
Select categories:
Ligand ID | Drug | DrugBank ID | Indication | View |
---|---|---|---|---|
010 | DB06770 | Benzyl alcohol | Benzyl alcohol is an antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older. | |
017 | DB01264 | Darunavir | Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. | |
032 | DB08881 | Vemurafenib | Vemurafenib is a kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. | |
06X | DB00381 | Amlodipine | Amlodipine is a calcium channel blocker used to treat hypertension and angina. | |
08D | DB01015 | Sulfamethoxazole | Sulfamethoxazole is an oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. | |
08H | DB00404 | Alprazolam | Alprazolam is a triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. | |
08J | DB00683 | Midazolam | Midazolam is a short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. | |
08Y | DB01200 | Bromocriptine | Bromocriptine is a dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. | |
09L | DB09074 | Olaparib | Olaparib is a chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy. | |
0HK | DB01409 | Tiotropium | Tiotropium is a long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). | |
0JM | DB00578 | Carbenicillin | Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function. | |
0LI | DB08901 | Ponatinib | Ponatinib is a kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML). | |
0RM | DB01603 | Meticillin | One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection. | |
0RN | DB09324 | Sulbactam | Sulbactam is an beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. | |
0RV | DB00760 | Meropenem | Meropenem is a carbapenem antibiotic used to treat a wide variety of infections in the body. | |
0WM | DB08916 | Afatinib | Afatinib is an antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy. | |
0WO | DB00713 | Oxacillin | Oxacillin is a penicillin antibiotic used to treat a number of susceptible bacterial infections. | |
115 | DB01095 | Fluvastatin | Fluvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. | |
116 | DB00439 | Cerivastatin | Cerivastatin is a statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events. | |
117 | DB01076 | Atorvastatin | Atorvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. | |
142 | DB00190 | Carbidopa | Carbidopa is a dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms. | |
15M | DB00905 | Bimatoprost | Bimatoprost is a prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. | |
15U | DB00278 | Argatroban | Argatroban is a synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use. | |
16A | DB01718 | Cetrimonium | Cetrimonium is a compound that can be used as a topical antiseptic. | |
1C6 | DB00338 | Omeprazole | Omeprazole is a proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. | |
1C9 | DB11963 | Dacomitinib | Dacomitinib is a medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution. | |
1E8 | DB09053 | Ibrutinib | Ibrutinib is an antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia. | |
1FL | DB00861 | Diflunisal | Diflunisal is an NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis. | |
1KX | DB01048 | Abacavir | Abacavir is an antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV. | |
1LD | DB01099 | Flucytosine | Flucytosine is an antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus. | |
1LT | DB12015 | Alpelisib | Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110α , which is the catalytic subunit of PI3K, a lipid... | |
1N1 | DB01254 | Dasatinib | Dasatinib is a tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy. | |
1PQ | DB01087 | Primaquine | Primaquine is an antimalarial indicated to prevent relapse of vivax malaria. | |
1PT | DB00526 | Oxaliplatin | Oxaliplatin is a platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer. | |
1QL | DB01331 | Cefoxitin | Cefoxitin is a semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection. | |
1RG | DB00303 | Ertapenem | Ertapenem is a carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms. | |
1UN | DB00220 | Nelfinavir | Nelfinavir is a viral protease inhibitor used in the treatment of HIV infection. | |
1W8 | DB06590 | Ceftaroline fosamil | Ceftaroline fosamil is an antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. | |
1WE | DB01576 | Dextroamphetamine | Dextroamphetamine is a sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. | |
1YN | DB01167 | Itraconazole | Itraconazole is an antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. | |
20J | DB01119 | Diazoxide | Diazoxide is a non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions. | |
210 | DB00282 | Pamidronic acid | Pamidronic acid is a bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions. | |
211 | DB13747 | Trolamine | Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine... | |
212 | DB00630 | Alendronic acid | Alendronic acid is a bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. | |
21B | DB00540 | Nortriptyline | Nortriptyline is a tricyclic antidepressant used in the treatment of depression. | |
225 | DB01023 | Felodipine | Felodipine is a calcium channel blocker used to treat hypertension. | |
268 | DB11304 | Phenoxyethanol | Phenoxyethanol is an antiseptic used as a hand disinfectant or preservative in medications. | |
27J | DB11478 | Zeranol | Zeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. It is 3-4x... | |
27R | DB00963 | Bromfenac | Bromfenac is an NSAID used to treat postoperative pain and inflammation of the eye. | |
29E | DB00476 | Duloxetine | Duloxetine is a serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. | |
29J | DB06700 | Desvenlafaxine | Desvenlafaxine is an antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. | |
29Q | DB00579 | Mazindol | Mazindol is a sympathomimetic used to treat obesity in combination with lifestyle modifications. | |
29S | DB06401 | Bazedoxifene | Bazedoxifene is a selective estrogen receptor modulator (SERM) used to treat moderate to severe vasomotor symptoms in menopause and osteoporosis alone or in combination with conjugated estrogens. | |
2AL | DB11100 | Allantoin | Allantoin is an ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns. | |
2DI | DB00900 | Didanosine | Didanosine is a reverse transcriptase inhibitor used to treat HIV. | |
2GM | DB00320 | Dihydroergotamine | Dihydroergotamine is an ergot alkaloid used in the acute treatment of migraine headache and cluster headache. | |
2K2 | DB06595 | Midostaurin | Midostaurin is an antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). | |
2KW | DB12301 | Doravirine | Doravirine is a non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections. | |
2MN | DB00916 | Metronidazole | Metronidazole is a nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. | |
2PM | DB01075 | Diphenhydramine | Diphenhydramine is a H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. | |
2PP | DB00313 | Valproic acid | Valproic acid is an anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. | |
2Q2 | DB13180 | Gluconic acid | Gluconic Acid is an electrolyte supplement used in total parenteral nutrition. | |
2R9 | DB11586 | Asunaprevir | Asunaprevir is an NS3 protease inhibitor used to treat hepatitis C genotype 1b. | |
2RC | DB12010 | Fostamatinib | Fostamatinib is a spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment. | |
2SJ | DB15534 | Colchiceine | Colchiceine is one of several metabolites of the anti-gout medication colchicine. | |
2TA | DB12500 | Fedratinib | Fedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis.[A183176,L8090] It is an anilinopyrimidine derivative. Fedratinib was... | |
2YQ | DB11760 | Talazoparib | Talazoparib is a poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer. | |
308 | DB00915 | Amantadine | Amantadine is a medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications. | |
30B | DB06290 | Simeprevir | Simeprevir is a direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. | |
30Z | DB00179 | Masoprocol | A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in... | |
356 | DB08882 | Linagliptin | Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. | |
36M | DB14177 | Propylparaben | Propylparaben is used in allergenic testing. | |
377 | DB01043 | Memantine | Memantine is an NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's. | |
3BV | DB08889 | Carfilzomib | Carfilzomib is a proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma. | |
3C0 | DB11315 | Methscopolamine | Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The... | |
3CJ | DB00550 | Propylthiouracil | Propylthiouracil is a thiourea antithyroid agent used to treat hyperthyroidism. | |
3EW | DB11689 | Selumetinib | Selumetinib is a MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN). | |
3JD | DB11793 | Niraparib | Niraparib is a poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy. | |
3JW | DB11817 | Baricitinib | Baricitinib is a Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. | |
3MI | DB11644 | Tafamidis | Tafamidis is a medication used to treat transthyretin-mediated amyloidosis. | |
3NF | DB11102 | N-acetyltyrosine | N-acetyltyrosine is an amino acid used in total parenteral nutrition. | |
3QB | DB01627 | Lincomycin | Lincomycin is an antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate. | |
3T5 | DB14669 | Betamethasone phosphate | Betamethasone phosphate is a fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions. | |
3TC | DB00709 | Lamivudine | Lamivudine is a reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. | |
3WF | DB00977 | Ethinylestradiol | Ethinylestradiol is an estradiol used as a contraceptive. | |
40L | DB09054 | Idelalisib | Idelalisib is an antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). | |
41X | DB00234 | Reboxetine | Reboxetine is a drug used for the acute treatment of major depression and for maintenance therapy of depression. | |
478 | DB00701 | Amprenavir | Amprenavir is a protease inhibitor used to treat HIV infection. | |
486 | DB00834 | Mifepristone | Mifepristone is a cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation. | |
4AP | DB06637 | Dalfampridine | Dalfampridine is a potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS). | |
4AX | DB00260 | Cycloserine | Cycloserine is a broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI). | |
4CH | DB13154 | Parachlorophenol | Parachlorophenol is an antibacterial agent used to prevent infections in root canals. | |
4D6 | DB12107 | Vaborbactam | Vaborbactam is a beta lactamase inhibitor used to treat complicated urinary tract infections. | |
4DW | DB00642 | Pemetrexed | Pemetrexed is a folate analog used to treat mesothelioma and non-small cell lung cancer. | |
4DY | DB06774 | Capsaicin | Capsaicin is a topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. | |
4KO | DB00274 | Cefmetazole | Cefmetazole is a cephalosporin antibiotic used to treat a variety of bacterial infections. | |
4KS | DB09516 | Mequinol | Mequinol is a topical agent used in combination with tretinoin to treat solar lentigines. | |
4MK | DB09063 | Ceritinib | Ceritinib is an antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib. | |
4PZ | DB01213 | Fomepizole | Fomepizole is an inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. | |
4TX | DB01241 | Gemfibrozil | Gemfibrozil is a lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. | |
5AE | DB00928 | Azacitidine | Azacitidine is a pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome. | |
5CH | DB01628 | Etoricoxib | Etoricoxib is a selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis. | |
5FW | DB01064 | Isoprenaline | Isoprenaline is a catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. | |
5OG | DB05015 | Belinostat | Belinostat is a histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). | |
5P8 | DB12130 | Lorlatinib | Lorlatinib is an anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. | |
5RL | DB00714 | Apomorphine | Apomorphine is a morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease. | |
5SF | DB12147 | Erdafitinib | Erdafitinib is a fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma. | |
5WQ | DB01045 | Rifampicin | Rifampicin is an antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. | |
62W | DB00742 | Mannitol | Mannitol is a sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. | |
64Z | DB14183 | Geraniol | Geraniol is a monoterpene that is found within many essential oils of fruits, vegetables, and herbs including rose oil, citronella, lemongrass, lavender, and other aromatic plants. It is emitted from... | |
657 | DB00740 | Riluzole | Riluzole is a glutamate antagonist used to treat amyotrophic lateral sclerosis. | |
65B | DB06414 | Etravirine | Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. | |
68H | DB13139 | Levosalbutamol | Levosalbutamol is a beta-2 adrenergic receptor agonist used to treat COPD and asthma. | |
68P | DB01175 | Escitalopram | Escitalopram is a selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). | |
69Q | DB13874 | Enasidenib | Enasidenib is an isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. | |
6E2 | DB12483 | Copanlisib | Copanlisib is a medication used to treat relapsed follicular lymphoma who have attempted at least two other treatments. | |
6EL | DB01041 | Thalidomide | Thalidomide is a medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum. | |
6GY | DB12267 | Brigatinib | Brigatinib is an anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. | |
6K9 | DB08871 | Eribulin | Eribulin is a microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma. | |
6LH | DB06795 | Mafenide | Mafenide is an antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. | |
6T0 | DB00724 | Imiquimod | Imiquimod is a toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata. | |
6U9 | DB00393 | Nimodipine | Nimodipine is a calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. | |
6UB | DB09237 | Levamlodipine | Levamlodipine is a calcium channel blocker used to treat hypertension. | |
6UV | DB00563 | Methotrexate | Methotrexate is an antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis. | |
6V8 | DB09570 | Ixazomib | Ixazomib is a monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already. | |
6ZP | DB08883 | Perampanel | Perampanel is a non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy. | |
6ZV | DB12001 | Abemaciclib | Abemaciclib is a medication used to treat HR+ HER2- advanced or metastatic breast cancer. | |
6ZZ | DB11730 | Ribociclib | Ribociclib is a kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer. | |
715 | DB01261 | Sitagliptin | Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. | |
71R | DB11512 | Dihydrostreptomycin | Dihydrostreptomycin is an antibiotic. | |
7A9 | DB00377 | Palonosetron | Palonosetron is a serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. | |
7HP | DB00437 | Allopurinol | Allopurinol is a xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies. | |
7KP | DB11263 | Polydatin | Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin... | |
7V7 | DB00813 | Fentanyl | Fentanyl is an opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. | |
803 | DB00227 | Lovastatin | Lovastatin is an HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke. | |
84D | DB13270 | Dibekacin | Dibekacin is an aminoglycoside antibiotic marketed in Japan . | |
8CV | DB00914 | Phenformin | A biguanide hypoglycemic agent with actions and uses similar to those of metformin. Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often... | |
8MO | DB00553 | Methoxsalen | Methoxsalen is a furocoumarin used to treat psoriasis and vitiligo. | |
8N6 | DB01132 | Pioglitazone | Pioglitazone is a thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. | |
8NU | DB00734 | Risperidone | Risperidone is a second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression. | |
8PR | DB00715 | Paroxetine | Paroxetine is a selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. | |
8QP | DB00749 | Etodolac | Etodolac is an NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain. | |
8W5 | DB01222 | Budesonide | Budesonide is a corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. | |
8YF | DB01598 | Imipenem | Imipenem is a carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. | |
911 | DB01077 | Etidronic acid | Etidronic acid is a bisphosphonate drug that prevents osteoclastic bone resorption; used for the prevention and treatment of osteoporosis. | |
95E | DB00330 | Ethambutol | Ethambutol is an antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB). | |
95Z | DB01296 | Glucosamine | Glucosamine is a common ingredient in nutritional supplements used for the relief of joint pain. | |
970 | DB11457 | Rotenone | Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also... | |
9CR | DB00523 | Alitretinoin | Alitretinoin is a vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis. | |
9DC | DB06782 | Dimercaprol | Dimercaprol is a chelating agent used as an antidote to arsenic, gold, and mercury poisoning, as well as acute lead poisoning in combination with edetate calcium disodium. | |
9EG | DB11155 | Triclocarban | Triclocarban is an antibacterial agent used in liquid soaps and body washes. | |
9EP | DB00456 | Cefalotin | Cefalotin is a broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract. | |
9F2 | DB01212 | Ceftriaxone | Ceftriaxone is a broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract. | |
9HB | DB08908 | Dimethyl fumarate | Dimethyl fumarate is a medication used to treat patients with the relapsing-remitting form of multiple sclerosis. | |
9KL | DB09214 | Dexketoprofen | Dexketoprofen is an NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain. | |
9PL | DB01085 | Pilocarpine | Pilocarpine is a muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy. | |
9RA | DB00307 | Bexarotene | Bexarotene is a retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. | |
9SC | DB01238 | Aripiprazole | Aripiprazole is an atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. | |
9TP | DB00444 | Teniposide | Teniposide is a cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia. | |
9UQ | DB00357 | Aminoglutethimide | Aminoglutethimide is an adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome. | |
9V2 | DB00593 | Ethosuximide | Ethosuximide is an anticonvulsant used to treat petit mal seizures. | |
9WT | DB01413 | Cefepime | Cefepime is a fourth-generation cephalosporin antibiotic used in the treatment of various bacterial infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections. | |
9Y6 | DB14184 | Cinnamaldehyde | Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus... | |
A0B | DB13911 | Phloxine b | Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to... | |
A26 | DB08880 | Teriflunomide | Teriflunomide is a pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. | |
A4Z | DB13346 | Bufexamac | Bufexamac is an NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. | |
A9L | DB05676 | Apremilast | Apremilast is a non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis. | |
AB1 | DB01601 | Lopinavir | Lopinavir is an HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. | |
ABU | DB02530 | Gamma-aminobutyric acid | The most common inhibitory neurotransmitter in the central nervous system. | |
AC2 | DB00787 | Acyclovir | Acyclovir is a guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. | |
ACA | DB00513 | Aminocaproic acid | Aminocaproic acid is an antifibrinolytic agent used to induce clotting postoperatively. | |
ACH | DB03128 | Acetylcholine | Acetylcholine is a parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. | |
AEG | DB09352 | Hydroxyamphetamine | Hydroxyamphetamine is an indirectly acting sympathomimetic agent producing mydriasis for diagnostic purposes. | |
AER | DB05812 | Abiraterone | Abiraterone is an antiandrogen used in the treatment of prostate cancer. | |
AGG | DB00775 | Tirofiban | Tirofiban is a platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome. | |
AIC | DB00415 | Ampicillin | Ampicillin is a penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. | |
AIN | DB00945 | Acetylsalicylic acid | Aspirin is a salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. | |
AJM | DB01426 | Ajmaline | Ajmaline is an antiarrhythmic used to manage a variety of forms of tachycardias. | |
AKN | DB00479 | Amikacin | Amikacin is an aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria. | |
ALE | DB00668 | Epinephrine | Epinephrine is a hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. | |
AM2 | DB04626 | Apramycin | Apramycin is an aminoglycoside antibiotic for veterinary use that is used to treat infections in animals. | |
AMH | DB00302 | Tranexamic acid | Tranexamic acid is an antifibrinolytic used to reduce or prevent hemorrhagic episodes, especially in the context of hyperfibrinolytic disorders. | |
AMJ | DB06218 | Lacosamide | Lacosamide is an antiepileptic drug used to treat partial onset seizures in adults. | |
AMR | DB00594 | Amiloride | Amiloride is a pyrizine compound used to treat hypertension and congestive heart failure. | |
ANW | DB01025 | Amlexanox | Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent... | |
AOQ | DB01117 | Atovaquone | Atovaquone is an antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria. | |
AQ4 | DB00530 | Erlotinib | Erlotinib is an EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers. | |
AR3 | DB00987 | Cytarabine | Cytarabine is a pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia. | |
ASR | DB03006 | Arsanilic acid | An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem] | |
ASW | DB00276 | Amsacrine | Amsacrine is a cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents. | |
AWY | DB06594 | Agomelatine | Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine... | |
AXI | DB06626 | Axitinib | Axitinib is an oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy. | |
AY6 | DB06155 | Rimonabant | Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite.... | |
AZ1 | DB00548 | Azelaic acid | Azelaic acid is a saturated dicarboxylic acid used to treat mild to moderate acne vulgaris. | |
AZM | DB00819 | Acetazolamide | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | |
AZR | DB00355 | Aztreonam | Aztreonam is a beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. | |
AZZ | DB00495 | Zidovudine | Zidovudine is a dideoxynucleoside used in the treatment of HIV infection. | |
B1T | DB04813 | Bithionol | Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the... | |
B40 | DB01577 | Metamfetamine | Metamfetamine is a sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity. | |
B49 | DB01268 | Sunitinib | Sunitinib is a receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). | |
B4O | DB01188 | Ciclopirox | Ciclopirox is a broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients. | |
BA0 | DB15035 | Zanubrutinib | Zanubrutinib is a kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy. | |
BAX | DB00398 | Sorafenib | Sorafenib is a kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma. | |
BBI | DB01118 | Amiodarone | Amiodarone is a class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. | |
BCZ | DB06614 | Peramivir | Peramivir is an intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days. | |
BEP | DB01244 | Bepridil | A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts... | |
BER | DB04115 | Berberine | An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal... | |
BFQ | DB00710 | Ibandronate | Ibandronate is a bisphosphonate used to treat osteoporosis in postmenopausal women. | |
BHA | DB00233 | Aminosalicylic acid | Aminosalicylic acid is an aminosalicylate drug used to induce remission in ulcerative colitis. | |
BJX | DB00912 | Repaglinide | Repaglinide is a antihyperglycemic used to improve glycemic control in diabetes. | |
BLM | DB00290 | Bleomycin | Bleomycin is a chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others. | |
BLQ | DB01014 | Balsalazide | Balsalazide is an aminosalicylate used to treat ulcerative colitis. | |
BO2 | DB00188 | Bortezomib | Bortezomib is a proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies. | |
BO3 | DB11326 | Boric acid | Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. Boric acid is typically utilized in industrial processing and manufacturing,... | |
BQ1 | DB08903 | Bedaquiline | Bedaquiline is a diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB). | |
BRL | DB00412 | Rosiglitazone | Rosiglitazone is a thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. | |
BS4 | DB09355 | Sulfabenzamide | Sulfabenzamide is a sulfonamide antibacterial used as an ingredient in various topical and vaginal preparations to treat certain infections, but has been discontinued by the FDA. | |
BUW | DB00392 | Profenamine | Profenamine is an antidyskinetic phenothiazine used to treat the symptoms of Parkinson's disease. | |
BVD | DB03312 | Brivudine | Brivudine is a drug used to treat herpes zoster. | |
BZ1 | DB01194 | Brinzolamide | Brinzolamide is a carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. | |
BZM | DB00676 | Benzyl benzoate | Benzyl benzoate is a topical treatment for scabies and lice. | |
C04 | DB00671 | Cefixime | Cefixime is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. | |
C3D | DB06202 | Lasofoxifene | Lasofoxifene is a non-steroidal 3rd generation selective estrogen receptor modulator (SERM) that selectively binds to both ERα and ERβ with high affinity. It is a naphthalene derivative marketed for prevention... | |
C41 | DB09026 | Aliskiren | Aliskiren is a direct renin inhibitor used to manage hypertension. | |
C5U | DB01115 | Nifedipine | Nifedipine is a dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. | |
C6F | DB12141 | Gilteritinib | Gilteritinib is an AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia. | |
C7H | DB00434 | Cyproheptadine | Cyproheptadine is a combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome. | |
C9F | DB00343 | Diltiazem | Diltiazem is a calcium channel blocker used to treat hypertension and to manage chronic stable angina. | |
CA4 | DB04839 | Cyproterone acetate | Cyproterone acetate is a steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer | |
CBE | DB04657 | Carboxin | A systemic agricultural fungicide and seed treatment agent. | |
CBL | DB00291 | Chlorambucil | Chlorambucil is a chemotherapy agent used in the management of chronic lymphocytic leukemia and malignant lymphomas. | |
CC9 | DB11672 | Curcumin | Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in Curcuma xanthorrhiza oil. It is a highly pleiotropic molecule that exhibits antibacterial,... | |
CCE | DB00411 | Carbamoylcholine | Carbachol is a direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. | |
CCS | DB04339 | Carbocisteine | Carbocisteine is a expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity. | |
CDC | DB12153 | Citicoline | Citicoline is an endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects. | |
CDX | DB00380 | Dexrazoxane | Dexrazoxane is a cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer. | |
CE3 | DB00493 | Cefotaxime | Cefotaxime is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. | |
CE9 | DB06811 | Polidocanol | Polidocanol is a sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity. | |
CEL | DB00482 | Celecoxib | Celecoxib is an NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. | |
CFB | DB00631 | Clofarabine | Clofarabine is a purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old. | |
CFF | DB00201 | Caffeine | Caffeine is a stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. | |
CGE | DB00758 | Clopidogrel | Clopidogrel is an antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. | |
CHC | DB05990 | Obeticholic acid | Obeticholic acid is a bile acid analog and farnesoid X receptor agonist used to treat primary biliary cholangitis in adult patients with inadequate clinical response or intolerance to UDCA. | |
CHD | DB02659 | Cholic acid | Cholic Acid is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. | |
CHZ | DB04816 | Dantron | Dantron is a drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx. | |
CIA | DB00820 | Tadalafil | Tadalafil is a phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. | |
CIL | DB01597 | Cilastatin | Cilastatin is a renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections. | |
CL6 | DB00257 | Clotrimazole | Clotrimazole is a topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis. | |
CL8 | DB07565 | Chloramphenicol succinate | Chloramphenicol succinate is a broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains. | |
CL9 | DB00242 | Cladribine | Cladribine is a purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs. | |
CLM | DB00446 | Chloramphenicol | Chloramphenicol is a broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. | |
CLQ | DB00608 | Chloroquine | Chloroquine is an antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis. | |
CLT | DB06819 | Phenylbutyric acid | Phenylbutyric acid is an agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy. | |
CLU | DB00575 | Clonidine | Clonidine is an alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. | |
CLW | DB00356 | Chlorzoxazone | Chlorzoxazone is a drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions. | |
CLY | DB01190 | Clindamycin | Clindamycin is a lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria. | |
CMU | DB09343 | Tipiracil | Tipiracil is a thymidine phosphorylase inhibitor used as an adjunct treatment of adult patients with certain types of gastric or colorectal malignancies. | |
COM | DB09110 | Coenzyme m | Coenzyme M is a uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract. | |
COX | DB00580 | Valdecoxib | Valdecoxib is a COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. | |
CP0 | DB00762 | Irinotecan | Irinotecan is an antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum. | |
CP6 | DB00205 | Pyrimethamine | Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria. | |
CPF | DB00537 | Ciprofloxacin | Ciprofloxacin is a second generation fluoroquinolone used to treat various susceptible bacterial infections. | |
CPT | DB00515 | Cisplatin | Cisplatin is a platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. | |
CQA | DB00613 | Amodiaquine | Amodiaquine is an antimalarial drug. | |
CQL | DB04815 | Clioquinol | Clioquinol is an antifungal cream used to treat a variety of fungal infections. | |
CTC | DB09093 | Chlortetracycline | Chlortetracycline is the first tetracycline antibiotic most commonly used for veterinary purposes. | |
CTX | DB00675 | Tamoxifen | Tamoxifen is a selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women. | |
CTY | DB01211 | Clarithromycin | Clarithromycin is a macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. | |
CU9 | DB01336 | Metocurine | Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant. Patients on chronic anticonvulsant drugs are relatively resistant to metocurine. | |
CVD | DB01136 | Carvedilol | Carvedilol is a non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. | |
CVI | DB00406 | Gentian violet cation | Gentian Violet is an antiseptic violet dye used to prevent various infections, including fungal and bacterial infections. | |
CWB | DB00889 | Granisetron | Granisetron is a 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. | |
CXQ | DB00245 | Benzatropine | Benzatropine is an anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia. | |
CXX | DB01242 | Clomipramine | Clomipramine is a tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder. | |
CYZ | DB00606 | Cyclothiazide | As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides... | |
CZE | DB00341 | Cetirizine | Cetirizine is a selective Histamine-1 antagonist drug used in allergic rhinitis and chronic urticaria. | |
CZX | DB00633 | Dexmedetomidine | Dexmedetomidine is an alpha-2 agonist used for sedation during various procedures. | |
D16 | DB00293 | Raltitrexed | Raltitrexed is a folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer. | |
D8Z | DB06697 | Artemether | Artemether is an antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. | |
D95 | DB09274 | Artesunate | Artesunate is artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria. | |
DAH | DB01235 | Levodopa | Levodopa is a dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. | |
DB8 | DB06616 | Bosutinib | Bosutinib is an antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments. | |
DCF | DB00552 | Pentostatin | Pentostatin is an adenosine deaminase inhibitor used to treat hairy cell leukemia. | |
DE3 | DB11282 | Diethyltoluamide | Diethyltoluamide is an insect repellant, also known as DEET. | |
DEQ | DB04209 | Dequalinium | Dequalinium is a quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat that has been studied in the treatment of vaginal candidiasis. | |
DES | DB00255 | Diethylstilbestrol | A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report... | |
DEX | DB01234 | Dexamethasone | Dexamethasone is a glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. | |
DGJ | DB05018 | Migalastat | Migalastat is an alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant. | |
DGX | DB00390 | Digoxin | Digoxin is a cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. | |
DHL | DB00847 | Cysteamine | Cysteamine is a cystine depleting agent used to treat the effects of cystinosis. | |
DIF | DB00586 | Diclofenac | Diclofenac is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. | |
DLU | DB08930 | Dolutegravir | Dolutegravir is an antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents. | |
DM1 | DB00694 | Daunorubicin | Daunorubicin is an anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia. | |
DM2 | DB00997 | Doxorubicin | Doxorubicin is a medication used to treat various cancers and Kaposi's Sarcoma. | |
DM5 | DB01177 | Idarubicin | Idarubicin is an anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults. | |
DME | DB01245 | Decamethonium | Decamethonium is used in anesthesia to cause paralysis. It is a short acting depolarizing muscle relaxant. It is similar to acetylcholine and acts as a partial agonist of the nicotinic... | |
DOL | DB01764 | Dalfopristin | Dalfopristin is an antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes. | |
DP0 | DB00280 | Disopyramide | Disopyramide is a class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. | |
DR7 | DB01072 | Atazanavir | Atazanavir is an antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. | |
DSF | DB01189 | Desflurane | Desflurane is a general inhalation anesthetic for inpatient and outpatient surgery in adults. | |
DSM | DB01151 | Desipramine | Desipramine is a tricyclic antidepressant used in the treatment of depression. | |
DX2 | DB00384 | Triamterene | Triamterene is a potassium-sparing diuretic used in the treatment of edema and in the management of hypertension. | |
DX4 | DB00352 | Tioguanine | Tioguanine is a purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias. | |
DXF | DB01112 | Cefuroxime | Cefuroxime is a cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo. | |
DXT | DB00254 | Doxycycline | Doxycycline is a tetracycline antibiotic used to treat a wide variety of bacterial infections. | |
DZP | DB00829 | Diazepam | Diazepam is a long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. | |
E53 | DB01590 | Everolimus | Everolimus is a mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies. | |
E5E | DB00368 | Norepinephrine | Norepinephrine is a sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. | |
E6L | DB06237 | Avanafil | Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used to treat erectile dysfunction. | |
EAA | DB00903 | Etacrynic acid | Etacrynic acid is a diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease. | |
EAL | DB09477 | Enalaprilat | Enalaprilat is an antihypertensive agent used for the management of hypertension when oral therapy is not practical. | |
EDN | DB14189 | Ethylenediamine | Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products. It is also used as an excipient in many pharmacological... | |
EDP | DB00599 | Thiopental | Thiopental is a barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. | |
EDR | DB01010 | Edrophonium | Edrophonium is a cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis. | |
EDS | DB12615 | Plazomicin | Plazomicin is an aminoglycoside antibiotic used to treat complicated urinary tract infections. | |
EFZ | DB00625 | Efavirenz | Efavirenz is a non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. | |
ELV | DB09101 | Elvitegravir | Elvitegravir is an antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. | |
EMH | DB11363 | Alectinib | Alectinib is a kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. | |
ERG | DB04038 | Ergosterol | A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS... | |
ERM | DB00696 | Ergotamine | Ergotamine is a alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. | |
ERY | DB00199 | Erythromycin | Erythromycin is a macrolide antibiotic used to treat and prevent a variety of bacterial infections. | |
ESL | DB04573 | Estriol | Estriol is a weak estrogen used to treat vaginal dryness and estrogen deficiency conditions, such as vaginitis and vulvar itching. | |
EST | DB00783 | Estradiol | Estradiol is an estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate. | |
ETS | DB00869 | Dorzolamide | Dorzolamide is a carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. | |
ETV | DB00879 | Emtricitabine | Emtricitabine is a nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. | |
EUG | DB14188 | Isoeugenol | Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic... | |
EUI | DB05239 | Cobimetinib | Cobimetinib is an antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma. | |
EV1 | DB01113 | Papaverine | Papaverine is an alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms". | |
EVP | DB00773 | Etoposide | Etoposide is a podophyllotoxin derivative used to treat testicular and small cell lung tumors. | |
EXM | DB00990 | Exemestane | Exemestane is an aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen. | |
F0F | DB04896 | Milnacipran | Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder. | |
F1U | DB00193 | Tramadol | Tramadol is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. | |
F5A | DB13873 | Fenofibric acid | Fenofibric acid is a fibrate used to treat severe hypertriglyceridemia, primary hypercholesterolemia, or mixed dyslipidemia. | |
F5O | DB11979 | Elagolix | Elagolix is a gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis. | |
F9E | DB01610 | Valganciclovir | Valganciclovir is an antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS). | |
F9R | DB01396 | Digitoxin | Digitoxin is a cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. | |
FBI | DB01098 | Rosuvastatin | Rosuvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. | |
FBX | DB04953 | Ezogabine | Ezogabine is an antiepileptic agent used as an adjuvant treatment of partial-onset seizures. | |
FCN | DB00828 | Fosfomycin | Fosfomycin is a broad spectrum antibiotic used to treat uncomplicated urinary tract infections. | |
FFO | DB11596 | Levoleucovorin | Levoleucovorin is a folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. | |
FGT | DB04824 | Phenolphthalein | Phenolphthalein is a drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures. | |
FI8 | DB08874 | Fidaxomicin | Fidaxomicin is a macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection. | |
FIT | DB01216 | Finasteride | Finasteride is an antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase. | |
FJQ | DB01007 | Tioconazole | Tioconazole is an imidazole antifungal used to treat vulvovaginal candidiasis. | |
FK5 | DB00864 | Tacrolimus | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | |
FL7 | DB00690 | Flurazepam | Flurazepam is a long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. | |
FLF | DB02266 | Flufenamic acid | Flufenamic acid is an analgesic drug used to relieve pain associated with rheumatoid diseases. | |
FLP | DB00712 | Flurbiprofen | Flurbiprofen is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. | |
FLU | DB00693 | Fluorescein | Fluorescein is a dye used in angiography or angioscopy of the iris and retina. | |
FMM | DB01259 | Lapatinib | Lapatinib is an antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments. | |
FO9 | DB00927 | Famotidine | Famotidine is a histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. | |
FRD | DB00182 | Amphetamine | Amphetamine is a CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). | |
FUA | DB02703 | Fusidic acid | Fusidic acid is a topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. | |
FUN | DB00695 | Furosemide | Furosemide is a loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. | |
FUR | DB00614 | Furazolidone | Furazolidone is a drug for the treatment of infectious diarrhea. | |
FVK | DB13781 | Xamoterol | Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but... | |
FVS | DB00947 | Fulvestrant | Fulvestrant is an estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-. | |
FVT | DB00855 | Aminolevulinic acid | Aminolevulinic acid is a porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma. | |
FVX | DB00176 | Fluvoxamine | Fluvoxamine is a selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. | |
FY5 | DB04574 | Estrone sulfate | Estrone sulfate is an estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders. | |
FYG | DB09060 | Avibactam | Avibactam is a non-β-lactam β-lactamase inhibitor used in combination with ceftazidime for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and hospital or ventilator-acquired pneumonia. | |
FYP | DB01205 | Flumazenil | Flumazenil is a benzodiazepine antagonist that is used for the complete or partial reversal of the sedative effects caused by benzodiazepines in various clinical settings, such as induced general anesthesia for diagnostic and therapeutic procedures. | |
G3C | DB00800 | Fenoldopam | Fenoldopam is a dopamine D1 receptor agonist used for the short term management of hypertension. | |
G65 | DB11526 | Masitinib | Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the... | |
G6L | DB00413 | Pramipexole | Pramipexole is a non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS). | |
GA2 | DB01004 | Ganciclovir | Ganciclovir is a DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. | |
GAW | DB09048 | Netupitant | Netupitant is an antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy. | |
GBM | DB01016 | Glyburide | Glyburide is a sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. | |
GBN | DB00996 | Gabapentin | Gabapentin is an anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. | |
GBQ | DB00673 | Aprepitant | Aprepitant is a substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. | |
GCZ | DB01120 | Gliclazide | Gliclazide is a sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. | |
GD4 | DB00197 | Troglitazone | Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone. | |
GEO | DB00441 | Gemcitabine | Gemcitabine is a nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer. | |
GG2 | DB06605 | Apixaban | Apixaban is an anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery. | |
GM4 | DB00652 | Pentazocine | Pentazocine is an analgesic used to treat moderate to severe pain. | |
GMJ | DB00502 | Haloperidol | Haloperidol is an antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. | |
GMR | DB00222 | Glimepiride | Glimepiride is a sulfonylurea drug used to treat type 2 diabetes mellitus. | |
GNT | DB00674 | Galantamine | Galantamine is a cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. | |
GW6 | DB08906 | Fluticasone furoate | Fluticasone furoate is an inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis. | |
GZX | DB04845 | Ixabepilone | Ixabepilone is a microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines. | |
H3P | DB00756 | Hexachlorophene | Hexachlorophene is a chlorinated bisphenol antiseptic used as a surgical scrub and skin cleanser. | |
H8D | DB00353 | Methylergometrine | Methylergometrine is an ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery. | |
H8G | DB00589 | Lisuride | An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at... | |
H8J | DB00247 | Methysergide | Methysergide is an ergot alkaloid used for the prophylaxis of migraine and cluster headaches. | |
H98 | DB01274 | Arformoterol | Arformoterol is a beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. | |
HAE | DB00551 | Acetohydroxamic acid | Acetohydroxamic acid is a synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract. | |
HCY | DB00741 | Hydrocortisone | Hydrocortisone is a glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. | |
HCZ | DB00999 | Hydrochlorothiazide | Hydrochlorothiazide is a thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. | |
HDZ | DB09152 | Nitrogen | Nitrogen is a cryogenic agent used to treat various benign and malignant skin lesions. | |
HFG | DB04866 | Halofuginone | Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis... | |
HFT | DB00499 | Flutamide | Flutamide is an antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma. | |
HFZ | DB00774 | Hydroflumethiazide | Hydroflumethiazide is a thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. | |
HLT | DB01159 | Halothane | Halothane is a general inhalation anesthetic used for the induction and maintenance of general anesthesia. | |
HLZ | DB01275 | Hydralazine | Hydralazine is an antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia . | |
HQE | DB09526 | Hydroquinone | Hydroquinone is a topical brightening agent used for the treatment of skin disorders associated with hyperpigmentation including melasma, post-inflammatory hyperpigmentation, sunspots, and freckles. | |
HQI | DB11145 | Oxyquinoline | Oxyquinoline is a medication used in combination with other medications to restore vaginal pH. | |
HSM | DB05381 | Histamine | Histamine is an ingredient of topical drugs for the relief of joint pain or muscle aches and pains. | |
HSY | DB09419 | Xylose | Xylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional group. Xylose is a sugar isolated from wood. D-Xylose is a sugar widely... | |
HUP | DB04864 | Huperzine a | Huperzine A, is a naturally occurring sesquiterpene alkaloid found in the extracts of the firmoss Huperzia serrata. The botanical has been used in China for centuries for the treatment of... | |
HXA | DB03756 | Doconexent | Doconexent is an omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. | |
HY0 | DB11520 | Hygromycin b | Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. | |
HYO | DB00424 | Hyoscyamine | Hyoscyamine is an anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis. | |
I7A | DB01144 | Diclofenamide | Diclofenamide is a carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. | |
IBP | DB09213 | Dexibuprofen | Dexibuprofen is a pharmacologically active enantiomer of racemic ibuprofen (NSAID) used to treat pain and inflammation. | |
ICD | DB08942 | Isoxicam | Isoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States. | |
ICF | DB00753 | Isoflurane | Isoflurane is an inhaled general anesthetic used in surgery. | |
ID2 | DB00249 | Idoxuridine | Idoxuridine is a pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. | |
ID8 | DB00784 | Mefenamic acid | Mefenamic acid is an NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. | |
IDB | DB04711 | Iodipamide | Iodipamide is a contrast agent used in cholangiography and cholecystography. | |
IL2 | DB01088 | Iloprost | Iloprost is a synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH). | |
IM4 | DB11421 | Imidacloprid | Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and... | |
IMN | DB00328 | Indomethacin | Indomethacin is a nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. | |
INS | DB13178 | Inositol | Inositol is an ingredient found in a variety of nutritional products. | |
IRE | DB00317 | Gefitinib | Gefitinib is a tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria. | |
ISZ | DB00951 | Isoniazid | Isoniazid is an antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. | |
IU5 | DB01586 | Ursodeoxycholic acid | Ursodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients. | |
IVM | DB00602 | Ivermectin | Ivermectin is an anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. | |
IXX | DB00458 | Imipramine | Imipramine is a tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. | |
IZP | DB01050 | Ibuprofen | Ibuprofen is an NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. | |
J01 | DB00766 | Clavulanic acid | Clavulanic acid is a beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics. | |
J3Z | DB00655 | Estrone | Estrone is an estrogen used to treat perimenopausal and postmenopausal symptoms. | |
JEV | DB00980 | Ramelteon | Ramelteon is a melatonin receptor agonist used to treat insomnia. | |
JMS | DB00939 | Meclofenamic acid | Meclofenamic acid is an NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis. | |
JN3 | DB06777 | Chenodeoxycholic acid | Chenodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis. | |
JZ3 | DB11359 | Guaiacol | Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin.... | |
K4D | DB01195 | Flecainide | Flecainide is a class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT). | |
K5Y | DB00938 | Salmeterol | Salmeterol is a long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. | |
K86 | DB00559 | Bosentan | Bosentan is a dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. | |
KAN | DB01172 | Kanamycin | Kanamycin is an aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. | |
KKK | DB01026 | Ketoconazole | Ketoconazole is a broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. | |
KLQ | DB11799 | Bictegravir | Bictegravir is an integrase inhibitor used to treat HIV infections. | |
KTR | DB00465 | Ketorolac | Ketorolac is an NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches. | |
KXN | DB14086 | Cianidanol | An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms. | |
L89 | DB11640 | Amifampridine | Amifampridine is a voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome. | |
L8P | DB00369 | Cidofovir | Cidofovir is an antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS. | |
L9P | DB12026 | Voxilaprevir | Voxilaprevir is a nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. | |
LBH | DB06603 | Panobinostat | Panobinostat is a non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents. | |
LBM | DB11581 | Venetoclax | Venetoclax is a BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia. | |
LCR | DB06282 | Levocetirizine | Levocetirizine is an H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria. | |
LDP | DB00988 | Dopamine | Dopamine is a catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. | |
LEI | DB00859 | Penicillamine | Penicillamine is a chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis. | |
LEV | DB09078 | Lenvatinib | Lenvatinib is a receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. | |
LF7 | DB04876 | Vildagliptin | Vildagliptin is a once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus. | |
LLT | DB01265 | Telbivudine | Telbivudine is a thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST). | |
LOC | DB01394 | Colchicine | Colchicine is an alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF). | |
LPR | DB00722 | Lisinopril | Lisinopril is an ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. | |
LQQ | DB09073 | Palbociclib | Palbociclib is an endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer. | |
LQZ | DB00281 | Lidocaine | Lidocaine is a local anesthetic used in a wide variety of superficial and invasive procedures. | |
LSD | DB11423 | Lasalocid | Lasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of Streptomyces lasaliensis. | |
LSN | DB00678 | Losartan | Losartan is an angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke. | |
LUR | DB01283 | Lumiracoxib | Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in... | |
LZU | DB00679 | Thioridazine | Thioridazine is a phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder. | |
M0E | DB11377 | Bambermycins | Bambermycins are antibiotic complexes which are retrieved from the organism, Streptomyces bambergiensis. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics... | |
M4Y | DB13063 | Parthenolide | Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis. | |
MC9 | DB02300 | Calcipotriol | Calcipotriol is a topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis. | |
MF8 | DB00331 | Metformin | Metformin is a biguanide drug used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus and used off-label for insulin resistance in polycystic ovary syndrome (PCOS). | |
MI1 | DB08895 | Tofacitinib | Tofacitinib is a Janus kinase (JAK) inhibitor used to treat rheumatoid and psoriatic arthritis, and ulcerative colitis. It is not recommended to be combined with biologic therapies or potent immunosuppressants like cyclosporine or azathioprine. | |
MIG | DB00491 | Miglitol | Miglitol is an oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates. | |
MIL | DB00235 | Milrinone | Milrinone is a PDE-III inhibitor with inotropic, lusitropic, and vasodilatory properties used for the short-term treatment of acute decompensated heart failure. | |
MIX | DB01204 | Mitoxantrone | Mitoxantrone is a chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis. | |
MIY | DB01017 | Minocycline | Minocycline is a tetracycline analog used to treat a wide variety of infections in the body. | |
MK1 | DB00224 | Indinavir | Indinavir is a protease inhibitor used to treat HIV infection. | |
MMZ | DB00763 | Methimazole | Methimazole is a thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism. | |
MOA | DB01024 | Mycophenolic acid | Mycophenolic acid is an immunosuppressant used to prevent organ transplant rejections. | |
MOF | DB14512 | Mometasone furoate | Mometasone furoate is a corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus. | |
MOI | DB00295 | Morphine | Morphine is an opioid agonist used for the relief of moderate to severe acute and chronic pain. | |
MPB | DB14212 | Methylparaben | Methylparaben is used in allergenic testing. | |
MRC | DB00410 | Mupirocin | Mupirocin is an antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes. | |
MRV | DB04835 | Maraviroc | Maraviroc is a CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. | |
MTK | DB00471 | Montelukast | Montelukast is a leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. | |
MV2 | DB09357 | Dexpanthenol | Dexpanthenol is an alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN). | |
MXD | DB00350 | Minoxidil | Minoxidil is an antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage. | |
MXM | DB00814 | Meloxicam | Meloxicam is an NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. | |
MYT | DB01011 | Metyrapone | Metyrapone is a steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function. | |
MZM | DB00703 | Methazolamide | Methazolamide is a carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. | |
N6W | DB00564 | Carbamazepine | Carbamazepine is an anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia. | |
NBO | DB00461 | Nabumetone | Nabumetone is an NSAID used to treat osteoarthritis and rheumatoid arthritis. | |
NBV | DB00419 | Miglustat | Miglustat is a glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement. | |
NCT | DB00184 | Nicotine | Nicotine is a stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. | |
NDR | DB00717 | Norethisterone | Norethisterone is a synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis. | |
NFF | DB00607 | Nafcillin | Nafcillin is a penicillin derivative antibiotic used to treat susceptible staphylococcal infections. | |
NFZ | DB00336 | Nitrofural | Nitrofural is a topical antibacterial for the prevention and treatment of bacterial infections of the skin. | |
NH3 | DB11118 | Ammonia | Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium... | |
NHY | DB01005 | Hydroxyurea | Hydroxyurea is an antimetabolite used to treat sickle cell anemia crisis. | |
NIL | DB04868 | Nilotinib | Nilotinib is a kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib. | |
NIM | DB04743 | Nimesulide | Nimesulide is a cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea. | |
NMM | DB11815 | Tilarginine | Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow. | |
NMY | DB00452 | Framycetin | Framycetin is an aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus. | |
NOG | DB00367 | Levonorgestrel | Levonorgestrel is a progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives. | |
NOV | DB01051 | Novobiocin | Novobiocin is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds,... | |
NPS | DB00788 | Naproxen | Naproxen is an NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain. | |
NRK | DB11951 | Lemborexant | Lemborexant is a dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia. | |
NTI | DB00507 | Nitazoxanide | Nitazoxanide is a thiazolide anti-infective used to treat infections by protozoa, helminths, anaerobic bacteria, microaerophilic bacteria, and viruses. | |
NVP | DB00238 | Nevirapine | Nevirapine is a non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. | |
O31 | DB13879 | Glecaprevir | Glecaprevir is a Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. | |
O6P | DB06211 | Doripenem | Doripenem is an antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections. | |
OAQ | DB01096 | Oxamniquine | An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms... | |
OBN | DB01092 | Ouabain | A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell... | |
OHB | DB08797 | Salicylamide | Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.... | |
OIN | DB00572 | Atropine | Atropine is a muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. | |
OLM | DB00275 | Olmesartan | Olmesartan is an angiotensin receptor blocker (ARB) used in the treatment of hypertension. | |
OPB | DB03585 | Oxyphenbutazone | Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain. | |
OTC | DB00595 | Oxytetracycline | Oxytetracycline is a tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. | |
OXC | DB03209 | Oteracil | Oteracil is a chemotherapy agent used in combination with tegafur, cisplatin and gimeracil to treat advanced gastric cancer. | |
P06 | DB08912 | Dabrafenib | Dabrafenib is a kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. | |
P0T | DB09061 | Cannabidiol | Cannabidiol is an active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. | |
P1Z | DB00812 | Phenylbutazone | Phenylbutazone is an NSAID used to treat backache and ankylosing spondylitis. | |
P2E | DB00917 | Dinoprostone | Dinoprostone is a prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. | |
P2Z | DB00420 | Promazine | Promazine is a phenothiazine used to manage schizophrenia. | |
P31 | DB12978 | Pexidartinib | Pexidartinib is an antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. | |
P77 | DB00433 | Prochlorperazine | Prochlorperazine is a phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. | |
PAB | DB02362 | Aminobenzoic acid | Aminobenzoic acid is a drug used to reduce the progression of penile deviation in Peyronie's Disease in adults. | |
PAC | DB09269 | Phenylacetic acid | Phenylacetic acid is an agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle. | |
PAR | DB01421 | Paromomycin | Paromomycin is an aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma. | |
PD9 | DB00494 | Entacapone | Entacapone is a selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson's disease. | |
PDN | DB00635 | Prednisone | Prednisone is a corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases. | |
PE2 | DB00299 | Penciclovir | Penciclovir is a topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis. | |
PEM | DB01393 | Bezafibrate | Bezafibrate is a lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. | |
PFN | DB00573 | Fenoprofen | Fenoprofen is an anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis. | |
PL3 | DB09494 | Cetyl alcohol | Cetyl alcohol, also known as 1-hexadecanol or n-hexadecyl alcohol, is a 16-C fatty alcohol with the chemical formula CH3(CH2)15OH. It can be produced from the reduction of palmitic acid. Cetyl... | |
PLO | DB02789 | Pregnenolone | A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. | |
PM6 | DB01033 | Mercaptopurine | Mercaptopurine is an antineoplastic agent used to treat acute lymphocytic leukemia. | |
PNN | DB01053 | Benzylpenicillin | Benzylpenicillin is a penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. | |
PNT | DB00738 | Pentamidine | Pentamidine is an antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV. | |
PNV | DB00417 | Phenoxymethylpenicillin | Phenoxymethylpenicillin is a penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues. | |
PNX | DB00806 | Pentoxifylline | Pentoxifylline is a methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs. | |
POD | DB01179 | Podofilox | Podofilox is a topical agent used for the treatment of external genital warts and perianal warts. | |
PPF | DB00529 | Foscarnet | Foscarnet is an antiviral used to treat CMV, HIV, and HSV infections. | |
PQN | DB01022 | Phylloquinone | Vitamin K1 is a fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses. | |
PRL | DB01123 | Proflavine | Proflavine is a topical antiseptic agent used in wound dressings to prevent infections. | |
PS9 | DB09353 | Octasulfur | Sulfur is an ingredient of various cosmetic preparations for its keratolytic, antifungal, and antibacterial properties. | |
PX9 | DB09345 | Pramocaine | Pramocaine is a local anesthetic and antipruritic agent found in various topical preparations. | |
PXB | DB08439 | Parecoxib | Parecoxib is a selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain. | |
PZA | DB00339 | Pyrazinamide | Pyrazinamide is an antituberculosis agent used as a component of tuberculosis (TB) treatment. | |
PZE | DB00592 | Piperazine | Piperazine is a medication used to treat roundworm and pinworm. | |
PZI | DB09210 | Piracetam | Piracetam is a nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer. | |
QA1 | DB01406 | Danazol | Danazol is a synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts. | |
QDN | DB00908 | Quinidine | Quinidine is a medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. | |
QEL | DB08954 | Ifenprodil | N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer... | |
QI9 | DB00468 | Quinine | Quinine is an alkaloid used to treat uncomplicated Plasmodium falciparum malaria. | |
QKM | DB11633 | Isavuconazole | Isavuconazole is an triazole antifungal with broad spectrum of activity and good safety profile . It is approved by the FDA and EMA for the treatment of invasive aspergillosis and... | |
QMR | DB01273 | Varenicline | Varenicline is a partial agonist at nicotinic acetylcholine receptors used as an aid in smoking cessation. | |
QO7 | DB11967 | Binimetinib | Binimetinib is a medication used to treat metastatic melanoma with specific mutations. | |
QOM | DB08911 | Trametinib | Trametinib is a kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. | |
QPT | DB00958 | Carboplatin | Carboplatin is a alkylating agent used to treat advanced ovarian cancer. | |
R1Q | DB00541 | Vincristine | Vincristine is a vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. | |
RAB | DB00194 | Vidarabine | Vidarabine is an antiviral agent used to treat various viral infections. | |
RAL | DB00481 | Raloxifene | Raloxifene is a selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women. | |
RAP | DB00877 | Sirolimus | Sirolimus is an immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. | |
RAS | DB01367 | Rasagiline | Rasagiline is an irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa. | |
RAV | DB00312 | Pentobarbital | Pentobarbital is a barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. | |
RB6 | DB04918 | Ceftobiprole | Ceftobiprole is a cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria. | |
RBT | DB00615 | Rifabutin | Rifabutin is an antibiotic used to treat mycobacterium avium complex disease in patients with HIV. | |
RBV | DB00811 | Ribavirin | Ribavirin is a guanosine nucleoside used to treat some forms of Hepatitis C. | |
RCO | DB11085 | Resorcinol | Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders... | |
RCX | DB00533 | Rofecoxib | Rofecoxib is a COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks. | |
RFV | DB11753 | Rifamycin | Rifamycin is an antibacterial used to treat traveler's diarrhea. | |
RG4 | DB08877 | Ruxolitinib | Ruxolitinib is a kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment. | |
RIM | DB00478 | Rimantadine | Rimantadine is an RNA synthesis inhibitor used to prevent influenza A infection. | |
RIO | DB03615 | Ribostamycin | Ribostamycin is a broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine. | |
RIS | DB00884 | Risedronic acid | Risedronic acid is a bisphosphonate used to treat osteoporosis and Paget's disease. | |
RIT | DB00503 | Ritonavir | Ritonavir is an HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. | |
RIV | DB06228 | Rivaroxaban | Rivaroxaban is a factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations. | |
RLT | DB06817 | Raltegravir | Raltegravir is an antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals. | |
ROC | DB01232 | Saquinavir | Saquinavir is an HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. | |
ROF | DB01656 | Roflumilast | Roflumilast is a selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis. | |
RPB | DB12332 | Rucaparib | Rucaparib is an anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer. | |
RPT | DB01201 | Rifapentine | Rifapentine is an antibiotic agent used in the treatment of pulmonary tuberculosis. | |
RXM | DB01220 | Rifaximin | Rifaximin is a rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults. | |
S7W | DB09256 | Tegafur | Tegafur is an antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers. | |
S7Y | DB00969 | Alosetron | Alosetron is a 5-HT3 antagonist used to treat diarrhea-predominant IBS. | |
S87 | DB00904 | Ondansetron | Ondansetron is a serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively. | |
SAL | DB00936 | Salicylic acid | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | |
SAN | DB00259 | Sulfanilamide | Sulfanilamide is a sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. | |
SAS | DB00795 | Sulfasalazine | Sulfasalazine is an anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. | |
SC2 | DB06151 | Acetylcysteine | Acetylcysteine is a medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. | |
SCK | DB00202 | Succinylcholine | Succinylcholine is a depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. | |
SCM | DB00919 | Spectinomycin | Spectinomycin is an aminocyclitol antibiotic used to treat susceptible strains of Neisseria gonorrhoeae. | |
SFY | DB00891 | Sulfapyridine | Sulfapyridine is a sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. | |
SHH | DB02546 | Vorinostat | Vorinostat is a histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. | |
SMX | DB01326 | Cefamandole | Cefamandole is a beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections. | |
SNL | DB00421 | Spironolactone | Spironolactone is an aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, hirsutism (off-label) and hypokalemia. | |
SOR | DB01638 | Sorbitol | Sorbitol is a product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. | |
SPP | DB00705 | Delavirdine | Delavirdine is a non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. | |
SPR | DB06145 | Spiramycin | Spiramycin is a macrolide antimicrobial agent used in the treatment of various bacterial infections. | |
SRE | DB01104 | Sertraline | Sertraline is a selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. | |
SRY | DB01082 | Streptomycin | Streptomycin is an aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. | |
STI | DB00619 | Imatinib | Imatinib is a tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. | |
STR | DB00396 | Progesterone | Progesterone is a hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. | |
STZ | DB00428 | Streptozocin | Streptozocin is a nitrosourea antineoplastic agent used in the treatment of metastatic pancreatic islet cell carcinoma. | |
SUE | DB11575 | Grazoprevir | Grazoprevir is an antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections. | |
SUV | DB09034 | Suvorexant | Suvorexant is a orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance. | |
SUZ | DB00605 | Sulindac | Sulindac is an NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis. | |
SV6 | DB05521 | Telaprevir | Telaprevir is an NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. | |
T0R | DB00539 | Toremifene | Toremifene is a first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers. | |
T1C | DB00560 | Tigecycline | Tigecycline is a glycylcycline antibiotic used to treat a number of susceptible bacterial infections. | |
T22 | DB06203 | Alogliptin | Alogliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. | |
T27 | DB08864 | Rilpivirine | Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). | |
T3 | DB00279 | Liothyronine | Liothyronine is a thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism. | |
T44 | DB00451 | Levothyroxine | Levothyroxine is a synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. | |
TA1 | DB01229 | Paclitaxel | Paclitaxel is a taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. | |
TAC | DB00759 | Tetracycline | Tetracycline is an antibiotic used to treat a wide variety of susceptible infections. | |
TAZ | DB01606 | Tazobactam | Tazobactam is a beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. | |
TC9 | DB01199 | Tubocurarine | Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to... | |
TCI | DB00470 | Dronabinol | Dronabinol is a synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. | |
TCL | DB08604 | Triclosan | Triclosan is an antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew. | |
TCW | DB00323 | Tolcapone | Tolcapone is a catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease. | |
TE4 | DB09085 | Tetracaine | Tetracaine is a local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures. | |
TEI | DB04854 | Febuxostat | Febuxostat is a xanthine oxidase inhibitor used for the management of chronic hyperuricemia in adults with gout who have an inadequate response or intolerance to allopurinol. | |
TEP | DB00277 | Theophylline | Theophylline is a xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. | |
TES | DB00624 | Testosterone | Testosterone is a hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. | |
TFP | DB00831 | Trifluoperazine | Trifluoperazine is a phenothiazine used to treat depression, anxiety, and agitation. | |
THA | DB00382 | Tacrine | Tacrine is an anticholinesterase drug used for the management of Alzheimer's disease symptoms. | |
THH | DB11256 | Levomefolic acid | Levomefolic acid is a folate supplement used to prevent neural tube defects in pregnancy or folate deficiency. | |
TIC | DB00208 | Ticlopidine | Ticlopidine is a platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). | |
TIM | DB00373 | Timolol | Timolol is a non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. | |
TIQ | DB08816 | Ticagrelor | Ticagrelor is a P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death. | |
TJ7 | DB12343 | Temocillin | Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. | |
TKT | DB11699 | Tropisetron | Tropisetron is a 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting. | |
TLF | DB09216 | Tolfenamic acid | Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent. It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as... | |
TLS | DB00966 | Telmisartan | Telmisartan is an ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. | |
TLT | DB00500 | Tolmetin | Tolmetin is an NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis. | |
TMG | DB00730 | Thiabendazole | Thiabendazole is a benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections. | |
TMI | DB04794 | Bifonazole | Bifonazole is an azole antifungal drug used to treat fungal skin infections, such as dermatomycosis. | |
TMQ | DB01157 | Trimetrexate | Trimetrexate is a folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin. | |
TNG | DB00727 | Nitroglycerin | Nitroglycerin is a nitrate vasodilator used to treat or prevent angina, treat hypertension, control heart failure in myocardial infarction, and to induce hypotension intraoperatively. | |
TOP | DB00440 | Trimethoprim | Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. | |
TOR | DB00273 | Topiramate | Topiramate is an anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. | |
TOY | DB00684 | Tobramycin | Tobramycin is an aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections. | |
TP0 | DB00321 | Amitriptyline | Amitriptyline is a tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. | |
TPF | DB00196 | Fluconazole | Fluconazole is a triazole antifungal used to treat various fungal infections including candidiasis. | |
TPV | DB00932 | Tipranavir | Tipranavir is a protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. | |
TTC | DB01030 | Topotecan | Topotecan is an antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer. | |
TUA | DB00860 | Prednisolone | Prednisolone is a glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. | |
TXC | DB00577 | Valaciclovir | Valaciclovir is an guanine nucleoside antiviral used to treat herpes exacerbations. | |
TXL | DB01248 | Docetaxel | Docetaxel is a taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. | |
TYL | DB00316 | Acetaminophen | Acetaminophen is an analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. | |
TZN | DB01162 | Terazosin | Terazosin is an alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension. | |
UAS | DB00498 | Phenindione | An indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects.... | |
UQA | DB01174 | Phenobarbital | Phenobarbital is a long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. | |
URF | DB00544 | Fluorouracil | Fluorouracil is a pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment. | |
V2H | DB06410 | Doxercalciferol | Doxercalciferol is a synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis. | |
V6A | DB11942 | Selinexor | Selinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound. It is currently approved for the treatment of multiple myeloma, a cancer which forms from antibody-producing plasma cells.[L7117,L7120] This... | |
V8D | DB00292 | Etomidate | Etomidate is a short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures. | |
VDN | DB00862 | Vardenafil | Vardenafil is a phosphodiesterase 5 inhibitor used to treat erectile dysfunction. | |
VGH | DB08865 | Crizotinib | Crizotinib is a receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive. | |
VIA | DB00203 | Sildenafil | Sildenafil is a phosphodiesterase inhibitor used for the treatment of erectile dysfunction. | |
VIS | DB08828 | Vismodegib | Vismodegib is a hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. | |
VLB | DB00570 | Vinblastine | Vinblastine is a vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. | |
VOR | DB00582 | Voriconazole | Voriconazole is a triazole compound used to treat fungal infections. | |
VPX | DB09030 | Vorapaxar | Vorapaxar is a platelet aggregation inhibitor used to reduce thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or peripheral arterial disease (PAD). | |
VX7 | DB08820 | Ivacaftor | Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication. | |
W1P | DB12243 | Edaravone | Edaravone is a free radical scavenger used to delay the progression of ALS. | |
WJZ | DB06823 | Tiopronin | Tiopronin is a thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria. | |
WPP | DB00319 | Piperacillin | Piperacillin is a penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam susceptible, β-lactamase generating strains of several bacteria. | |
X0T | DB00651 | Dyphylline | Dyphylline is a theophylline derivative used to treat asthma, bronchospasm, and COPD. | |
X2N | DB01263 | Posaconazole | Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. | |
X8M | DB00332 | Ipratropium | Ipratropium is an anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD). | |
X8Z | DB01197 | Captopril | Captopril is an ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. | |
XB7 | DB00637 | Astemizole | Astemizole is a second generation antihistamine used to treat allergy symptoms. | |
XIN | DB09079 | Nintedanib | Nintedanib is a triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer. | |
XPG | DB00770 | Alprostadil | Alprostadil is a medication used to treat erectile dysfunction. | |
XRA | DB00457 | Prazosin | Prazosin is an alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension. | |
XT8 | DB01607 | Ticarcillin | Ticarcillin is a beta lactam antibiotic used to treat a variety of infections in the body. | |
Y00 | DB00841 | Dobutamine | Dobutamine is a beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. | |
YMX | DB11986 | Entrectinib | Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019... | |
YMZ | DB00358 | Mefloquine | Mefloquine is an antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax. | |
YNU | DB00700 | Eplerenone | Eplerenone is an aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. | |
YQM | DB12329 | Eravacycline | Eravacycline is a tetracycline antibiotic used to treat complicated intra-abdominal infections. | |
YTZ | DB06147 | Sulfathiazole | Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination... | |
YY3 | DB09330 | Osimertinib | Osimertinib is a tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma. | |
Z80 | DB00477 | Chlorpromazine | Chlorpromazine is a phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. | |
ZD6 | DB05294 | Vandetanib | Vandetanib is an antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease. | |
ZIO | DB11442 | Oleandomycin | Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus. | |
ZIT | DB00207 | Azithromycin | Azithromycin is a macrolide antibiotic used to treat a variety of bacterial infections. | |
ZK5 | DB00687 | Fludrocortisone | Fludrocortisone is a mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome. | |
ZLD | DB00601 | Linezolid | Linezolid is an oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. | |
ZLK | DB00549 | Zafirlukast | Zafirlukast is a leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. | |
ZMR | DB00558 | Zanamivir | Zanamivir is a neuraminidase inhibitor used to treat influenza A and B. | |
ZOL | DB00399 | Zoledronic acid | Zoledronic acid is a bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors. | |
ZON | DB00909 | Zonisamide | Zonisamide is a sulfonamide anticonvulsant used to treat partial seizures. | |
ZOT | DB09225 | Zotepine | Zotepine, with the formula (2-chloro-11-(2-dimethyl-amino-ethoxy)-dibenzo thiepin, is a neuroleptic drug. It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd. It has been used as an antipsychotic in Japan, India... | |
ZPC | DB00402 | Eszopiclone | Eszopiclone is a sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. | |
Ligand ID | Drug | DrugBank ID | Indication | View |