Results

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	RMSD	Seq. Identity (%)	HETATM
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	1ssk	NUCLEOCAPSID PROTEIN (SARSr-CoV)	3 / 3	THR A 143 THR A 144 PHE A 149	1.22A	13.64	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1uk3	3C-LIKE PROTEINASE (SARSr-CoV)	5 / 12	LEU A 262 THR A 225 THR A 224 ASN A 221 TYR A 209	1.77A	20.51	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	1wnc	E2 GLYCOPROTEIN (SARSr-CoV)	5 / 12	ILE F1164 ASP F1165 ALA A 938 ALA A 940 ASN A 937	1.69A	15.61	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	1wnc	E2 GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 932 GLN F 939 ALA D1155 ALA F 940 ASN D1154	1.59A	13.85	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1x7q	HLA, A-11 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.79A	17.81	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	1z1j	3C-LIKE PROTEINASE (SARSr-CoV)	4 / 4	ASN B1221 LEU B1262 PHE B1219 TYR B1209	1.77A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1zva	E2 GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASP A 60 ASN A 54 PHE A 27	0.85A	13.87	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2ajf	ACE2 SPIKE PROTEIN (Homo sapiens; SARSr-CoV)	3 / 3	ASN B 33 LEU F 443 PHE B 28	1.07A	21.02	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ajf	SPIKE PROTEIN (SARSr-CoV)	5 / 12	ASP E 385 SER E 386 THR E 363 ALA E 422 TYR E 410	1.70A	19.70	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	2cjr	NUCLEOCAPSID PROTEIN (SARS-COV TW1)	5 / 12	ILE A 321 TYR A 334 SER A 319 ALA B 312 ALA A 309	1.71A	12.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2dd8	IGG HEAVY CHAIN SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP S 392 THR H 70 THR H 68 TRP H 47 TYR S 491	1.62A	18.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2dd8	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN S 427 PHE S 483 TYR S 494	1.31A	19.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2dd8	IGG HEAVY CHAIN SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP S 392 THR H 70 THR H 68 TRP H 47 TYR S 491	1.67A	19.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2dd8	IGG HEAVY CHAIN SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP S 392 THR H 70 THR H 68 TRP H 47 TYR S 491	1.67A	18.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2dd8	IGG HEAVY CHAIN SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP S 392 THR H 70 THR H 68 TRP H 47 TYR S 491	1.65A	19.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2fav	REPLICASE POLYPROTEIN 1AB (PP1AB) (ORF1AB) (SARSr-CoV)	5 / 12	SER C 30 ALA C 90 TYR C 153 ASN C 5 TYR C 10	1.78A	16.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2fe8	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN B 14 LEU B 65 PHE B 9	0.82A	19.88	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2fe8	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.80A	23.63	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2fyg	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	5 / 12	ASP A 64 ALA A 54 TYR A 126 ASN A 114 CYH A 103	1.76A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ga6	ORF1A POLYPROTEIN (SARSr-CoV)	3 / 3	ASP I 91 ASN G 85 PHE G 89	1.33A	17.15	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ga6	ORF1A POLYPROTEIN (SARSr-CoV)	5 / 12	ASP D 64 ALA D 54 TYR D 126 ASN D 114 CYH D 103	1.74A	17.15	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2ghw	ANTI-SCFV ANTIBODY, 80R SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP D 54 TYR D 53 SER D 52 ALA C 430 ASN C 427	1.71A	21.34	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2ghw	ANTI-SCFV ANTIBODY, 80R (Homo sapiens)	3 / 3	THR D 134 THR D 135 PHE D 230	1.20A	19.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2ghw	ANTI-SCFV ANTIBODY, 80R SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP D 54 TYR D 53 SER D 56 ALA C 430 ASN C 427	1.71A	21.34	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ghw	ANTI-SCFV ANTIBODY, 80R (Homo sapiens)	5 / 12	SER D 163 THR D 229 THR D 134 ALA D 157 TYR D 103	1.62A	23.62	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ghw	ANTI-SCFV ANTIBODY, 80R (Homo sapiens)	5 / 12	ASP B 202 SER B 154 THR B 134 THR B 135 TRP B 167	1.56A	23.62	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2ghw	ANTI-SCFV ANTIBODY, 80R SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP B 182 TYR A 442 SER B 163 ASN A 457 TYR A 440	1.70A	19.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2h85	PUTATIVE ORF1AB POLYPROTEIN (SARSr-CoV)	3 / 3	ASN A 277 LEU A 254 PHE A 279	0.95A	21.05	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2k87	NSP3 OF REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASP A 61 ASN A 59 PHE A 54	1.46A	12.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2ofz	NUCLEOCAPSID PROTEIN (SARS-COV Tor2)	3 / 3	ASN A 155 PHE A 54 TYR A 112	1.32A	16.88	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2og3	NUCLEOCAPSID PROTEIN (SARS-COV Tor2)	3 / 3	THR A 158 THR A 55 PHE A 111	0.91A	14.96	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2ozk	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARSr-CoV)	3 / 3	ASN C 277 LEU C 254 PHE C 279	1.18A	21.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2pwx	3C-LIKE PROTEINASE (SARS-COV BJ01)	3 / 3	ASN A 221 PHE A 219 TYR A 209	1.24A	22.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	2pwx	3C-LIKE PROTEINASE (SARS-COV BJ01)	4 / 4	ASN A 221 LEU A 262 PHE A 219 TYR A 209	1.61A	20.26	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2q6g	POLYPEPTIDE CHAIN REPLICASE POLYPROTEIN 1AB (SARS-COV BJ01)	5 / 12	SER C 7 LEU A 86 THR A 175 TYR A 54 CYH A 44	1.80A	3.10	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2rhb	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARSr-CoV)	3 / 3	ASN F 277 LEU F 254 PHE F 279	0.99A	21.51	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2rhb	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARSr-CoV)	3 / 3	ASP A 282 ASN B 163 PHE A 268	1.40A	21.97	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2rhb	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARSr-CoV)	3 / 3	ASN F 277 LEU F 254 PHE F 279	0.90A	21.97	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2w2g	NSP3 (SARSr)	3 / 3	ASN B 427 PHE B 414 TYR B 487	1.43A	20.47	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2xyq	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.70A	19.46	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyq	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.71A	20.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2xyq	NSP10 PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.66A	20.71	None None None None ZN B1132 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2xyq	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.68A	19.46	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2xyq	NSP10 PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.59A	20.71	None None None None ZN B1132 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyq	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.70A	20.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.66A	19.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2xyr	NSP10 PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.66A	20.28	None None None None ZN B1132 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.64A	19.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.66A	20.09	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2xyr	NSP10 PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.59A	20.28	None None None None ZN B1132 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyr	NSP10 (SARSr-CoV)	5 / 12	ASP B 64 ALA B 54 TYR B 126 ASN B 114 CYH B 103	1.76A	16.45	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.67A	20.09	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.70A	19.87	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3bgf	F26G19 FAB SPIKE PROTEIN S1 (Mus musculus; SARSr-CoV)	5 / 12	ILE H 97 ASP S 392 ALA L 51 ALA L 50 TYR S 491	1.70A	16.99	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3bgf	SPIKE PROTEIN S1 (SARSr-CoV)	5 / 12	TYR A 436 ASN A 437 THR A 433 THR A 431 TYR S 338	1.78A	16.94	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3bgf	F26G19 FAB SPIKE PROTEIN S1 (Mus musculus; SARSr-CoV)	3 / 3	THR B 31 THR B 30 PHE A 360	1.10A	18.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3d0g	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.07A	21.11	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3d0g	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 385 SER F 386 THR F 363 ALA F 422 TYR F 410	1.75A	19.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3d0h	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 385 SER F 386 THR F 363 ALA F 422 TYR F 410	1.77A	19.49	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3d0h	ACE2 SPIKE GLYCOPROTEIN (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASN B 33 LEU F 443 PHE B 28	0.96A	21.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3d0i	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 385 SER F 386 THR F 363 ALA F 422 TYR F 410	1.74A	19.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3e91	3C-LIKE PROTEINASE (SARSr-CoV)	3 / 3	THR A 226 THR A 225 PHE A 223	1.29A	20.78	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3e91	3C-LIKE PROTEINASE (SARSr-CoV)	5 / 12	ILE B 200 TRP B 207 ALA B 285 ALA B 284 TYR B 239	1.64A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3e9s	NSP3 (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.95A	22.65	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3f9g	3C-LIKE PROTEINASE (SARSr-CoV)	3 / 3	THR A 226 THR A 225 PHE A 223	1.24A	22.03	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3i6k	HLA, A-2 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.73A	18.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3i6k	HLA, A-2 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.70A	17.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3i6k	HLA, A-2 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.67A	17.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3i6k	HLA, A-2 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.71A	19.81	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3mj5	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.89A	22.65	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3mj5	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.86A	23.13	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.68A	20.63	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3r24	2'-O-METHYL TRANSFERASE NSP10 AND NSP11 (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.61A	20.91	None None None None ZN B 998 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.68A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.69A	20.63	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.66A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.73A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3sck	ACE2 SPIKE GLYCOPROTEIN (Paguma larvata; Homo sapiens; SARSr-CoV)	5 / 12	ASP A 355 TYR A 41 THR E 433 ALA A 65 ASN A 49	1.70A	22.48	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3sck	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 385 SER F 386 THR F 363 ALA F 422 TYR F 410	1.73A	20.19	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3sck	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	5 / 12	ASP A 225 THR A 519 TRP A 566 TYR A 207 ASN A 397	1.64A	22.48	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3scl	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASP B 216 ASN B 578 PHE B 400	1.29A	22.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3scl	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.15A	22.85	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3scl	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.10A	22.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3sna	3C-LIKE PROTEINASE (SARSr-CoV)	3 / 3	ASN A 221 PHE A 219 TYR A 209	1.37A	22.57	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3snc	3C-LIKE PROTEINASE PEPTIDE ALDEHYDE INHIBITOR AC-NSTSQ-H (SARSr-CoV)	5 / 12	ASP A 187 SER H 4 GLN A 189 ALA A 46 TYR A 54	1.73A	21.47	None ECC H 5 ( 4.9A) None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4m0w	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.92A	22.43	None GOL A 405 (-4.2A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4m0w	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.91A	23.36	None GOL A 405 (-4.2A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4ow0	PAPAIN-LIKE PROTEASE (SARS-COV Urbani)	4 / 4	ASN A 14 LEU A 88 PHE A 56 TYR A 36	1.78A	22.65	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4rna	PAPAIN-LIKE PROTEASE (Human betacoronavirus 2c EMC/2012)	3 / 3	ASN A 114 LEU A 170 PHE A 269	1.16A	24.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4wme	MERS-COV 3CL PROTEASE (MERS-CoV)	3 / 3	ASN B 226 LEU B 272 PHE D 106	1.45A	24.24	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR D 368 ALA D 394 ALA D 396 TYR D 370 ASN D 438	1.42A	20.78	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR D 368 ALA D 394 ALA D 396 TYR D 370 ASN D 438	1.45A	21.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	4 / 4	ASN D 499 LEU D 468 PHE D 445 TYR D 446	1.45A	21.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	5 / 12	ASP C 29 SER C 33 THR C 12 ASN D 71 TYR D 69	1.80A	16.54	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	ILE B 510 TYR B 498 ALA B 308 TRP B 385 CYH B 399	1.60A	21.93	None None None G3A B 606 ( 4.1A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8s	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	3 / 3	ASN C 40 LEU D 18 PHE D 8	0.97A	17.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	ASP B 449 TYR B 447 THR B 516 ALA B 323 ASN B 521	1.74A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	4 / 4	ASN B 334 TRP B 348 LEU B 321 PHE B 384	1.77A	21.12	SAH B 605 (-4.1A) None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	3 / 3	ASP B 390 ASN B 388 PHE B 431	1.32A	22.59	None G3A B 606 (-3.8A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr)	3 / 3	ASN A 40 LEU B 18 PHE B 8	1.23A	17.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr)	3 / 3	ASN B 63 LEU B 7 PHE A 16	1.48A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr)	3 / 3	ASN C 40 LEU D 18 PHE D 8	0.99A	17.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	3 / 3	ASN C 40 LEU D 18 PHE D 8	0.87A	14.53	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr)	3 / 3	ASN D 63 LEU D 7 PHE C 16	1.35A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR B 368 THR B 378 ALA B 394 ALA B 396 ASN B 438	1.55A	21.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR D 368 ALA D 394 ALA D 396 TYR D 370 ASN D 438	1.39A	21.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	ASP B 449 TYR B 447 THR B 516 ALA B 323 ASN B 521	1.70A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	4 / 4	ASN D 499 LEU D 468 PHE D 445 TYR D 446	1.59A	21.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8u	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	3 / 3	ASN D 63 LEU D 7 PHE C 16	1.15A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5c8u	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	3 / 3	ASN D 63 LEU D 7 PHE C 16	1.15A	23.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	3 / 3	ASP D 432 ASN D 388 PHE D 401	0.98A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	4 / 4	ASN D 334 TRP D 348 LEU D 321 PHE D 384	1.64A	21.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR D 368 ALA D 394 ALA D 396 TYR D 370 ASN D 438	1.36A	20.94	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5e6j	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 4	ASN A 14 LEU A 88 PHE A 56 TYR A 36	1.55A	23.13	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5e6j	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN D 14 LEU D 65 PHE D 9	1.02A	22.43	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	5 / 12	TYR C 368 ALA C 394 ALA C 396 TYR C 370 ASN C 438	1.62A	20.61	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	4 / 4	ASN A 334 TRP A 348 LEU A 321 PHE A 384	1.77A	20.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	3 / 3	ASP C 211 ASN C 228 PHE C 233	1.22A	22.50	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	5 / 12	ASP O 64 ALA O 54 TYR O 126 ASN O 114 CYH O 103	1.74A	16.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	5 / 12	TYR A 368 ALA A 394 ALA A 396 TYR A 370 ASN A 438	1.61A	20.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	5 / 12	ILE A 510 TYR A 498 ALA A 308 TRP A 385 CYH A 399	1.49A	21.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	3 / 3	ASN M 40 LEU A 18 PHE A 8	1.16A	16.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5tl6	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 4	ASN B 14 LEU B 88 PHE B 56 TYR B 36	1.75A	22.65	SO4 B 402 (-4.2A) None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5tl6	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN D 14 LEU D 65 PHE D 9	0.82A	22.65	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5tl6	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN B 14 LEU B 65 PHE B 9	0.81A	23.37	SO4 B 402 (-4.2A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5wrg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER A1012 THR A 760 ALA A1004 ALA A1007 ASN A1005	1.65A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5wrg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP A 757 SER A 712 THR A 856 ALA A1037 ALA A1038	1.80A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5wrg	SPIKE GLYCOPROTEIN (SARSr-CoV)	4 / 4	ASN C 960 LEU C 978 PHE B 558 TYR C 723	1.71A	17.82	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5wrg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP C 385 SER C 386 THR C 363 ALA C 422 TYR C 410	1.71A	15.92	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x29	ENVELOPE SMALL MEMBRANE PROTEIN (SARSr-CoV)	5 / 12	TYR D 57 SER D 60 THR E 35 ALA E 40 ALA E 43	1.67A	11.34	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x4r	S PROTEIN (MERS-CoV)	3 / 3	ASN A 226 LEU A 179 PHE A 228	1.00A	21.38	NAG A 503 ( 4.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5x4r	S PROTEIN (MERS-CoV)	3 / 3	ASN A 226 LEU A 179 PHE A 228	1.03A	21.64	NAG A 503 ( 4.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x4r	S PROTEIN (MERS-CoV)	5 / 12	ILE A 245 ASP A 248 THR A 139 ALA A 309 ALA A 311	1.66A	21.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5x4r	S PROTEIN (MERS-CoV)	5 / 12	ASP A 83 TYR A 85 GLN A 37 ALA A 103 TYR A 293	1.64A	20.08	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.51A	23.08	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.49A	23.08	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.49A	20.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.63A	18.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN A 189 PHE A 187 TYR A 197	1.29A	20.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x58	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	ASP A 727 ASN A 721 PHE C 305	1.21A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x58	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	SER B1012 THR B 760 ALA B1004 ALA B1007 ASN B1005	1.59A	17.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x58	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	ASN C 505 PHE C 501 TYR C 383	0.90A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x59	S PROTEIN (MERS-CoV)	5 / 12	THR B 798 THR B 797 ALA B1096 ALA B1099 TYR B 947	1.77A	15.03	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	THR B 71 THR B 75 PHE B 22	0.80A	18.66	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	ASN A 960 LEU C 503 PHE C 529	1.16A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	TRP C 245 THR C 71 THR C 247 ALA C 237 ASN C 78	1.47A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	ASN A 910 LEU A 898 PHE A 779	1.15A	17.83	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	ASP B1023 SER C1012 ALA C1004 ALA C1007 ASN C1005	1.74A	18.66	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	TRP C 245 THR C 71 THR C 247 ALA C 237 ASN C 78	1.47A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	TRP C 245 THR C 71 THR C 247 ALA C 237 ASN C 78	1.47A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	SER B1012 THR B 760 ALA B1004 ALA B1007 ASN B1005	1.64A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5x5c	S PROTEIN (MERS-CoV)	3 / 3	ASN A 226 LEU A 179 PHE A 228	1.02A	16.88	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5x5c	S PROTEIN (MERS-CoV)	5 / 12	ASP C 83 TYR C 85 GLN C 37 ALA C 103 TYR C 293	1.64A	17.41	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x5c	S PROTEIN (MERS-CoV)	3 / 3	ASN B 226 LEU B 179 PHE B 228	1.00A	15.27	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x5c	S PROTEIN (MERS-CoV)	4 / 4	ASN C1169 LEU C1155 PHE C 778 TYR C 777	1.53A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x5f	S PROTEIN (MERS-CoV)	3 / 3	ASN C 619 PHE C 617 TYR C 642	1.34A	15.03	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x5f	S PROTEIN (MERS-CoV)	5 / 12	ILE C 245 ASP C 248 THR C 139 ALA C 309 ALA C 311	1.67A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5xlr	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN C 189 PHE C 187 TYR C 197	1.10A	15.90	ASN C 189 ( 0.6A) PHE C 187 ( 1.3A) TYR C 197 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5xlr	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASP C 376 ASN C 530 PHE C 527	1.23A	15.92	ASP C 376 ( 0.6A) ASN C 530 ( 0.6A) PHE C 527 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5y3e	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 81 PHE A 56	1.10A	23.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5y3q	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.90A	22.43	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5zvm	PAN-COV INHIBITORY PEPTIDE EK1 SPIKE GLYCOPROTEIN (SARSr-CoV; synthetic construct)	3 / 3	ASN B 907 LEU a 39 PHE B 909	0.91A	11.92	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6acd	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN C 960 LEU A 504 PHE A 527	0.94A	18.39	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6acd	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP C 23 TRP C 245 THR C 71 THR C 247 ALA C 237	1.74A	18.39	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6acd	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP C 23 TRP C 245 THR C 71 THR C 247 ALA C 237	1.65A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6acd	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER C1012 THR C 760 ALA C1004 ALA C1007 ASN C1005	1.63A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6acg	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN B 721 LEU B 749 PHE B 741	0.99A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6acg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ILE B1000 THR A1009 ALA A1004 ALA A1002 ASN A 759	1.63A	17.43	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6acg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	THR C 487 THR C 485 ALA C 430 TRP C 423 TYR C 494	1.73A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6acj	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP A1023 SER C1012 ALA C1004 ALA C1007 ASN C1005	1.67A	19.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6ack	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN A 427 PHE A 483 TYR A 494	0.97A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6ack	ACE2 SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	TYR D 41 THR C 431 THR C 485 ALA C 430 TYR C 436	1.79A	21.57	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6ack	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASP B 454 ASN A 158 PHE A 130	1.04A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6ack	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	THR B 71 THR B 75 PHE B 22	0.93A	19.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	THR C1058 THR C1059 PHE C1085	1.30A	19.04	None None NAG C1308 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP B 245 THR B 75 THR B 247 ALA B 237 ASN B 78	1.53A	17.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP C 245 THR C 75 THR C 247 ALA C 237 ASN C 78	1.44A	16.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP C 245 THR C 75 THR C 247 ALA C 237 ASN C 78	1.42A	16.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	ASP B1023 SER C1012 ALA C1004 ALA C1007 ASN C1005	1.70A	19.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	SER B1012 THR B 760 ALA B1004 ALA B1007 ASN B1005	1.70A	17.60	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP C 245 THR C 75 THR C 247 ALA C 237 ASN C 78	1.43A	16.37	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	SER B1012 THR B 760 ALA B1004 ALA B1007 ASN B1005	1.75A	16.37	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crw	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	SER C1012 THR C 760 ALA C1004 ALA C1007 ASN C1005	1.62A	15.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crw	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	ASN A 189 PHE A 187 TYR A 197	1.05A	15.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	ASP C1023 SER A1012 ALA A1004 ALA A1007 ASN A1005	1.68A	18.61	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.48A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.58A	17.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.47A	15.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.50A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6crz	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	ASN A 901 LEU A1031 PHE A1091	0.82A	17.40	NAG A1311 (-3.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6cs0	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	ILE C 674 THR A 848 ALA C 654 ALA C 633 TYR C 677	1.55A	17.17	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6cs0	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	ASN A 901 LEU A1031 PHE A1091	0.98A	16.01	NAG A1311 (-3.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6cs1	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	THR A 693 THR A1059 PHE A1079	0.82A	18.61	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6cs2	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	ASP B 727 ASN B 721 PHE A 305	1.04A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6cs2	ACE2 SPIKE GLYCOPROTEIN,FIBRITI N (Homo sapiens; SARSr-CoV)	5 / 12	ASP D 355 THR B 433 THR B 431 ALA B 430 TYR D 41	1.71A	21.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6iex	BETA-2-MICROGLOBULIN MHC CLASS I ANTIGEN (Homo sapiens)	5 / 12	SER B 52 THR A 240 ALA A 236 TYR B 26 TYR B 63	1.77A	12.10	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6jyt	HELICASE (SARSr-CoV)	3 / 3	ASN B 381 PHE B 422 TYR B 421	1.40A	20.97	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6jyt	HELICASE (SARSr-CoV)	3 / 3	THR B 550 THR B 549 PHE B 475	1.30A	21.81	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6jyt	HELICASE (SARSr-CoV)	3 / 3	ASP A 32 ASN A 102 PHE A 133	1.32A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6jyt	HELICASE (SARSr)	3 / 3	ASN B 9 LEU B 132 PHE B 24	1.33A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6jyt	HELICASE (SARSr-CoV)	5 / 12	ILE A 20 SER B 38 THR B 104 ALA B 108 ALA B 110	1.23A	21.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6jyt	HELICASE (SARSr)	3 / 3	ASN A 9 LEU A 132 PHE A 24	1.30A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6lzg	ACE2 (Homo sapiens)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.12A	21.11	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m0j	ACE2 (Homo sapiens)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.12A	22.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6m17	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	4 / 4	ASN C 310 LEU C 427 PHE C 48 TYR C 129	1.39A	20.40	None None LEU C 707 (-4.7A) LEU C 707 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m17	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	3 / 3	ASN C 54 LEU C 254 PHE C 312	0.82A	21.11	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m17	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	3 / 3	ASN C 54 LEU C 254 PHE C 312	0.84A	21.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m18	ACE2 (Homo sapiens)	5 / 12	TYR D 649 SER D 707 ALA B 714 ALA D 714 TYR B 633	1.44A	18.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6m18	ACE2 (Homo sapiens)	5 / 12	TYR D 649 SER D 707 ALA B 714 ALA D 714 TYR B 633	1.49A	20.10	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	ACE2 (Homo sapiens)	3 / 3	ASN B 572 LEU B 529 PHE B 555	0.96A	18.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m1d	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	3 / 3	ASN A 258 PHE A 255 TYR A 322	1.29A	20.52	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	ACE2 (Homo sapiens)	5 / 12	SER D 502 THR D 125 THR D 129 ASN D 508 TYR D 180	1.76A	18.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m1d	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	5 / 12	ASP A 486 SER A 487 THR A 121 ALA A 590 TYR A 128	1.72A	20.52	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	5 / 12	ASP A 486 SER A 487 THR A 121 ALA A 590 TYR A 128	1.79A	21.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	ACE2 (Homo sapiens)	5 / 12	SER D 502 THR D 125 THR D 129 ASN D 508 TYR D 180	1.77A	18.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m1d	ACE2 (Homo sapiens)	3 / 3	ASN B 572 LEU B 529 PHE B 555	1.05A	19.30	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	ACE2 (Homo sapiens)	3 / 3	ASP B 67 ASN B 61 PHE B 40	1.28A	18.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6nb6	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP C1023 SER B1012 ALA B1004 ALA B1007 ASN B1005	1.79A	18.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6nb7	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	THR A1098 THR A1099 PHE A1103	1.16A	18.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nb7	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER A1012 THR A 760 ALA A1004 ALA A1007 ASN A1005	1.56A	16.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nb7	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER A1012 THR A 760 ALA A1004 ALA A1007 ASN A1005	1.62A	16.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6nb7	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER A1012 THR A 760 ALA A1004 ALA A1007 ASN A1005	1.54A	17.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6nur	NSP12 (SARSr-CoV)	3 / 3	THR A 393 THR A 394 PHE A 396	1.12A	19.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nur	NSP12 (SARSr)	3 / 3	ASN A 215 PHE A 192 TYR A 237	1.03A	18.50	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6nur	NSP12 (SARSr-CoV)	3 / 3	ASN A 705 LEU A 630 PHE A 471	0.90A	19.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6nur	NSP12 (SARSr-CoV)	5 / 12	ASP A 390 ASN A 447 TYR A 453 TYR A 674 CYH A 669	1.64A	19.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6nur	NSP12 (SARSr-CoV)	4 / 4	ASN A 168 LEU A 146 PHE A 793 TYR A 787	1.73A	20.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nur	NSP12 (SARSr-CoV)	5 / 12	ASP A 465 THR A 206 ALA A 125 TYR A 728 TYR A 732	1.76A	18.50	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nur	NSP12 (SARSr-CoV)	5 / 12	SER A 759 ALA A 634 ALA A 690 TYR A 619 CYH A 622	1.72A	18.50	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6nur	NSP12 (SARSr)	3 / 3	ASN A 314 LEU A 251 PHE A 275	0.91A	18.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w41	CR3022 FAB HEAVY CHAIN CR3022 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	SER H 99 THR L 53 ALA L 51 ALA L 34 ASN L 31	1.53A	14.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6w41	CR3022 FAB HEAVY CHAIN CR3022 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	SER H 99 THR L 53 ALA L 51 ALA L 34 ASN L 31	1.58A	14.35	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w41	CR3022 FAB LIGHT CHAIN (Homo sapiens)	3 / 3	THR L 72 THR L 20 PHE L 62	1.58A	16.24	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w41	CR3022 FAB HEAVY CHAIN CR3022 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	SER H 99 THR L 53 ALA L 51 ALA L 34 ASN L 31	1.31A	14.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yla	LIGHT CHAIN (Homo sapiens)	3 / 3	THR C 78 THR C 20 PHE C 68	1.71A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yla	LIGHT CHAIN (Homo sapiens)	3 / 3	THR L 78 THR L 20 PHE L 68	1.72A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6ym0	LIGHT CHAIN (Homo sapiens)	3 / 3	THR L 78 THR L 20 PHE L 68	1.71A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yor	IGG L CHAIN (Homo sapiens)	3 / 3	THR L 78 THR L 20 PHE L 68	1.72A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yor	IGG L CHAIN (Homo sapiens)	3 / 3	THR C 78 THR C 20 PHE C 68	1.72A	15.73	None