Ligand ID: EZL


Drugbank ID:
DB00311
(Ethoxzolamide)


Indication:
For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.

Get human targets for EZL in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'EZL' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
VAL B 261
THR B 225
THR B 226
1.62A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.41A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		1uj1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.52A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.37A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.43A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.50A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.55A19.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.54A23.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.58A19.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
VAL A 198
VAL A 337
VAL A 333
LEU A 308
PRO A 318
1.18A25.27
None
GOL  A1010 (-3.8A)
None
None
GOL  A1010 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 11
HIS C 227
GLU C 246
HIS C 276
LEU C 270
THR C 239
1.63A23.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2ajf ACE2
(Homo
sapiens)		5 / 11
GLU B 375
HIS B 374
ALA B 413
LEU B 370
THR B 371
1.77A18.78
 ZN  B 901 ( 3.7A)
ZN  B 901 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.62A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.63A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
GLU A 240
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.70A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.59A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 8
HIS D  14
VAL D  16
LEU D  53
ALA D  97
1.34A18.50
None
None
D10  C1099 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 8
HIS B  14
VAL B  16
LEU B  53
ALA B  97
1.36A19.70
None
None
D10  B1099 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.36A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		4 / 8
VAL L 156
LEU L 133
THR L 132
ALA L 131
1.37A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL H 184
VAL H 182
LEU H 159
TRP H 154
1.20A18.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
GLN L 186
VAL L 156
LEU L 133
THR L 132
PRO L 121
1.33A22.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		4 / 8
VAL L  47
VAL L  48
LEU L  73
THR L  74
1.35A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2duc REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
HIS B 172
GLU B 166
HIS B 163
VAL B 114
LEU B 141
1.44A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 11
HIS A  46
GLU A  65
HIS A  95
LEU A  89
THR A  58
1.68A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
VAL C  17
VAL C 156
VAL C 152
LEU C 127
PRO C 137
1.18A23.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
VAL B 206
PHE B 242
VAL B 126
LEU B 174
THR B 171
1.44A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
LEU C 200
THR C 201
ALA C 205
TRP B 107
1.34A22.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 10
HIS A   2
VAL A  74
LEU A  66
THR A  68
THR A  68
1.49A24.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 10
HIS A  70
HIS A  70
HIS A  70
LEU A  66
THR A  68
1.30A17.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 10
HIS A  70
HIS A  70
VAL A  74
LEU A  66
THR A  68
1.39A17.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 9
HIS A  70
HIS A  70
VAL A  74
LEU A  66
THR A  68
1.34A17.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 10
HIS A  70
HIS A  70
LEU A  66
THR A  68
ALA A  65
1.36A17.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 11
HIS A   2
ALA A  65
LEU A  66
THR A  68
THR A  68
1.36A17.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2gtb 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
GLU A 240
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.75A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		4 / 8
HIS B 335
LEU B 332
THR B 333
ALA A 337
1.41A17.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2k7x REPLICASE
POLYPROTEIN 1AB MAIN
PROTEASE
(SARS-COV
Sino1-11)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.35A18.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2k7x REPLICASE
POLYPROTEIN 1AB MAIN
PROTEASE
(SARS-COV
Sino1-11)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.35A18.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr)		5 / 10
VAL A  86
VAL A  62
LEU A  25
THR A  26
ALA A  33
1.37A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 8
VAL A  62
LEU A  25
THR A  26
ALA A  33
1.34A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.40A21.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.62A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.59A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
VAL A  96
LEU A  49
THR A  47
THR A  48
PRO A  50
1.57A23.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.43A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.60A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 11
HIS A 172
GLU A 166
HIS A 163
VAL A 114
ALA A   7
1.54A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.80A24.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.43A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.38A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.48A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2q6g POLYPEPTIDE CHAIN
REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 11
HIS B 163
HIS B 172
GLU B 166
ALA B  41
LEU D   5
1.74A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.61A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.36A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.55A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.42A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.34A23.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.41A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.75A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.79A23.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.72A20.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.62A20.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.50A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.58A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.43A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.38A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.55A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.46A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.52A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 164
VAL A 148
LEU A 177
THR A 175
1.37A22.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.80A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.59A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		3bgf F26G19 FAB
(Mus
musculus)		5 / 10
VAL B 121
VAL B 144
LEU B 154
THR B 153
THR B 155
1.63A26.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		3bgf F26G19 FAB
(Mus
musculus)		5 / 9
VAL B 199
VAL B 121
LEU B 179
THR B 178
ALA B 170
1.57A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		3bgf F26G19 FAB
(Mus
musculus)		5 / 10
VAL B 199
LEU B 179
THR B 178
ALA B 170
PRO B 169
1.71A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		3bgf F26G19 FAB
(Mus
musculus)		5 / 10
VAL B 121
VAL B 144
LEU B 154
THR B 153
THR B 155
1.64A26.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3bgf F26G19 FAB
(Mus
musculus)		4 / 8
VAL B 121
VAL B 144
LEU B 154
THR B 153
1.20A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3bgf F26G19 FAB
(Mus
musculus)		5 / 11
ALA H  78
THR H  58
THR H  57
PRO H  52
TRP H  47
1.67A22.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 11
GLU A 375
HIS A 374
ALA A 413
LEU A 370
THR A 371
1.68A18.89
 ZN  A 901 (-3.8A)
ZN  A 901 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
HIS B 401
VAL B 404
LEU B 558
ALA B 384
1.35A16.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.49A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.53A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.43A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3e9s NSP3
(SARSr-CoV)		5 / 12
VAL A 206
PHE A 242
VAL A 126
LEU A 174
THR A 171
1.37A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3ea8 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3ea8 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.51A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.38A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
GLU A 240
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.71A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.61A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.58A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU D 205
THR D 201
1.42A18.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.55A16.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.52A16.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.55A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
ALA A 193
LEU A 167
PRO A 168
1.77A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.52A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 172
HIS A 163
VAL A 114
ALA A 139
1.34A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.62A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS B  41
HIS B 164
VAL B 186
LEU B 167
PRO B 168
1.79A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.65A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
ALA A 194
LEU A 167
PRO A 168
1.71A22.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.58A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.62A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.35A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.68A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.39A21.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3i6k HLA, A-2
(Homo
sapiens)		4 / 8
HIS A 192
LEU A 201
THR A 200
ALA A 246
1.33A19.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS D 246
VAL D 247
LEU B 205
THR B 201
1.28A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS D 246
VAL D 247
LEU B 205
THR B 201
1.22A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.44A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.59A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.38A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.50A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.68A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.76A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.77A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.78A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.73A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.69A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.48A23.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.37A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.34A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.58A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.56A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
GLU A 240
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.79A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3scj ACE2
(Homo
sapiens)		4 / 8
HIS A 401
VAL A 404
LEU A 558
ALA A 384
1.42A16.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
HIS A 241
VAL A 485
VAL A 487
LEU A 267
1.38A16.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		3sck SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL E 498
VAL E 420
LEU E 412
ALA E 406
PRO E 450
1.60A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
HIS A 401
VAL A 404
LEU A 558
ALA A 384
1.41A16.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 11
GLU B 375
HIS B 374
ALA B 413
LEU B 370
THR B 371
1.69A18.73
 ZN  B 901 (-3.6A)
ZN  B 901 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		3scl SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL F 498
VAL F 420
LEU F 412
ALA F 406
PRO F 450
1.63A21.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.42A21.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
ALA A 194
LEU A 167
PRO A 168
1.79A21.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
VAL A 206
PHE A 242
VAL A 126
LEU A 174
THR A 171
1.49A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		4mds 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A22.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		5 / 10
HIS A 172
HIS B 172
PHE B 128
LEU B 174
THR B 171
1.59A19.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		5 / 12
VAL B 206
PHE B 242
VAL B 126
LEU B 174
THR B 171
1.38A19.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		4ow0 PAPAIN-LIKE PROTEASE
(SARS-COV
Urbani)		5 / 11
HIS A 172
HIS B 172
ALA B 177
LEU B 174
THR B 171
1.48A22.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.72A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.42A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
VAL A 206
PHE A 242
VAL A 126
LEU A 174
THR A 171
1.44A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
VAL B 206
PHE B 242
VAL B 126
LEU B 174
THR B 171
1.36A20.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
HIS B  90
VAL B 160
ALA B  40
LEU B  37
THR B  55
1.75A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL B 562
PHE B 529
VAL B 313
LEU B 538
THR B 539
1.44A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		5x29 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr-CoV)		4 / 8
VAL B  58
LEU C  31
THR C  35
ALA C  32
1.40A15.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 8
VAL C 581
LEU C 615
THR C 616
ALA C 618
0.98A10.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
VAL C 810
VAL C 804
LEU C1078
THR C1076
THR C1077
1.29A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
VAL B 581
LEU B 615
THR B 616
ALA B 618
1.34A11.33
VAL  B 581 ( 0.6A)
LEU  B 615 ( 0.6A)
THR  B 616 ( 0.8A)
ALA  B 618 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5y3e REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
VAL A 206
PHE A 242
VAL A 126
LEU A 174
THR A 171
1.48A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL B 596
VAL B 581
LEU B 615
THR B 616
ALA B 618
1.46A11.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
HIS B  70
HIS B  33
VAL B  66
LEU B 209
1.25A11.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
VAL B 596
VAL B 581
LEU B 615
THR B 616
ALA B 618
1.38A11.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
HIS C  70
HIS C  33
VAL C 254
VAL C  66
THR C  92
1.73A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL A 596
VAL A 606
VAL A 581
LEU A 615
THR A 616
1.52A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
HIS C  70
HIS C  33
VAL C 254
VAL C  66
THR C  92
1.75A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
VAL C 581
LEU C 615
THR C 616
ALA C 618
1.21A11.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6ack ACE2
(Homo
sapiens)		5 / 11
HIS D 241
ALA D 443
LEU D 444
THR D 282
TRP D 275
1.59A18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ack ACE2
(Homo
sapiens)		5 / 12
VAL D 581
VAL D 226
LEU D 520
THR D 517
THR D 519
1.39A19.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
VAL B 581
LEU B 615
THR B 616
ALA B 618
1.17A10.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
VAL A 581
LEU A 615
THR A 616
ALA A 618
1.08A10.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
VAL B 562
PHE B 529
VAL B 313
LEU B 538
THR B 539
1.50A12.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
HIS A1040
VAL A 933
VAL A 934
LEU A 930
ALA A1038
1.58A10.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
VAL B 498
VAL B 420
LEU B 412
ALA B 406
PRO B 450
1.55A10.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens)		5 / 10
HIS A 192
VAL A 189
LEU A 201
THR A 200
TRP A 274
1.65A21.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6jyt HELICASE
(SARSr-CoV)		4 / 8
HIS A 230
VAL A 181
LEU A 227
THR A 228
1.37A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6jyt HELICASE
(SARSr-CoV)		4 / 8
VAL A 356
LEU A 363
THR A 359
ALA A 362
1.18A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6jyt HELICASE
(SARSr)		5 / 10
HIS A 311
VAL A 314
LEU A 363
ALA A 362
PRO A 364
1.39A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6jyt HELICASE
(SARSr-CoV)		5 / 12
HIS A 311
VAL A 314
VAL A 305
LEU A 363
PRO A 364
1.25A18.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m0j ACE2
(Homo
sapiens)		4 / 8
HIS A 345
VAL A 343
LEU A 359
THR A 347
1.29A16.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m17 ACE2
(Homo
sapiens)		4 / 8
HIS D 345
VAL D 343
LEU D 359
THR D 347
1.27A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m17 ACE2
(Homo
sapiens)		4 / 8
HIS B 345
VAL B 343
LEU B 359
THR B 347
1.05A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		6m1d ACE2
(Homo
sapiens)		5 / 10
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.76A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		6m1d ACE2
(Homo
sapiens)		5 / 10
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.78A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		6m1d ACE2
(Homo
sapiens)		5 / 10
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.77A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m1d ACE2
(Homo
sapiens)		5 / 10
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.76A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6m1d ACE2
(Homo
sapiens)		5 / 11
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.77A15.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6m1d ACE2
(Homo
sapiens)		5 / 12
VAL D 226
VAL D 581
LEU D 520
THR D 517
THR D 519
1.37A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
HIS A 661
VAL A 642
VAL A 675
THR A 662
1.40A11.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
VAL C 581
LEU C 615
THR C 616
ALA C 618
1.28A11.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL H 198
VAL H 196
LEU H 173
TRP H 168
1.40A18.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		5 / 11
GLU L 200
VAL L 120
ALA L 117
LEU L 206
THR L 202
1.60A24.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		5 / 11
HIS H 178
VAL L 168
ALA L 149
THR L 177
PRO L 118
1.63A23.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6nus NSP12
NSP8
(SARSr-CoV)		5 / 12
VAL A 330
VAL A 398
VAL B 115
THR B 123
THR B 124
1.44A13.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6nus NSP8
(SARSr-CoV)		4 / 8
VAL B 115
LEU B 103
THR B 124
ALA B 102
1.21A23.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6vw1 ACE2
(Homo
sapiens)		4 / 8
HIS A 345
VAL A 343
LEU A 359
THR A 347
1.28A16.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6vw1 ACE2
(Homo
sapiens)		4 / 8
HIS A 401
VAL A 404
LEU A 558
ALA A 384
1.12A16.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
HIS L 198
VAL L 146
VAL L 196
LEU L 136
1.78A19.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
HIS H 200
VAL H 198
LEU H 178
ALA H 168
1.63A17.99
None
None
GOL  L 301 (-4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
VAL H 121
LEU H 124
ALA H 125
TRP H 154
1.52A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 11
HIS H 164
VAL L 163
ALA L 144
THR L 172
PRO L 113
1.66A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 11
GLU L 195
VAL L 115
ALA L 112
LEU L 201
THR L 197
1.56A19.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
VAL H 184
VAL H 182
LEU H 159
TRP H 154
1.24A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
HIS L 189
VAL L 150
PHE L 209
VAL L 132
LEU L 181
1.61A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL H 188
VAL H 186
LEU H 163
TRP H 158
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
HIS H 204
VAL H 202
LEU H 182
ALA H 172
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
GLN C   6
VAL C 110
LEU C  79
THR C  20
THR C  78
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 11
HIS H 168
VAL L 169
ALA L 150
THR L 178
PRO L 119
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 11
HIS B 168
VAL C 169
ALA C 150
THR C 178
PRO C 119
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
HIS L 195
VAL L 156
PHE L 215
VAL L 138
LEU L 187
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
HIS B 204
VAL B 202
LEU B 182
ALA B 172
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL B 188
VAL B 186
LEU B 163
TRP B 158
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 11
GLU C 201
VAL C 121
ALA C 118
LEU C 207
THR C 203
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL H 188
VAL H 186
LEU H 163
TRP H 158
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
HIS L 204
VAL L 152
VAL L 202
LEU L 181
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
HIS H 204
VAL H 202
LEU H 182
ALA H 172
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
HIS L 204
VAL L 152
VAL L 202
LEU L 142
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 11
HIS H 168
VAL L 169
ALA L 150
THR L 178
PRO L 119
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
VAL B 188
VAL B 186
LEU B 163
TRP B 158
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
HIS L 195
VAL L 156
PHE L 215
VAL L 138
LEU L 187
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
HIS H 204
VAL H 202
LEU H 182
ALA H 172
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
HIS B 204
VAL B 202
LEU B 182
ALA B 172
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 11
HIS B 168
VAL C 169
ALA C 150
THR C 178
PRO C 119
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
VAL H 188
VAL H 186
LEU H 163
TRP H 158
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
HIS C 195
VAL C 156
PHE C 215
VAL C 138
LEU C 187
1.63A
None