH B 143
LEU B 127
ALA B 124
VAL B 151
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A   3
LEU A 123
ASN A   4
ALA A  89
LYS A  90
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 122
ALA C 124
LEU C  93
ASN C  37
ALA C  27
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 154
ALA B  27
VAL B  30
LYS B  28
1.62A
None
EDO  B 202 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 154
ALA B  27
VAL B  30
LYS B  28
1.60A
None
EDO  B 202 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A   3
LEU A 123
ASN A   4
ALA A  89
LYS A  90
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 115
CYH C  32
LEU C  55
LEU C  56
VAL C  22
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
VAL A 234
ALA A 185
LEU A 186
VAL A 128
ALA A 125
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
VAL A 234
ALA A 185
LEU A 186
VAL A 128
ALA A 125
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 115
CYH C  32
LEU C  55
LEU C  59
VAL C  22
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL C  53
LEU D 189
ALA D 125
LEU D 128
ALA D 152
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
VAL A 128
LEU A 707
ALA A 706
LEU A 708
ALA A  46
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
VAL A 128
LEU A 707
ALA A 706
LEU A 708
ALA A  46
1.60A
None