
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
5cxv | 0HK | Tiotropium (DB01409) | Tiotropium is a long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). | MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M1 (Homo sapiens;enterobacteria phage t4;synthetic construct) | 7tm_1Phage_lysozyme | ||
5dsg | 0HK | Tiotropium (DB01409) | Tiotropium is a long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). | MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Homo sapiens;enterobacteria phage t4) | 7tm_1 | ||
5xpr | K86 | Bosentan (DB00559) | Bosentan is a dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. | ENDOTHELIN B RECEPTOR,ENDOLYSIN,ENDOTHELIN B RECEPTOR (Homo sapiens;enterobacteria phage t4) | 7tm_1 | ||
6aji | AY6 | Rimonabant (DB06155) | Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite.... | DRUG EXPORTERS OF THE RND SUPERFAMILY-LIKE PROTEIN,ENDOLYSIN (Mycobacterium smegmatis (strain atcc 700084 / mc(2)155);enterobacteria phage t4) | MMPLPhage_lysozyme | ||
6cm4 | 8NU | Risperidone (DB00734) | Risperidone is a second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression. | D(2) DOPAMINE RECEPTOR, ENDOLYSIN CHIMERA (Homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
6j20 | GBQ | Aprepitant (DB00673) | Aprepitant is a substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. | SUBSTANCE-P RECEPTOR,ENDOLYSIN (Homo sapiens;enterobacteria phage t4) | 7tm_1 | ||
6k41 | CZX | Dexmedetomidine (DB00633) | Dexmedetomidine is an alpha-2 agonist used for sedation during various procedures. | ALPHA-2A ADRENERGIC RECEPTOR,ENDOLYSIN,ALPHA-2B ADRENERGIC RECEPTOR,ALPHA-2B ADRENERGIC RECEPTOR (Homo sapiens;mus musculus;bos taurus;enterobacteria phage rb59) | 7tm_1 | ||
6luq | GMJ | Haloperidol (DB00502) | Haloperidol is an antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. | CHIMERA OF D(2) DOPAMINE RECEPTOR AND ENDOLYSIN (Homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
6mxt | K5Y | Salmeterol (DB00938) | Salmeterol is a long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. | ENDOLYSIN, BETA-2 ADRENERGIC RECEPTOR CHIMERA (Enterobacteria phage t4;homo sapiens;lama glama) | 7tm_1Phage_lysozyme | ||
6vms | 08Y | Bromocriptine (DB01200) | Bromocriptine is a dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. | ENDOLYSIN,D(2) DOPAMINE RECEPTOR,D(2) DOPAMINE RECEPTOR (Rattus norvegicus;homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
6wjc | OIN | Atropine (DB00572) | Atropine is a muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. | MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN FUSION (Homo sapiens;enterobacteria phage t4;dendroaspis angusticeps) | 7tm_1Phage_lysozyme | ||
7bu6 | E5E | Norepinephrine (DB00368) | Norepinephrine is a sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. | ENDOLYSIN,ENDOLYSIN,ENDOLYSIN,BETA-1 ADRENERGIC RECEPTOR CHIMERA (Enterobacteria phage t4;homo sapiens;camelidae mixed library) | Phage_lysozyme | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |