Ligand ID: 9F2


Drugbank ID:
DB01212
(Ceftriaxone)


Indication:
For the treatment of the infections (respiratory, skin, soft tissue, UTI, ENT) caused by S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph

Get human targets for 9F2 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '9F2' AND SARS-COV-2 / COVID-19 STRUCTURES

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5r84 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ASN A 180
ARG A 105
ARG A  40
GLY A 179
ASP A 176
1.73A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.69A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A22.89

None
ELL  D   3 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6m0j SPIKE RECEPTOR
BINDING DOMAIN
(SARS-CoV-2)		4 / 8
ASN E 422
PHE E 400
ILE E 402
GLY E 404
1.24A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m0j ACE2
SPIKE RECEPTOR
BINDING DOMAIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PRO E 499
ASN E 501
GLY E 504
GLY A 354
ASP A 355
1.38A21.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m0j ACE2
SPIKE RECEPTOR
BINDING DOMAIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PRO E 499
ASN E 501
GLY E 504
GLY A 354
ASP A 355
1.40A21.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A22.89

None
ELL  D   3 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.78A22.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PRO F 499
ASN F 501
GLY F 504
GLY F 502
ASP D 355
1.43A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PRO F 499
ASN F 501
GLY F 504
GLY F 502
ASP D 355
1.47A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		4 / 8
ASN F 422
PHE F 400
ILE F 402
GLY F 404
1.31A20.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.63A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A23.08
None
3WL  A 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER D 147
SER D 144
PRO D 122
GLY D 146
GLY D  29
1.72A23.08
None
3WL  D 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 147
SER B 144
PRO B 122
GLY B 146
GLY B  29
1.62A23.08

None
3WL  B 401 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A23.08
None
3WL  A 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER D 147
SER D 144
PRO D 122
GLY D 146
GLY D  29
1.67A23.08

None
3WL  D 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 147
SER B 144
PRO B 122
GLY B 146
GLY B  29
1.65A23.08
None
3WL  B 401 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 301
ASN B 214
THR B 304
GLY B 215
ASP B 216
1.65A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER C 147
SER C 144
PRO C 122
GLY C 146
GLY C  29
1.69A23.08
None
3WL  C 401 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER C 147
SER C 144
PRO C 122
GLY C 146
GLY C  29
1.66A23.08
None
3WL  C 401 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.68A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.62A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.60A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.60A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.56A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.59A23.08

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A23.08

None
3WL  A 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.54A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.61A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ASN B 180
ARG B 105
ARG B  40
GLY B 179
ASP B 176
1.66A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.64A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 147
SER B 144
PRO B 122
GLY B 146
GLY B  29
1.66A23.08
None
3WL  B 401 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.71A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
ASN D  65
PHE D  66
ARG D  60
ILE D  43
1.71A22.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER D 147
SER D 144
PRO D 122
GLY D 146
GLY D  29
1.70A23.08
None
3WL  D 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 301
ASN B 214
THR B 304
GLY B 215
ASP B 216
1.71A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.64A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.62A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER C 147
SER C 144
PRO C 122
GLY C 146
GLY C  29
1.64A23.08

None
3WL  C 401 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.79A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.68A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.63A23.08

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.68A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.53A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 562
ARG A 654
THR A 531
THR A 567
GLU A 658
1.76A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ILE A 562
ASN A 507
GLY A 559
GLU A 665
1.75A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
PHE A 480
THR A 591
ILE A 579
GLY A 590
1.23A16.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.51A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN A 787
THR C 723
THR C1066
GLY C1046
GLY A 889
1.25A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.46A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE C 643
THR A 866
ILE C 670
GLY C 669
1.19A13.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.52A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.50A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.46A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN B 280
GLY B 283
THR B 284
ASP B 287
GLU B 224
1.77A12.07
NAG  B1316 ( 4.8A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.49A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.46A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B 692
SER B 605
THR B 602
GLY B 601
GLY B 311
1.44A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B 692
SER B 605
THR B 602
GLY B 601
GLY B 311
1.48A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 692
SER A 605
THR A 602
GLY A 601
GLY A 311
1.43A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.54A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE C 598
THR C 602
GLY C 601
ASP C 663
GLU C 309
1.48A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN A 787
THR C 723
THR C1066
GLY C1046
GLY A 889
1.39A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.53A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.52A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.48A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
THR A 768
ILE C 312
THR C 302
THR C 299
ASP C 663
1.79A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR A 768
ILE C 312
THR C 302
THR C 299
ASP C 663
1.80A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.51A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.49A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 692
SER A 605
THR A 602
GLY A 601
GLY A 311
1.44A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 692
SER A 605
THR A 602
GLY A 601
GLY A 311
1.47A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR A 768
ILE C 312
THR C 302
THR C 299
ASP C 663
1.78A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.73A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.46A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.73A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.74A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE C 692
THR C 602
GLY C 601
THR C 599
GLY C 311
1.38A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.52A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN C 787
THR B 723
THR B1066
GLY B1046
GLY C 889
1.42A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.77A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.52A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		6 / 12
ILE C 692
SER C 605
THR C 602
GLY C 601
THR C 599
GLY C 311
1.55A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE C 326
THR C 323
GLY C 550
THR C 549
GLY C 548
1.47A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.50A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.77A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B 692
SER B 605
THR B 602
GLY B 601
GLY B 311
1.56A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		6 / 12
ILE C 692
SER C 605
THR C 602
GLY C 601
THR C 599
GLY C 311
1.57A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.48A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
ASN A 422
PHE A 400
ARG A 403
ILE A 402
GLY A 404
1.74A14.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B  94
LYS C  49
GLY C 116
THR C 115
GLY C 114
1.33A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B  94
LYS C  49
GLY C 116
THR C 115
GLY C 114
1.36A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B  94
LYS C  49
GLY C 116
THR C 115
GLY C 114
1.42A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B  94
LYS C  49
GLY C 116
THR C 115
GLY C 114
1.41A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_2
(BETA-LACTAMASE)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 4
CYH B 117
ILE A 116
PRO A 119
THR B 121
1.42A22.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 12
GLN H   1
SER H  96
SER C 383
GLY H  97
GLY H  94
1.60A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
ASN C 422
PHE C 400
ILE C 402
GLY C 404
1.24A18.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
PHE C 400
ARG C 403
ILE C 402
GLY C 404
1.41A18.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6w4h NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.78A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w4h NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.51A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w4h NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.66A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6964
ARG A7014
ARG A7053
GLY A7076
THR A6856
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6964
ARG A7014
ARG A7053
GLY A7076
THR A6856
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w61 NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.73A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.68A
None
X77  A 401 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.71A23.08
None
X77  A 401 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.69A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A
None
X77  A 401 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASN A6862
THR A6889
GLY A6890
THR A6891
ASP A6923
1.80A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.68A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.64A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.49A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.65A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.55A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.76A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER C7074
ILE C7069
SER C7071
GLY C7076
GLY C6962
1.59A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.78A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.53A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		6 / 12
ASN C6862
ARG C6864
THR C6889
GLY C6890
THR C6891
ASP C6923
1.79A19.33
None
FMT  C7106 ( 2.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.78A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.69A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ASN B4315
THR B4311
GLY B4303
THR B4304
GLY B4305
1.80A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.76A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.79A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.77A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		6 / 12
SER D4320
PRO D4353
THR D4311
GLY D4303
THR D4304
GLY D4305
1.65A19.78
None
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.78A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
SER A7071
GLY A7076
GLY A6962
1.64A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.79A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
PRO D4353
THR D4300
THR D4302
GLY D4303
GLY D4305
1.78A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
ILE A  65
PRO A  57
THR A  35
GLY A  38
ASP A  60
1.53A19.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ILE E 304
GLY F 316
GLY E 287
ASP E 288
1.78A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.45A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE F 304
SER E 312
GLY E 316
GLY F 287
ASP F 288
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.52A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN B 294
SER A 312
GLY A 316
GLY B 287
ASP B 288
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.50A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE B 337
ARG A 262
THR B 334
GLY A 284
GLY B 316
1.76A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN E 294
SER F 312
GLY F 316
GLY E 287
ASP E 288
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN F 294
SER E 312
GLY E 316
GLY F 287
ASP F 288
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ILE B 304
GLY A 316
GLY B 287
ASP B 288
1.76A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.56A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.51A
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ARG F 276
THR F 263
THR F 296
GLY F 295
1.68A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PHE E 314
ARG E 319
ILE E 320
GLY E 321
1.78A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN A 294
SER B 312
GLY B 316
GLY A 287
ASP A 288
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE D 304
SER C 312
GLY C 316
GLY D 287
ASP D 288
1.71A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ARG A 276
THR A 263
THR A 296
GLY A 295
1.68A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.51A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN C 294
SER D 312
GLY D 316
GLY C 287
ASP C 288
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE B 337
ARG A 262
THR B 334
GLY A 284
GLY B 316
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.47A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.50A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE A 304
SER B 312
GLY B 316
GLY A 287
ASP A 288
1.69A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.56A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.53A
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ILE A 304
GLY B 316
GLY A 287
ASP A 288
1.75A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE F 337
ARG E 262
THR F 334
GLY E 284
GLY F 316
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.47A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN D 294
SER C 312
GLY C 316
GLY D 287
ASP D 288
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE A 304
SER B 312
GLY B 316
GLY A 287
ASP A 288
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.52A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE C 304
SER D 312
GLY D 316
GLY C 287
ASP C 288
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ILE C 304
GLY D 316
GLY C 287
ASP C 288
1.75A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.55A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.49A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE C 304
SER D 312
GLY D 316
GLY C 287
ASP C 288
1.67A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.54A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.53A
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.49A
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE B 304
SER A 312
GLY A 316
GLY B 287
ASP B 288
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE E 337
ARG F 262
THR E 334
GLY F 284
GLY E 316
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.49A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ARG B 276
THR B 271
GLN B 283
GLY B 275
1.64A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE D 337
ARG C 262
THR D 334
GLY C 284
GLY D 316
1.71A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.52A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE E 304
SER F 312
GLY F 316
GLY E 287
ASP E 288
1.74A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.53A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE B 304
SER A 312
GLY A 316
GLY B 287
ASP B 288
1.73A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.51A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE D 304
SER C 312
GLY C 316
GLY D 287
ASP D 288
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ILE F 304
GLY E 316
GLY F 287
ASP F 288
1.75A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN E 283
PRO E 279
ASN E 285
THR F 332
GLY F 321
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.44A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ILE D 304
GLY C 316
GLY D 287
ASP D 288
1.79A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ARG C 276
THR C 263
THR C 296
GLY C 295
1.66A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE F 337
ARG E 262
THR F 334
GLY E 284
GLY F 316
1.73A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.56A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE D 337
ARG C 262
THR D 334
GLY C 284
GLY D 316
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.50A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE E 337
ARG F 262
THR E 334
GLY F 284
GLY E 316
1.80A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.50A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ASN B 345
GLN E 289
ILE E 292
GLY E 287
1.52A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE E 304
SER F 312
GLY F 316
GLY E 287
ASP E 288
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.56A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.56A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE F 304
SER E 312
GLY E 316
GLY F 287
ASP F 288
1.69A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE C 337
ARG D 262
THR C 334
GLY D 284
GLY C 316
1.79A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
SER A7071
GLY A7076
GLY A6962
1.62A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.61A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.78A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.79A19.78
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.67A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
ASN D4315
THR D4311
GLY D4303
THR D4304
GLY D4305
1.80A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.76A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.68A
None
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.58A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER C7074
ILE C7069
SER C7071
GLY C7076
GLY C6962
1.61A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.79A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
PRO D4353
THR D4300
THR D4302
GLY D4303
GLY D4305
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ASN A6862
THR A6889
GLY A6890
THR A6891
ASP A6923
1.76A20.97
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		6 / 12
SER D4320
PRO D4353
THR D4311
GLY D4303
THR D4304
GLY D4305
1.65A
None
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.71A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B  78
ILE B 157
PRO B  73
ARG A 107
THR A  57
1.66A
None
None
None
MES  B 201 (-4.8A)
MES  B 201 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.68A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.72A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.72A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ASN B  77
PHE A 171
ARG A 107
GLN A  58
1.46A17.30
None
None
MES  B 201 (-4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.67A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.74A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.68A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.66A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		6 / 12
SER D4320
PRO D4353
THR D4311
GLY D4303
THR D4304
GLY D4305
1.64A
None
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		6 / 12
ASN C6862
ARG C6864
THR C6889
GLY C6890
THR C6891
ASP C6923
1.79A20.97
None
FMT  C7106 ( 2.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.66A
None
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.79A19.78
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.61A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.80A19.78
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER C7074
ILE C7069
SER C7071
GLY C7076
GLY C6962
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.77A
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.77A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
PRO D4353
THR D4300
THR D4302
GLY D4303
GLY D4305
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.77A19.78
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.78A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.57A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.77A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.75A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ASN A6862
THR A6889
GLY A6890
THR A6891
ASP A6923
1.77A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER C7074
ILE C7069
SER C7071
GLY C7076
GLY C6962
1.60A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
SER A7071
GLY A7076
GLY A6962
1.63A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
PRO B4353
ASN B4315
GLY B4303
THR B4304
GLY B4305
1.78A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
SER A 274
PRO A 271
THR A 196
THR A 275
ASP A  88
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
SER B 274
PRO B 271
THR B 196
THR B 275
ASP B  88
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.70A23.08
None
U5G  A 401 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.65A
None
U5G  A 401 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ASN A  65
PHE A  66
ARG A  60
ILE A  43
1.72A22.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.68A
None
U5G  A 401 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASN C 101
PHE C 132
ILE C 131
GLY C  48
1.77A19.76
None
APR  C 201 (-3.5A)
APR  C 201 (-3.9A)
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wq3 NSP10
(SARS-CoV-2)		5 / 12
PRO B4353
ASN B4315
GLY B4303
THR B4304
GLY B4305
1.76A19.78
None
None
SO4  B4403 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASN A6827
THR A6993
ILE A7035
GLY A6806
1.71A19.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6wq3 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.79A19.78
None
None
SO4  B4403 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6964
ARG A7014
ARG A7053
GLY A7076
THR A6856
1.72A
None
None
None
None
8NK  A7103 (-2.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.51A
None
None
None
None
8NK  A7103 (-2.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wq3 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.77A19.78
None
None
SO4  B4403 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wq3 NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.67A
None
None
None
SO4  B4403 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7088
SER A7090
THR A6915
GLY A6911
ASP A6895
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6964
ARG A7014
ARG A7053
GLY A7076
THR A6856
1.74A
None
None
None
None
8NK  A7103 (-2.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.63A19.17
None
DMS  A 405 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A19.17
None
DMS  A 405 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.68A19.17
None
DMS  A 405 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
PRO A 111
ARG A 109
GLY A  76
THR A  75
GLY A 107
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
ASN A  35
THR A 125
GLN A 120
ILE A  34
1.71A17.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 106
THR A   9
GLY A  76
THR A  75
GLY A  74
1.55A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 106
THR A   9
GLY A  76
THR A  75
GLY A  74
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 106
THR A   9
GLY A  76
THR A  75
GLY A  74
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ILE H  50
PRO L 101
GLY E 381
THR H 104
1.78A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN A 422
PHE A 400
ILE A 402
GLY A 404
1.17A20.87
None
None
None
DMS  A 903 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ARG H  59
THR L 100
GLY E 413
GLU H  57
1.67A
None
None
None
None
MLI  E 908 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE E 400
ARG E 403
ILE E 402
GLY E 404
1.51A20.87
None
None
None
DMS  E 902 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.60A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN E 422
PHE E 400
ILE E 402
GLY E 404
1.18A20.87
None
None
None
DMS  E 902 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PHE A 392
THR B 104
ILE C  34
GLY A 381
1.79A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PHE E 392
THR H 104
ILE L  34
GLY E 381
1.78A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE A 400
ARG A 403
ILE A 402
GLY A 404
1.45A20.87
None
None
None
DMS  A 903 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ARG H  59
THR L 100
GLY E 413
GLU H  57
1.69A20.94
None
None
None
None
MLI  E 908 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 472
PRO A 491
ARG A 454
THR A 478
GLY A 476
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
GLN B   1
SER C  62
THR E 385
GLY C  63
THR H   0
1.77A
None
MLI  B 303 ( 3.9A)
None
None
MLI  B 303 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.50A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.52A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.53A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.50A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
ASN E 422
PHE E 400
ARG E 403
ILE E 402
GLY E 404
1.57A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.52A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.53A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A
None
P6N  A 502 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.61A
None
P6N  A 502 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A23.08
None
P6N  A 502 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PHE E 392
THR H 104
ILE L  34
GLY E 381
1.78A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN A 422
PHE A 400
ILE A 402
GLY A 404
1.19A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR C 102
ILE B 102
TYR B  32
THR A 385
ASP A 428
1.59A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ARG H  59
THR L 100
GLY E 413
GLU H  57
1.69A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE E 400
ARG E 403
ILE E 402
GLY E 404
1.51A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR C 102
ILE B 102
TYR B  32
THR A 385
ASP A 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.60A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR C 102
ILE B 102
TYR B  32
THR A 385
ASP A 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER B 103
ILE B  50
PRO C 101
GLY A 381
THR B 104
1.78A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER B 103
ARG B  59
THR C 100
GLY A 413
GLU B  57
1.69A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ILE H  50
PRO L 101
GLY E 381
THR H 104
1.78A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE A 400
ARG A 403
ILE A 402
GLY A 404
1.51A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN E 422
PHE E 400
ILE E 402
GLY E 404
1.18A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER B 103
ARG B  59
THR C 100
GLY A 413
GLU B  57
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR C 102
ILE B 102
TYR B  32
THR A 385
ASP A 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PHE A 392
THR B 104
ILE C  34
GLY A 381
1.78A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ARG H  59
THR L 100
GLY E 413
GLU H  57
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A23.08
None
DMS  A 403 ( 2.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A
None
DMS  A 403 ( 2.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.62A
None
DMS  A 403 ( 2.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN A 101
PHE A 132
ILE A 131
GLY A  48
1.77A20.60
None
EDO  A 202 (-3.9A)
EDO  A 202 (-4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN A 101
PHE A 132
ILE A 131
GLY A  48
1.74A20.60
None
APR  A 201 (-3.7A)
APR  A 201 (-3.1A)
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN B 101
PHE B 132
ILE B 131
GLY B  48
1.75A20.60
None
APR  B 201 (-3.5A)
APR  B 201 (-3.2A)
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A
None
PJE  C   5 ( 4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.74A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
ASN A  65
PHE A  66
ARG A  60
ILE A  43
1.78A22.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A  27
PRO A  21
ARG A  74
THR A  26
GLY A  25
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.78A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.76A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ILE A 562
ASN A 507
GLY A 559
GLU A 665
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.78A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.75A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.74A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.77A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
PHE A 480
THR A 591
ILE A 579
GLY A 590
1.21A16.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.58A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A
None
DMS  A 402 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
ASN A  65
PHE A  66
ARG A  60
ILE A  43
1.78A22.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.58A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 562
ARG A 654
THR A 531
THR A 567
GLU A 658
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
PHE A 480
THR A 591
ILE A 579
GLY A 590
1.17A16.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ILE A 562
ASN A 507
GLY A 559
GLU A 665
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 562
ARG A 654
THR A 531
THR A 567
GLU A 658
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
PHE A 480
THR A 591
ILE A 579
GLY A 590
1.30A16.22
None
None
None
A  T  13 ( 3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ASN A 414
PHE A 415
ARG A 858
GLY A 841
1.79A16.22
None
None
U  P  17 ( 3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
PHE A 812
ARG A 583
THR A 582
GLY A 584
1.64A16.22
None