Ligand ID: DHI


Drugbank ID:
DB00117
(L-Histidine)


Indication:
The actions of supplemental L-histidine are entirely unclear. It may have some immunomodulatory as well as antioxidant activity. L-histidine may be indicated for use in some with rheumatoid arthritis. It is not indicated for treatment of anemia or uremia or for lowering serum cholesterol.

Get human targets for DHI in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'DHI' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.75A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  29
GLY A 120
GLY A  71
1.37A19.87
None
None
None
DMS  A 403 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PRO A  39
GLY A  29
GLY A 120
GLY A 143
1.45A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  29
GLY A 120
GLY A  71
1.45A19.87
None
None
None
DMS  A 403 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.76A12.21

None
None
ELL  D   3 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A 143
GLY A 146
GLY A  29
1.26A12.21

None
ELL  D   3 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6m0j ACE2
SPIKE RECEPTOR
BINDING DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 4
GLY E 447
TYR E 449
GLY E 496
ASP A  38
1.37A22.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m0j ACE2
SPIKE RECEPTOR
BINDING DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
GLY E 504
GLY E 502
GLY A 354
GLY A 352
0.99A19.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A 143
GLY A 146
GLY A  29
1.26A12.50

None
ELL  D   3 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.77A12.50

None
None
ELL  D   3 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		4 / 6
GLY E 496
PHE E 497
PRO E 499
LYS E 444
1.62A9.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
GLY E 504
GLY E 502
GLY B 354
GLY B 352
0.99A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 4
GLY D 354
TYR F 505
GLY F 504
ASP F 405
1.55A18.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		4 / 5
GLU E 406
PHE E 497
TYR E 508
PRO E 507
1.64A21.51
0.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 4
GLY F 447
TYR F 449
GLY F 496
ASP D  38
1.30A21.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY C  11
GLY C  15
GLY A  11
1.06A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY C  11
GLY A  11
GLY A  15
1.15A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY B  15
GLY B  11
GLY D  11
0.61A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY B  11
GLY B  15
GLY D  11
1.03A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY A  11
GLY C  11
GLY C  15
1.29A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 4
SER D 147
GLY D 146
GLY D 143
GLY D 120
1.75A12.50

None
None
3WL  D 401 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY B  15
GLY B  11
GLY D  11
0.84A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY C  11
GLY C  15
GLY A  11
1.21A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY B  11
GLY D  11
GLY D  15
1.10A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY C  11
GLY A  11
GLY A  15
1.25A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
HIS C 246
GLN C 107
THR C 243
PRO C 241
1.79A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 4
SER B 147
GLY B 146
GLY B 143
GLY B 120
1.80A12.50

None
None
3WL  B 401 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY A  11
GLY C  11
GLY C  15
1.05A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY D  11
GLY D  15
GLY B  11
1.06A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  11
GLY A  15
GLY C  11
1.06A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY C  15
GLY C  11
GLY A  11
0.71A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
HIS D 246
GLN D 107
THR D 243
PRO D 241
1.71A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY D  15
GLY D  11
GLY B  11
0.77A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY D  11
GLY B  11
GLY B  15
1.19A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 4
SER C 147
GLY C 146
GLY C 143
GLY C 120
1.77A12.50

None
None
3WL  C 401 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY D 143
GLY D 146
GLY D  29
1.23A12.50

None
3WL  D 401 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  15
GLY A  11
GLY C  11
0.82A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  15
GLY A  11
GLY C  11
0.59A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY D  11
GLY D  15
GLY B  11
1.20A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY D  11
GLY B  11
GLY B  15
1.26A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.80A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR A 113
GLY A 117
PHE A 111
1.68A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 596
PHE A 594
0.98A3.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.25A7.12

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6m71 NSP12
(SARS-CoV-2)		3 / 3
TYR A 831
PRO A 830
LEU A 829
1.53A1.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.13A7.12

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 597
PHE A 594
0.88A3.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
SER C 884
GLY C 885
GLY C 891
GLY C 889
1.54A5.04
5.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN A 317
GLN A 314
THR B 859
PRO B 862
1.55A11.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR A 266
PRO A 217
LEU A 189
1.55A0.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
SER A 111
GLY A  79
GLY A  97
0.93A16.96
17.54
None
SO4  A 201 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		4 / 4
SER B 128
GLY B  97
GLY B 133
GLY B 130
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
TYR A 152
GLY A   8
PHE A   6
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
SER B 111
GLY B  79
GLY B  97
0.97A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		4 / 4
SER A 128
GLY A  97
GLY A 133
GLY A 130
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR C 266
PRO C 217
LEU C 189
1.37A0.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR B 380
GLY B 413
PHE B 429
1.66A2.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
SER A 884
GLY A 885
GLY A 891
GLY A 889
1.50A4.56
4.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 317
GLN C 314
THR A 859
PRO A 862
1.80A11.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER A 721
GLY A1046
GLY A1044
0.98A4.56
4.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR B 612
GLY B 594
PHE B 318
1.41A2.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR B 266
PRO B 217
LEU B 189
1.40A0.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
SER A 884
GLY A 885
GLY A 891
GLY A 889
1.53A4.56
4.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER B 721
GLY B1046
GLY B1044
0.88A4.56
4.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR B 238
GLY B 239
PHE B 233
1.42A5.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
SER A 288
GLY A 247
GLY A 239
0.93A11.32
None
CIT  A 412 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 412
GLY H  97
GLY C 431
GLY C 381
1.72A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 384
GLY C 381
GLY H  97
GLY C 431
1.62A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 384
GLY H  97
GLY C 381
GLY C 431
1.23A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 412
GLY H  97
GLY C 381
GLY C 431
1.51A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 384
GLY H  95
GLY H  97
GLY C 381
1.45A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 6
PRO C 507
GLY C 404
GLY C 504
GLY C 502
1.68A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		3 / 3
SER C 494
GLY C 496
GLY C 447
1.27A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 6
PRO C 499
GLY C 446
GLY C 447
GLY C 496
1.39A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 384
GLY C 381
GLY H  97
GLY C 431
1.59A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		3 / 3
SER C 443
GLY C 447
GLY C 496
1.21A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w4h NSP16
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.86A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w4h NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
0.99A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w4h NSP16
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.40A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6w4h NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.67A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4353
GLY B4378
GLY B4380
GLY B4305
1.57A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4322
GLY B4323
GLY B4347
1.73A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
0.98A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6w61 NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A6962
GLY A7076
1.38A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.38A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6878
GLY A6875
GLY A6871
GLY A6869
1.80A15.03
SAM  A7104 (-3.9A)
None
SAM  A7104 (-4.4A)
SAM  A7104 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4323
GLY B4347
GLY B4322
1.74A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A7076
GLY A6962
1.62A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4353
GLY B4305
GLY B4380
GLY B4378
1.28A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A7076
GLY A6962
1.68A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4347
GLY B4323
GLY B4322
1.34A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A6962
GLY A7076
1.49A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6878
GLY A6869
GLY A6871
GLY A6875
1.80A15.03
SAM  A7104 (-3.9A)
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6878
GLY A6869
GLY A6871
GLY A6875
1.60A15.03
SAM  A7104 (-3.9A)
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.29A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4347
GLY B4323
GLY B4322
1.28A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.87A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.14A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4322
GLY B4323
GLY B4347
1.43A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO A 125
GLY A  51
GLY A  47
GLY A  48
1.35A18.12
18.75
None
None
None
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  51
GLY A  47
GLY A  48
GLY A  46
1.39A18.12
18.75
None
None
AMP  A 201 ( 3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.41A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  51
GLY B  46
1.77A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.22A18.12
18.75
AMP  A 201 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.36A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  48
GLY A  51
GLY A  46
1.78A18.12
18.75
None
AMP  A 201 ( 3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6w6y NSP3
(SARS-CoV-2)		3 / 3
TYR A 152
GLY A   8
PHE A   6
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 4
SER A 128
GLY A  97
GLY A 133
GLY A 130
1.74A18.12
18.75
None
None
None
AMP  A 201 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO B 125
GLY B  51
GLY B  47
GLY B  48
1.33A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  51
GLY A  47
GLY A  48
GLY A  46
1.43A18.12
18.75
None
None
AMP  A 201 ( 3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO A 125
GLY A  47
GLY A  51
GLY A  48
1.47A18.12
18.75
None
None
None
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY B  48
GLY B  46
1.53A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY B  48
GLY B  46
1.58A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.20A18.12
18.75
AMP  A 201 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.20A18.12
18.75
None
None
None
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  48
GLY B  51
1.67A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO B 125
GLY B  47
GLY B  51
GLY B  48
1.50A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO A 125
GLY A  51
GLY A  48
GLY A 130
1.46A18.12
18.75
None
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.34A18.12
18.75
None
None
AMP  A 201 ( 3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  48
GLY A  51
GLY A  46
1.71A18.12
18.75
None
AMP  A 201 ( 3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		3 / 3
SER A 111
GLY A  79
GLY A  97
0.98A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO B 125
GLY B  51
GLY B  48
GLY B 130
1.41A18.12
18.75
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  48
GLY B  47
GLY B 130
1.38A18.12
18.75
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.26A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.27A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  51
GLY B  46
1.72A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  48
GLY B  51
1.68A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.16A18.12
18.75
None
None
None
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  48
GLY B  47
GLY B 130
1.46A18.12
18.75
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6963
GLY C6962
GLY C7076
1.51A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6878
GLY C6869
GLY C6871
GLY C6875
1.64A14.55
SAM  C7105 ( 3.9A)
SAM  C7105 ( 3.8A)
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4347
GLY B4323
GLY B4322
1.36A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4347
GLY D4323
GLY D4322
1.28A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A7076
GLY A6962
1.68A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
0.99A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6w75 NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.69A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4353
GLY B4378
GLY B4380
GLY B4305
1.59A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4353
GLY D4378
GLY D4380
GLY D4305
1.54A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4353
GLY B4305
GLY B4380
GLY B4378
1.33A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6963
GLY C7076
GLY C6962
1.69A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
SER C6964
GLY C6962
GLY C7076
0.85A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 4
SER C6964
GLY C7006
GLY C6962
GLY C7076
1.36A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4322
GLY D4323
GLY D4347
1.71A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4347
GLY D4323
GLY D4322
1.35A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6962
GLY C7076
GLY C6963
1.33A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
0.97A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6963
GLY C7076
GLY C6962
1.63A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6878
GLY A6869
GLY A6871
GLY A6875
1.64A14.55
SAM  A7102 ( 3.8A)
SAM  A7102 ( 3.8A)
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6963
GLY C6962
GLY C7076
1.40A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4347
GLY B4323
GLY B4322
1.29A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4322
GLY B4323
GLY B4347
1.72A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A7076
GLY A6962
1.62A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.27A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4323
GLY D4347
GLY D4322
1.73A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4322
GLY D4323
GLY D4347
1.42A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4353
GLY D4305
GLY D4380
GLY D4378
1.29A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.12A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.84A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4323
GLY B4347
GLY B4322
1.74A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.37A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A6962
GLY A7076
1.48A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6w75 NSP10
(SARS-CoV-2)		4 / 6
ASN D4315
GLN D4318
THR D4309
PRO D4312
1.68A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4322
GLY B4323
GLY B4347
1.43A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A6962
GLY A7076
1.38A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
1.16A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
TYR C  71
PRO C 129
LEU C 132
1.73A7.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wcf NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
MES  A 202 (-3.4A)
MES  A 202 (-4.7A)
MES  A 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wcf NSP3
(SARS-CoV-2)		3 / 3
SER A 111
GLY A  79
GLY A  97
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wcf NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
MES  A 202 (-3.4A)
MES  A 202 (-4.7A)
MES  A 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wen NSP3
(SARS-CoV-2)		4 / 4
SER A 128
GLY A  97
GLY A 133
GLY A 130
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 6
GLY A 250
GLY A 251
GLY A 255
GLY A 252
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 6
GLY A 252
GLY A 251
GLY A 250
GLY A 255
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		3 / 3
SER A 315
GLY A 283
GLY A 301
0.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 6
GLY A 252
GLY A 251
GLY A 250
GLY A 255
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 4
SER A 332
GLY A 301
GLY A 337
GLY A 334
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 6
GLY A 250
GLY A 251
GLY A 255
GLY A 252
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
PRO F 309
GLY F 316
GLY E 284
GLY F 335
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR E 333
GLY E 335
PHE E 314
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ARG B 277
GLY B 287
LYS B 361
THR B 362
1.78A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR B 333
GLY B 335
PHE B 314
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
SER C6964
GLY C6962
GLY C7076
0.85A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wjt NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.84A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wjt NSP10
(SARS-CoV-2)		4 / 6
ASN D4315
GLN D4318
THR D4309
PRO D4312
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 4
SER C6964
GLY C7006
GLY C6962
GLY C7076
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
0.96A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.00A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR B 112
GLY B 116
PHE B 110
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR A 112
GLY A 116
PHE A 110
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
SER C 105
GLY C  60
GLY C 170
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 4
SER C6964
GLY C7006
GLY C6962
GLY C7076
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
0.97A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wkq NSP10
(SARS-CoV-2)		4 / 6
ASN D4315
GLN D4318
THR D4309
PRO D4312
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.84A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wkq NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
0.99A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
SER C6964
GLY C6962
GLY C7076
0.84A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
SER A 288
GLY A 247
GLY A 239
0.92A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
SER B 288
GLY B 247
GLY B 239
0.94A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR B 238
GLY B 254
PHE B 233
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR B 238
GLY B 239
PHE B 233
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR A 238
GLY A 254
PHE A 233
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR A 180
GLY A 126
PHE A 135
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR B 180
GLY B 126
PHE B 135
1.53A
None
ACT  B 408 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.74A
None
None
U5G  A 401 (-3.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.12A
APR  D 201 (-3.5A)
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.07A
APR  B 201 (-3.4A)
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  46
GLY C  47
GLY C  51
GLY C  48
1.07A
APR  C 201 (-3.9A)
APR  C 201 (-4.1A)
None
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY B  48
GLY B  51
1.17A
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
APR  B 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY B  48
GLY B  46
1.23A
None
APR  B 201 (-4.0A)
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  47
GLY C  46
GLY C  48
GLY C  51
1.17A
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.09A
APR  A 201 (-3.9A)
APR  A 201 (-4.1A)
None
APR  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  46
GLY D  47
GLY D  51
GLY D  48
1.06A
APR  D 201 (-3.8A)
APR  D 201 (-4.2A)
None
APR  D 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  47
GLY D  46
GLY D  48
GLY D  51
1.14A
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
APR  D 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  51
GLY A  47
GLY A  48
GLY A  46
1.29A
None
APR  A 201 (-4.1A)
APR  A 201 (-3.5A)
APR  A 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.10A
APR  B 201 (-3.4A)
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
TYR C 152
GLY C   8
PHE C   6
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.08A
APR  B 201 (-3.7A)
APR  B 201 (-4.0A)
None
APR  B 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  47
GLY D  46
GLY D  48
GLY D  51
1.12A
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
APR  D 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  51
GLY D  47
GLY D  48
GLY D  46
1.28A
None
APR  D 201 (-4.2A)
APR  D 201 (-3.5A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.19A
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
APR  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.11A
APR  A 201 (-3.5A)
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  51
GLY D  47
GLY D  48
GLY D  46
1.25A
None
APR  D 201 (-4.2A)
APR  D 201 (-3.5A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  51
GLY A  47
GLY A  48
GLY A  46
1.31A
None
APR  A 201 (-4.1A)
APR  A 201 (-3.5A)
APR  A 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.08A
APR  D 201 (-3.5A)
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
TYR D 152
GLY D   8
PHE D   6
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.07A
APR  A 201 (-3.5A)
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY B  48
GLY B  51
1.14A
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
APR  B 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.08A
APR  C 201 (-3.5A)
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY B  48
GLY B  46
1.26A
None
APR  B 201 (-4.0A)
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.17A
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
APR  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
SER A 111
GLY A  79
GLY A  97
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.10A
APR  B 201 (-3.7A)
APR  B 201 (-4.0A)
None
APR  B 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  46
GLY C  47
GLY C  51
GLY C  48
1.10A
APR  C 201 (-3.9A)
APR  C 201 (-4.1A)
None
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
TYR A 152
GLY A   8
PHE A   6
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  46
GLY D  47
GLY D  51
GLY D  48
1.08A
APR  D 201 (-3.8A)
APR  D 201 (-4.2A)
None
APR  D 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.11A
APR  C 201 (-3.5A)
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.12A
APR  A 201 (-3.9A)
APR  A 201 (-4.1A)
None
APR  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  47
GLY C  46
GLY C  48
GLY C  51
1.15A
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.84A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wq3 NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.68A
None
None
SO4  B4404 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PRO A 122
GLY B  11
GLY A  11
GLY A  15
0.99A12.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  29
GLY A 120
GLY A  71
1.39A19.87
None
None
None
DMS  A 406 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  29
GLY A 120
GLY A  71
1.46A19.87
None
None
None
DMS  A 406 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.77A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PRO A  39
GLY A  29
GLY A 120
GLY A 143
1.46A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLU E 406
PHE E 497
TYR E 508
PRO E 507
1.80A21.43
0.47
None
None
DMS  E 902 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO E 384
GLY H  99
GLY H 101
GLY E 381
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 494
GLY E 496
GLY E 447
1.06A
MLI  E 903 (-4.6A)
MLI  E 903 ( 4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO A 384
GLY B  99
GLY B 101
GLY A 381
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 443
GLY E 447
GLY E 496
1.13A
None
None
MLI  E 903 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
GLY E 502
TYR E 505
GLY E 504
ASP E 405
1.73A23.48
None
None
DMS  E 902 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO E 384
GLY H  99
GLY H 101
GLY E 381
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO E 412
GLY E 381
GLY E 431
GLY H 101
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLU E 406
PHE E 497
TYR E 508
PRO E 507
1.80A21.43
0.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
GLY E 496
PHE E 497
PRO E 499
LYS E 444
1.67A9.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 494
GLY E 496
GLY E 447
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 443
GLY E 447
GLY E 496
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER A 494
GLY A 496
GLY A 447
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER A 443
GLY A 447
GLY A 496
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLU E 406
PHE E 497
TYR E 508
PRO E 507
1.80A21.70
1.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO E 384
GLY H  99
GLY H 101
GLY E 381
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 443
GLY E 447
GLY E 496
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO A 384
GLY B  99
GLY B 101
GLY A 381
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 494
GLY E 496
GLY E 447
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
GLY A 502
TYR A 505
GLY A 504
ASP A 405
1.73A21.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
GLY E 502
TYR E 505
GLY E 504
ASP E 405
1.73A21.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  46
GLY B  47
GLY B  51
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  46
GLY E  47
GLY E  51
GLY E  48
1.31A
EPE  E 202 (-3.9A)
EPE  E 202 (-4.3A)
None
EPE  E 202 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER C 128
GLY C  97
GLY C 133
GLY C 130
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  51
GLY B  47
GLY E 130
1.30A
None
None
None
EPE  E 202 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
GLY E 133
GLY B  46
GLY B  47
GLY E 130
GLY B  51
1.76A
None
None
None
EPE  E 202 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY E 133
GLY E 130
1.06A
None
None
None
EPE  E 202 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER D 128
GLY D  97
GLY D 133
GLY D 130
1.72A
None
None
None
EDO  D 205 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER E 128
GLY E  97
GLY E 133
GLY E 130
1.75A
EPE  E 202 (-4.6A)
None
None
EPE  E 202 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER A 128
GLY A  97
GLY A 133
GLY A 130
1.74A
EDO  A 202 (-4.3A)
EDO  A 202 ( 4.9A)
None
EDO  A 202 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.27A
EDO  D 209 ( 4.7A)
EDO  D 206 (-4.5A)
EDO  D 206 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR C 152
GLY C   8
PHE C   6
1.71A
EDO  C 203 (-4.8A)
EDO  C 203 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR D 152
GLY D   8
PHE D   6
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 130
GLY E 133
GLY B  46
GLY B  48
1.24A
EPE  E 202 ( 4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY E 133
GLY B  48
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY E 133
GLY E 130
GLY B  47
1.29A
None
None
EPE  E 202 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY E 133
GLY B  48
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
GLY B  51
GLY B  46
GLY E 130
GLY B  47
GLY E 133
1.64A
None
None
EPE  E 202 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER B 128
GLY B  97
GLY B 133
GLY B 130
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
GLY E 133
GLY B  47
GLY B  48
GLY B  46
GLY B  51
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 130
GLY E 133
GLY B  46
GLY B  48
1.25A
EPE  E 202 ( 4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  47
GLY B  51
GLY B  46
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY E 133
GLY E 130
GLY B  47
1.28A
None
None
EPE  E 202 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.27A
EDO  D 209 ( 4.7A)
EDO  D 206 (-4.5A)
EDO  D 206 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 130
GLY B  51
GLY E 133
GLY B  48
1.27A
EPE  E 202 ( 4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
GLY B  51
GLY B  46
GLY E 130
GLY B  47
GLY E 133
1.65A
None
None
EPE  E 202 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  48
GLY E  47
GLY E  46
GLY E  51
1.29A
EPE  E 202 ( 4.8A)
EPE  E 202 (-4.3A)
EPE  E 202 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY E 133
GLY E 130
1.12A
None
None
None
EPE  E 202 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  47
GLY B  51
GLY B  46
1.06A
None
APR  B 201 (-3.6A)
None
EDO  B 202 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  48
GLY E  47
GLY E  46
GLY E  51
1.15A
APR  E 201 (-3.4A)
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  51
GLY D  47
GLY D  48
GLY D  46
1.31A
None
APR  D 201 ( 4.3A)
EDO  D 204 ( 3.4A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  51
GLY D  47
GLY D  48
GLY D  46
1.28A
None
APR  D 201 ( 4.3A)
EDO  D 204 ( 3.4A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.17A
EDO  D 204 ( 3.4A)
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  51
GLY E  47
GLY E  48
GLY E  46
1.29A
None
APR  E 201 (-4.4A)
APR  E 201 (-3.4A)
APR  E 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.16A
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.21A
EDO  D 204 ( 3.4A)
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  47
GLY E  46
GLY E  48
GLY E  51
1.12A
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
APR  E 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  46
GLY E 133
GLY B  48
1.06A
None
EDO  B 202 (-3.9A)
None
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  47
GLY D  46
GLY D  48
GLY D  51
1.11A
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
EDO  D 204 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  47
GLY D  46
GLY D  48
GLY D  51
1.09A
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
EDO  D 204 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  51
GLY E  47
GLY E  48
GLY E  46
1.31A
None
APR  E 201 (-4.4A)
APR  E 201 (-3.4A)
APR  E 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  46
GLY E  47
GLY E  51
GLY E  48
1.07A
APR  E 201 (-3.9A)
APR  E 201 (-4.4A)
None
APR  E 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.11A
APR  A 201 (-4.2A)
APR  A 201 (-4.1A)
None
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.19A
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  46
GLY B  47
GLY E 133
1.26A
None
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.19A
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  47
GLY C  46
GLY C  48
GLY C  51
1.13A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.08A
APR  A 201 (-4.2A)
APR  A 201 (-4.1A)
None
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  47
GLY C  46
GLY C  48
GLY C  51
1.11A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  46
GLY C  47
GLY C  51
GLY C  48
1.07A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  46
GLY B  47
GLY E 133
1.26A
None
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  46
GLY B  47
GLY B  51
1.24A
None
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  46
GLY B  47
GLY B  51
1.23A
None
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY B  48
GLY B  51
1.25A
APR  B 201 (-3.6A)
EDO  B 202 (-3.9A)
APR  B 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.13A
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  46
GLY C  47
GLY C  51
GLY C  48
1.05A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
PRO E 136
GLY B  51
GLY B  46
GLY E 133
1.25A
EDO  B 202 (-4.7A)
None
EDO  B 202 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
PRO E 136
GLY B  47
GLY B  51
GLY B  46
1.20A
EDO  B 202 (-4.7A)
APR  B 201 (-3.6A)
None
EDO  B 202 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.21A
APR  C 201 (-3.5A)
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR C 152
GLY C   8
PHE C   6
1.76A
None
EDO  C 204 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  47
GLY E  46
GLY E  48
GLY E  51
1.10A
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
APR  E 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  46
GLY E  47
GLY E  51
GLY E  48
1.06A
APR  E 201 (-3.9A)
APR  E 201 (-4.4A)
None
APR  E 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
SER B 111
GLY B  79
GLY B  97
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  48
GLY E  47
GLY E  46
GLY E  51
1.19A
APR  E 201 (-3.4A)
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  46
GLY D  47
GLY D  51
GLY D  48
1.06A
APR  D 201 (-3.8A)
APR  D 201 ( 4.3A)
None
EDO  D 204 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR E 152
GLY E   8
PHE E   6
1.76A
None
EDO  E 203 (-4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.17A
APR  C 201 (-3.5A)
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.22A
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  46
GLY E 133
GLY B  48
1.06A
None
EDO  B 202 (-3.9A)
None
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.21A
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY B  48
GLY B  51
1.28A
APR  B 201 (-3.6A)
EDO  B 202 (-3.9A)
APR  B 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  46
GLY D  47
GLY D  51
GLY D  48
1.04A
APR  D 201 (-3.8A)
APR  D 201 ( 4.3A)
None
EDO  D 204 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
MES  A 201 ( 4.8A)
MES  A 201 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.26A
None
MES  C 201 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER B 128
GLY B  97
GLY B 133
GLY B 130
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR C 152
GLY C   8
PHE C   6
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.26A
None
MES  C 201 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
MES  A 201 ( 4.8A)
MES  A 201 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR A 152
GLY A   8
PHE A   6
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.79A
None
None
PJE  C   5 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
ARG A 197
GLY A 230
PRO A 227
THR A 225
1.70A3.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 596
PHE A 594
1.01A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 831
PRO A 830
LEU A 829
1.50A1.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 597
PHE A 594
0.98A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 786
TRP A 617
GLY A 616
1.75A4.05
1.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 925
GLY A 597
PHE A 594
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 925
GLY A 596
PHE A 594
0.87A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.80A
None
None
JRY  A 401 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A 143
GLY A 146
GLY A  29
1.26A
None
JRY  A 401 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 596
PHE A 594
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 597
PHE A 594
0.90A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		7bv1 NSP12
(SARS-CoV-2)		3 / 3
TYR A 831
PRO A 830
LEU A 829
1.49A1.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 597
PHE A 594
0.94A
None
None
C  T  15 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 596
PHE A 594
1.05A
None
None
C  T  15 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		7bv2 NSP12
(SARS-CoV-2)		3 / 3
TYR A 831
PRO A 830
LEU A 829
1.54A1.04
None