LIST OF BINDING INTERFACES for query 'DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE' in category 'PROTEIN NAME'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
1j3j	CP6	Pyrimethamine (DB00205)	Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.	BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (Plasmodium falciparum)	DHFR_1	1J3J_A_CP6A609	Details
2bl9	CP6	Pyrimethamine (DB00205)	Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.	DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (Plasmodium vivax)	DHFR_1	2BL9_A_CP6A1240	Details
3nrr	D16	Raltitrexed (DB00293)	Raltitrexed is a folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer.	DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (Babesia bovis)	DHFR_1 Thymidylat_synt	3NRR_A_D16A520  3NRR_A_D16A530	Details
3qfx	CP6	Pyrimethamine (DB00205)	Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.	BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (Trypanosoma brucei rhodesiense)	DHFR_1	3QFX_A_CP6A602	Details
6aog	CP6	Pyrimethamine (DB00205)	Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.	BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (Toxoplasma gondii)	Thymidylat_synt	6AOG_A_CP6A704	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["1j3j","CP6","Pyrimethamine (DB00205)","Plasmodium falciparum","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","DHFR_1"],["2bl9","CP6","Pyrimethamine (DB00205)","Plasmodium vivax","DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","DHFR_1"],["3nrr","D16","Raltitrexed (DB00293)","Babesia bovis","DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","DHFR_1;Thymidylat_synt"],["3qfx","CP6","Pyrimethamine (DB00205)","Trypanosoma brucei rhodesiense","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","DHFR_1"],["6aog","CP6","Pyrimethamine (DB00205)","Toxoplasma gondii","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","Thymidylat_synt"]]