HEADER STRUCTURAL GENOMICS, UNKNOWN FUNCTION 28-JUN-05 2CXD COMPND CONSERVED HYPOTHETICAL PROTEIN, TTHA0068; COMPND 3 CHAIN: A, B; COMPND 4 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS; SOURCE 3 ORGANISM_TAXID: 300852; SOURCE 4 STRAIN: HB8; SOURCE 5 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 6 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 7 EXPRESSION_SYSTEM_STRAIN: B834(DE3); SOURCE 8 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 9 EXPRESSION_SYSTEM_PLASMID: PET11 AUTHOR S.KISHISHITA,K.MURAYAMA,M.SHIROUZU,S.YOKOYAMA,RIKEN STRUCTURAL AUTHOR 2 GENOMICS/PROTEOMICS INITIATIVE (RSGI) HET MSE A 1 8 HET MSE A 77 8 HET MSE B 1 8 HET MSE B 77 8 mMETA 1 47.80 31.46 8.04 47.67 30.51 7.78 48.73 33.02 9.76 48.67 32.13 10.60 48.00 32.89 8.43 46.65 33.61 8.52 2 0 1000.00-999 ?-999 ?-999 ? mVAL.A 2 49.42 34.14 9.93 49.39 34.77 9.15 49.81 35.83 11.63 49.49 36.71 10.82 50.15 34.42 11.16 51.69 34.31 10.95 3 0 1000.00-999 ?-999 ?-999 ? mPRO.A 3 49.85 36.08 12.95 50.12 35.30 13.52 50.56 38.46 13.14 51.72 38.14 12.86 49.52 37.40 13.49 49.45 37.17 15.00 3 0 1000.00-999 ?-999 ?-999 ? mASP~A 4 50.13 39.72 13.13 49.16 39.82 13.32 51.47 41.27 14.26 50.81 42.11 14.88 51.04 40.83 12.87 50.31 41.97 12.17 2 0 1000.00-999 ?-999 ?-999 ? mTRP~A 5 52.55 40.69 14.77 53.00 40.04 14.17 53.23 42.52 16.34 53.09 42.99 17.46 53.01 41.03 16.11 54.28 40.24 16.44 3 0 1000.00-999 ?-999 ?-999 ? mGLU~A 6 53.57 43.26 15.29 53.67 42.76 14.42 52.43 45.33 15.84 52.38 46.24 16.66 53.76 44.69 15.45 54.30 45.32 14.16 2 0 1000.00-999 ?-999 ?-999 ? mGLU~A 7 51.35 44.83 15.26 51.52 44.09 14.60 49.65 44.94 17.00 49.18 45.75 17.79 50.02 45.34 15.57 48.97 44.77 14.60 2 0 1000.00-999 ?-999 ?-999 ? mVAL~A 8 49.88 43.67 17.32 50.27 43.12 16.58 50.39 43.84 19.73 49.86 44.23 20.77 49.57 43.15 18.65 49.83 41.62 18.72 3 0 1000.00-999 ?-999 ?-999 ? mLEU~A 9 51.69 44.00 19.49 52.01 43.63 18.61 52.11 46.10 20.70 52.21 46.61 21.82 52.56 44.66 20.46 54.01 44.61 19.99 3 0 1000.00-999 ?-999 ?-999 ? mGLY~A 10 51.60 46.74 19.65 51.59 46.22 18.80 49.91 48.18 20.70 49.72 49.15 21.43 51.12 48.11 19.78-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mLEU~A 11 49.06 47.15 20.65 49.31 46.44 20.00 48.30 46.76 22.93 47.81 47.35 23.89 47.88 47.10 21.50 46.89 46.05 20.98 3 0 1000.00-999 ?-999 ?-999 ? mTRP~A 12 49.22 45.79 23.05 49.52 45.41 22.17 50.35 46.49 25.13 50.04 46.68 26.32 49.73 45.35 24.34 50.75 44.23 24.12 3 0 1000.00-999 ?-999 ?-999 ? mARG~A 13 51.23 47.26 24.48 51.37 46.99 23.53 50.91 49.44 25.59 51.10 50.06 26.64 51.90 48.38 25.12 52.91 49.03 24.16 2 0 1000.00-999 ?-999 ?-999 ? mALA~A 14 49.85 49.64 24.81 49.83 49.06 23.99 47.90 50.11 26.24 47.06 50.86 26.75 48.83 50.62 25.15 48.03 50.98 23.91 2 0 1000.00-999 ?-999 ?-999 ? mGLY.A 15 48.04 48.84 26.60 48.75 48.33 26.11 45.82 47.84 27.13 44.90 47.65 27.92 47.19 48.26 27.63-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mARG~A 16 45.66 47.71 25.82 46.48 47.91 25.28 44.34 45.78 25.22 44.41 45.16 24.16 44.38 47.31 25.26 44.20 47.88 23.85 2 0 1000.00-999 ?-999 ?-999 ? mTYR~A 17 44.20 45.19 26.41 44.11 45.83 27.17 43.04 43.01 25.90 43.20 41.89 25.42 44.20 43.74 26.55 44.33 43.37 28.03 3 0 1000.00-999 ?-999 ?-999 ? mTYR~A 18 41.86 43.63 25.88 41.83 44.53 26.32 40.98 42.87 23.75 40.67 41.85 23.13 40.72 42.99 25.24 39.42 43.77 25.46 3 0 1000.00-999 ?-999 ?-999 ? mGLU~A 19 41.56 43.92 23.16 41.77 44.68 23.78 42.94 42.93 21.36 42.89 42.34 20.28 41.85 43.93 21.74 42.22 45.35 21.28 2 0 1000.00-999 ?-999 ?-999 ? mVAL~A 20 43.91 42.73 22.24 43.85 43.29 23.07 44.27 40.40 21.86 44.56 39.61 20.97 44.96 41.76 21.98 46.00 41.72 23.13 3 0 1000.00-999 ?-999 ?-999 ? mHIS~A 21 43.33 40.16 22.77 43.19 40.90 23.44 41.82 38.72 21.47 41.90 37.66 20.84 42.58 38.91 22.78 41.61 38.90 23.96 3 0 1000.00-999 ?-999 ?-999 ? mGLU~A 22 41.08 39.74 21.06 41.12 40.54 21.67 41.11 39.35 18.60 40.69 38.57 17.75 40.29 39.69 19.83 39.58 41.03 19.61 2 0 1000.00-999 ?-999 ?-999 ? mVAL~A 23 42.30 39.94 18.51 42.53 40.55 19.27 43.75 38.28 17.37 43.77 37.61 16.34 43.18 39.69 17.37 44.36 40.69 17.36 3 0 1000.00-999 ?-999 ?-999 ? mLEU~A 24 44.20 37.82 18.53 44.08 38.43 19.31 43.90 35.27 18.65 44.28 34.21 18.17 44.82 36.50 18.61 45.77 36.46 19.82 3 0 1000.00-999 ?-999 ?-999 ? mGLU~A 25 42.69 35.41 19.20 42.47 36.33 19.51 41.60 33.43 18.04 41.65 32.20 18.09 41.81 34.25 19.32 40.44 34.67 19.87 2 0 1000.00-999 ?-999 ?-999 ? mPRO~A 26 41.36 34.08 16.90 41.33 35.08 16.98 42.40 32.52 15.29 42.29 31.38 14.82 41.17 33.35 15.64 40.91 34.46 14.63 3 0 1000.00-999 ?-999 ?-999 ? mTYR~A 27 43.58 33.09 15.53 43.54 34.01 15.91 44.99 31.20 16.17 45.36 30.10 15.75 44.83 32.38 15.23 46.02 33.33 15.36 3 0 1000.00-999 ?-999 ?-999 ? mTRP~A 28 44.73 31.42 17.46 44.45 32.36 17.68 43.95 29.16 18.10 44.38 28.01 18.17 44.84 30.35 18.45 44.47 30.88 19.83 3 0 1000.00-999 ?-999 ?-999 ? mLEU~A 29 42.70 29.44 17.75 42.49 30.41 17.74 42.21 27.50 16.27 42.00 26.29 16.30 41.74 28.40 17.41 40.39 29.03 17.04 3 0 1000.00-999 ?-999 ?-999 ? mLYS~A 30 42.86 28.09 15.28 42.97 29.08 15.39 44.77 26.81 14.32 45.25 26.01 13.50 43.35 27.32 14.14 43.27 28.17 12.86 2 0 1000.00-999 ?-999 ?-999 ? mALA~A 31 45.45 27.23 15.38 44.94 27.85 15.98 46.97 25.40 16.21 46.01 24.83 16.74 46.83 26.81 15.63 47.53 27.81 16.54 2 0 1000.00-999 ?-999 ?-999 ? mTHR~A 32 48.18 24.87 16.11 48.85 25.45 15.66 49.88 23.53 17.24 50.68 24.44 16.99 48.48 23.54 16.63 48.40 22.47 15.52 2 0 1000.00-999 ?-999 ?-999 ? mGLY~A 33 50.17 22.50 18.03 49.43 21.85 18.17 51.99 23.56 19.43 51.25 24.17 20.20 51.49 22.37 18.64-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mGLU~A 34 53.27 23.90 19.24 53.75 23.33 18.57 53.29 26.36 19.62 53.24 27.23 20.47 53.89 25.00 19.95 55.40 25.04 19.69 2 0 1000.00-999 ?-999 ?-999 ? mGLU~A 35 52.87 26.54 18.37 53.00 25.76 17.76 50.97 28.04 18.73 50.65 29.18 19.09 52.26 27.81 17.96 51.99 27.81 16.45 2 0 1000.00-999 ?-999 ?-999 ? mARG~A 36 50.22 26.98 18.97 50.58 26.12 18.60 49.27 27.43 21.17 48.59 28.26 21.78 48.97 27.08 19.72 48.19 25.77 19.66 2 0 1000.00-999 ?-999 ?-999 ? mARG~A 37 50.31 26.80 21.73 50.77 26.15 21.12 51.17 28.51 23.25 50.88 29.16 24.25 50.70 27.06 23.11 51.84 26.12 23.53 2 0 1000.00-999 ?-999 ?-999 ? mLEU~A 38 51.89 29.00 22.25 52.05 28.36 21.50 51.21 31.35 22.28 51.15 32.26 23.11 52.38 30.37 22.27 53.25 30.67 21.05 3 0 1000.00-999 ?-999 ?-999 ? mLEU~A 39 50.31 31.18 21.32 50.50 30.41 20.71 48.28 32.05 22.45 47.86 33.11 22.91 49.15 32.05 21.20 48.33 31.64 19.97 3 0 1000.00-999 ?-999 ?-999 ? mGLN~A 40 48.00 30.87 22.99 48.39 30.09 22.51 47.89 31.41 25.39 47.26 32.08 26.19 47.19 30.75 24.20 46.90 29.28 24.51 2 0 1000.00-999 ?-999 ?-999 ? mGLY~A 41 49.21 31.22 25.48 49.60 30.64 24.76 49.88 33.33 26.57 49.69 33.94 27.61 49.98 31.81 26.56-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mVAL~A 42 50.01 33.94 25.40 50.16 33.33 24.62 48.51 35.86 25.68 48.34 36.86 26.38 49.92 35.40 25.30 50.25 35.87 23.87 3 0 1000.00-999 ?-999 ?-999 ? mILE~A 43 47.51 35.12 25.20 47.80 34.35 24.64 45.86 35.35 27.00 45.18 36.22 27.56 46.12 35.42 25.50 45.18 34.43 24.75 3 0 1000.00-999 ?-999 ?-999 ? mLEU~A 44 46.41 34.33 27.66 46.94 33.70 27.08 46.92 35.28 29.89 46.41 35.70 30.93 46.24 34.16 29.10 46.78 32.79 29.53 3 0 1000.00-999 ?-999 ?-999 ? mLEU~A 45 48.06 35.76 29.41 48.39 35.33 28.57 47.89 38.13 29.99 47.74 38.88 30.95 48.74 36.86 30.10 50.12 37.12 29.50 3 0 1000.00-999 ?-999 ?-999 ? mALA~A 46 47.34 38.37 28.80 47.55 37.69 28.09 45.30 39.48 29.54 44.91 40.48 30.14 46.50 39.55 28.59 46.03 39.62 27.15 2 0 1000.00-999 ?-999 ?-999 ? mALA~A 47 44.74 38.28 29.68 45.18 37.56 29.14 43.93 38.29 32.02 43.13 38.85 32.77 43.59 38.05 30.55 43.07 36.62 30.36 2 0 1000.00-999 ?-999 ?-999 ? mALA~A 48 45.12 37.86 32.44 45.66 37.41 31.73 45.74 39.52 34.12 45.35 39.99 35.18 45.56 38.03 33.81 46.88 37.29 34.04 2 0 1000.00-999 ?-999 ?-999 ? mLEU~A 49 46.32 40.25 33.17 46.59 39.74 32.35 45.24 42.46 33.33 45.10 43.44 34.06 46.55 41.68 33.33 47.48 42.19 32.22 3 0 1000.00-999 ?-999 ?-999 ? mHIS~A 50 44.30 42.03 32.50 44.55 41.24 31.95 42.28 42.48 33.77 41.62 43.39 34.27 43.00 42.69 32.44 42.14 42.11 31.32 3 0 1000.00-999 ?-999 ?-999 ? mGLN~A 51 42.41 41.28 34.33 42.97 40.63 33.81 42.38 41.78 36.76 41.67 42.24 37.66 41.78 40.98 35.62 41.86 39.49 35.92 2 0 1000.00-999 ?-999 ?-999 ? mARG~A 52 43.70 41.96 36.72 44.16 41.53 35.95 43.89 44.18 37.69 43.66 44.82 38.72 44.38 42.73 37.76 45.90 42.68 37.56 2 0 1000.00-999 ?-999 ?-999 ? mARG~A 53 43.70 44.69 36.48 43.92 44.07 35.72 41.86 46.23 36.99 41.59 47.28 37.57 43.22 46.05 36.31 43.09 46.40 34.83 2 0 1000.00-999 ?-999 ?-999 ? mLEU~A 54 41.03 45.20 36.93 41.38 44.41 36.44 39.75 44.95 39.04 38.71 44.88 39.70 39.70 45.25 37.54 38.77 44.24 36.86 3 0 1000.00-999 ?-999 ?-999 ? mGLY.A 55 40.96 44.77 39.56 41.72 44.85 38.92 40.73 43.06 41.34 40.39 42.77 42.49 41.12 44.48 40.98-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mARG.A 56 40.79 42.16 40.36 41.09 42.52 39.48 41.63 39.83 40.42 42.63 40.20 39.80 40.43 40.76 40.58 39.31 40.35 39.62 2 0 1000.00-999 ?-999 ?-999 ? mPRO.A 57 41.55 38.62 40.99 40.68 38.45 41.46 43.02 37.24 39.49 42.17 36.90 38.67 42.62 37.62 40.91 42.04 36.44 41.68 3 0 1000.00-999 ?-999 ?-999 ? mGLY~A 58 44.32 37.31 39.21 44.91 37.60 39.96 45.95 35.96 37.90 46.40 35.50 36.84 44.81 36.97 37.88-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mLEU~A 59 46.41 35.60 39.09 45.94 36.03 39.86 47.21 33.26 38.69 48.12 32.50 38.39 47.51 34.65 39.23 47.94 34.57 40.70 3 0 1000.00-999 ?-999 ?-999 ? mARG~A 60 45.93 32.94 38.56 45.28 33.65 38.84 45.76 31.61 36.53 46.21 30.60 35.97 45.53 31.63 38.04 44.05 31.37 38.37 2 0 1000.00-999 ?-999 ?-999 ? mASN~A 61 45.44 32.72 35.86 45.06 33.45 36.43 47.13 32.89 34.13 47.58 32.41 33.08 45.64 32.83 34.42 44.96 34.09 33.88 2 0 1000.00-999 ?-999 ?-999 ? mLEU~A 62 47.89 33.48 35.05 47.37 33.82 35.84 50.03 32.25 34.95 50.88 31.96 34.10 49.34 33.61 34.91 49.92 34.48 36.03 3 0 1000.00-999 ?-999 ?-999 ? mARG~A 63 49.68 31.43 35.93 48.99 31.78 36.56 49.97 29.28 34.80 50.83 28.57 34.28 50.30 30.11 36.04 49.81 29.40 37.31 2 0 1000.00-999 ?-999 ?-999 ? mLYS~A 64 48.74 29.40 34.33 48.15 30.01 34.85 49.17 29.18 31.96 49.65 28.40 31.13 48.32 28.68 33.13 46.84 28.94 32.88 2 0 1000.00-999 ?-999 ?-999 ? mALA~A 65 49.35 30.50 31.89 48.89 31.02 32.61 51.58 30.56 30.87 52.17 30.22 29.84 50.15 31.10 30.82 50.16 32.63 30.97 2 0 1000.00-999 ?-999 ?-999 ? mGLU~A 66 52.14 30.49 32.08 51.55 30.81 32.82 53.65 28.55 31.84 54.67 28.17 31.27 53.50 30.00 32.28 53.90 30.13 33.75 2 0 1000.00-999 ?-999 ?-999 ? mALA~A 67 52.63 27.73 32.09 51.86 28.15 32.56 52.65 26.21 30.17 53.28 25.33 29.58 52.69 26.33 31.69 51.53 25.55 32.31 2 0 1000.00-999 ?-999 ?-999 ? mARG~A 68 51.90 27.10 29.52 51.43 27.76 30.11 53.11 27.55 27.42 53.53 27.00 26.40 51.80 27.09 28.07 50.67 28.01 27.60 2 0 1000.00-999 ?-999 ?-999 ? mLEU~A 69 53.74 28.56 28.03 53.29 28.88 28.86 56.24 28.36 27.92 57.27 28.44 27.25 54.98 29.12 27.50 55.10 30.58 27.92 3 0 1000.00-999 ?-999 ?-999 ? mGLU~A 70 56.14 27.61 29.01 55.22 27.64 29.42 57.94 25.93 28.54 57.32 25.02 27.98 57.25 26.84 29.56 56.76 26.00 30.74 2 0 1000.00-999 ?-999 ?-999 ? mGLY.A 71 59.23 26.17 28.31 59.61 26.95 28.81 59.92 25.69 25.91 60.55 25.03 25.09 59.98 25.35 27.39-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mLEU.A 72 59.16 26.73 25.56 58.69 27.19 26.31 60.31 27.84 23.68 60.98 28.53 24.45 59.06 27.12 24.16 57.87 28.06 23.93 3 0 1000.00-999 ?-999 ?-999 ? mPRO.A 73 60.65 27.69 22.40 60.08 27.09 21.84 61.45 29.88 21.91 60.25 30.22 21.87 61.84 28.40 21.94 62.08 27.82 20.55 3 0 1000.00-999 ?-999 ?-999 ? mCYH.A 74 62.44 30.76 21.96 63.35 30.36 22.03 63.32 32.85 21.16 64.49 32.66 21.50 62.18 32.19 21.92 62.10 32.76 23.34 2 0 1000.00-999 ?-999 ?-999 ? mPRO.A 75 63.00 33.63 20.12 63.80 34.02 19.67 60.88 32.73 19.04 61.45 31.67 18.81 61.63 33.91 19.65 61.83 35.05 18.66 3 0 1000.00-999 ?-999 ?-999 ? mLEU.A 76 59.59 32.94 18.80 59.27 33.85 19.06 57.69 32.72 17.42 57.08 33.64 17.96 58.73 31.93 18.20 58.05 31.09 19.29 3 0 1000.00-999 ?-999 ?-999 ? mMETA 77 57.50 32.37 16.15 58.05 31.59 15.85 56.98 34.53 15.17 56.15 35.40 14.88 56.56 33.08 15.29 55.13 33.01 15.86 2 0 1000.00-999 ?-999 ?-999 ? mGLY.A 78 58.26 34.80 15.39 58.82 34.00 15.62 58.46 37.00 16.52 58.58 38.23 16.49 58.77 36.15 15.30-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mLEU.A 79 58.06 36.36 17.61 58.01 35.36 17.52 58.63 36.74 20.01 58.91 35.57 20.27 57.72 37.08 18.83 56.27 36.80 19.23 3 0 1000.00-999 ?-999 ?-999 ? mASP~A 80 59.10 37.77 20.70 58.84 38.67 20.34 58.90 37.55 23.03 58.57 38.58 23.61 59.92 37.58 21.89 60.89 38.74 22.09 2 0 1000.00-999 ?-999 ?-999 ? mTRP~A 81 58.40 36.35 23.31 58.77 35.60 22.77 57.93 36.31 25.76 57.19 36.66 26.67 57.39 36.20 24.34 56.66 34.86 24.18 3 0 1000.00-999 ?-999 ?-999 ? mARG~A 82 59.21 36.00 25.95 59.71 35.73 25.12 59.73 37.48 27.85 59.52 37.66 29.05 59.81 36.08 27.28 61.27 35.63 27.25 2 0 1000.00-999 ?-999 ?-999 ? mSER~A 83 59.91 38.48 27.00 60.10 38.20 26.06 58.43 40.18 27.92 58.25 40.90 28.90 59.84 39.86 27.44 60.25 40.81 26.32 2 0 1000.00-999 ?-999 ?-999 ? mLEU~A 84 57.43 39.64 27.22 57.72 39.09 26.44 55.74 39.18 28.94 55.04 39.74 29.80 56.03 39.86 27.60 55.10 39.30 26.52 3 0 1000.00-999 ?-999 ?-999 ? mLEU~A 85 56.25 37.97 29.12 56.78 37.62 28.35 56.69 38.00 31.53 56.10 38.15 32.60 56.03 37.25 30.37 56.61 35.84 30.28 3 0 1000.00-999 ?-999 ?-999 ? mGLN~A 86 57.91 38.47 31.31 58.27 38.29 30.39 57.92 40.48 32.74 57.83 40.79 33.93 58.65 39.21 32.33 60.07 39.53 31.83 2 0 1000.00-999 ?-999 ?-999 ? mGLU~A 87 57.39 41.20 31.76 57.55 40.83 30.84 55.37 42.11 32.79 55.03 42.78 33.77 56.65 42.44 32.02 56.27 43.14 30.70 2 0 1000.00-999 ?-999 ?-999 ? mALA~A 88 54.67 41.07 32.36 55.06 40.61 31.56 53.70 40.35 34.50 52.93 40.78 35.37 53.44 40.65 33.02 52.86 39.43 32.33 2 0 1000.00-999 ?-999 ?-999 ? mARG~A 89 54.77 39.62 34.78 55.30 39.33 33.99 55.34 40.53 37.00 54.91 40.59 38.16 55.11 39.28 36.16 56.37 38.41 36.22 2 0 1000.00-999 ?-999 ?-999 ? mARG~A 90 56.01 41.53 36.43 56.32 41.35 35.50 54.95 43.48 37.47 54.71 43.89 38.61 56.26 42.77 37.16 57.17 43.71 36.35 2 0 1000.00-999 ?-999 ?-999 ? mARG~A 91 54.09 43.61 36.46 54.40 43.22 35.60 51.85 43.53 37.59 51.03 44.15 38.26 52.79 44.27 36.64 52.09 44.44 35.29 2 0 1000.00-999 ?-999 ?-999 ? mLEU~A 92 51.97 42.21 37.63 52.69 41.84 37.03 51.70 41.20 39.88 51.07 40.61 40.74 51.12 41.39 38.48 50.86 40.03 37.82 3 0 1000.00-999 ?-999 ?-999 ? mGLY~A 93 52.91 41.71 40.08 53.32 42.17 39.29 53.97 40.17 41.69 54.09 39.79 42.86 53.56 41.59 41.38-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mALA.A 94 54.19 39.38 40.64 54.06 39.83 39.76 56.03 37.81 40.31 56.27 36.89 39.50 54.59 37.99 40.79 53.65 37.09 39.98 2 0 1000.00-999 ?-999 ?-999 ? mMETB 1 40.18 43.37 55.21 40.40 44.33 55.01 41.12 41.13 55.73 42.06 41.17 54.93 39.86 41.95 55.50 39.04 41.35 54.35 2 0 1000.00-999 ?-999 ?-999 ? mVAL.B 2 41.14 40.40 56.84 40.31 40.47 57.40 42.00 38.11 56.86 40.89 37.62 57.05 42.28 39.56 57.20 42.60 39.66 58.71 3 0 1000.00-999 ?-999 ?-999 ? mPRO.B 3 43.01 37.40 56.34 43.86 37.91 56.23 42.65 35.10 57.20 43.05 35.46 58.31 42.85 35.99 55.97 44.17 35.67 55.26 3 0 1000.00-999 ?-999 ?-999 ? mASP~B 4 42.02 33.95 57.00 41.71 33.80 56.06 43.11 32.18 58.12 43.22 31.15 57.45 41.82 33.00 58.08 40.64 32.07 57.78 2 0 1000.00-999 ?-999 ?-999 ? mTRP~B 5 44.08 32.65 58.88 43.86 33.48 59.39 45.29 30.51 59.32 46.11 29.72 58.86 45.37 31.98 58.96 46.30 32.72 59.92 3 0 1000.00-999 ?-999 ?-999 ? mGLU~B 6 44.31 30.13 60.13 43.70 30.86 60.45 43.99 27.94 59.21 44.60 26.89 59.01 44.18 28.73 60.50 42.98 28.51 61.42 2 0 1000.00-999 ?-999 ?-999 ? mGLU~B 7 43.16 28.48 58.33 42.74 29.34 58.63 44.17 27.86 56.19 44.62 26.81 55.74 42.89 27.86 57.04 41.77 28.63 56.33 2 0 1000.00-999 ?-999 ?-999 ? mVAL~B 8 44.75 29.04 55.99 44.27 29.81 56.43 47.12 28.32 55.74 47.77 27.61 54.97 45.97 29.18 55.21 46.44 30.66 55.16 3 0 1000.00-999 ?-999 ?-999 ? mLEU~B 9 47.37 28.37 57.04 46.77 28.98 57.57 48.23 26.08 57.38 49.18 25.32 57.25 48.45 27.58 57.62 48.59 27.86 59.12 3 0 1000.00-999 ?-999 ?-999 ? mGLY~B 10 46.97 25.67 57.33 46.28 26.38 57.47 47.14 23.87 55.69 47.75 22.81 55.51 46.66 24.27 57.08-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mLEU~B 11 46.86 24.72 54.70 46.35 25.53 54.98 48.82 24.44 53.28 49.42 23.57 52.67 47.29 24.45 53.33 46.73 25.51 52.38 3 0 1000.00-999 ?-999 ?-999 ? mTRP~B 12 49.43 25.42 53.93 48.81 26.06 54.39 51.57 24.31 54.57 52.54 23.80 54.00 50.88 25.54 53.97 51.28 26.80 54.75 3 0 1000.00-999 ?-999 ?-999 ? mARG~B 13 51.09 23.84 55.71 50.31 24.36 56.07 51.52 21.42 55.53 52.34 20.50 55.60 51.67 22.67 56.38 51.01 22.42 57.72 2 0 1000.00-999 ?-999 ?-999 ? mALA~B 14 50.46 21.38 54.73 49.88 22.19 54.77 51.00 20.28 52.59 50.95 19.36 51.79 50.19 20.24 53.88 48.70 20.18 53.55 2 0 1000.00-999 ?-999 ?-999 ? mGLY.B 15 51.76 21.36 52.41 51.72 22.04 53.14 51.78 21.94 49.99 52.25 21.81 48.87 52.57 21.50 51.21-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mARG~B 16 50.57 22.46 50.21 50.31 22.50 51.17 50.03 24.40 48.84 49.19 25.27 49.05 49.72 22.93 49.11 48.25 22.75 49.48 2 0 1000.00-999 ?-999 ?-999 ? mTYR~B 17 51.24 24.66 48.38 51.80 23.84 48.22 50.93 26.79 47.07 50.62 27.97 47.26 51.70 26.01 48.13 53.19 25.96 47.80 3 0 1000.00-999 ?-999 ?-999 ? mTYR~B 18 50.63 26.16 45.94 50.96 25.21 45.88 48.54 27.29 45.49 48.08 28.40 45.24 49.87 26.83 44.89 49.59 25.87 43.74 3 0 1000.00-999 ?-999 ?-999 ? mGLU~B 19 47.95 26.41 46.30 48.45 25.56 46.41 46.76 27.89 47.90 45.88 28.75 47.91 46.68 26.69 46.95 46.22 25.44 47.71 2 0 1000.00-999 ?-999 ?-999 ? mVAL~B 20 47.83 27.96 48.70 48.47 27.20 48.61 48.04 30.37 48.79 47.40 31.37 49.12 48.00 29.09 49.62 49.32 28.96 50.42 3 0 1000.00-999 ?-999 ?-999 ? mHIS~B 21 48.79 30.32 47.70 49.23 29.43 47.57 47.62 31.90 46.24 47.33 33.09 46.19 48.97 31.44 46.80 49.92 31.02 45.67 3 0 1000.00-999 ?-999 ?-999 ? mGLU~B 22 46.78 30.93 45.86 47.14 30.01 45.98 44.49 31.83 46.34 43.78 32.79 46.04 45.47 31.23 45.31 44.87 29.97 44.68 2 0 1000.00-999 ?-999 ?-999 ? mVAL~B 23 44.46 31.27 47.54 45.09 30.50 47.66 43.90 33.19 49.04 43.01 33.97 49.36 43.57 31.76 48.59 43.60 30.83 49.83 3 0 1000.00-999 ?-999 ?-999 ? mLEU~B 24 45.19 33.53 49.07 45.81 32.82 48.76 45.52 36.03 48.56 45.45 37.17 49.00 45.61 34.86 49.53 47.05 34.78 50.05 3 0 1000.00-999 ?-999 ?-999 ? mGLU~B 25 45.50 35.76 47.26 45.52 34.79 47.02 44.37 37.90 46.53 44.65 39.10 46.51 45.45 36.85 46.28 45.35 36.30 44.84 2 0 1000.00-999 ?-999 ?-999 ? mPRO~B 26 43.12 37.47 46.76 42.98 36.48 46.74 42.34 39.39 48.17 42.05 40.58 48.11 42.04 38.45 47.00 40.83 37.56 47.28 3 0 1000.00-999 ?-999 ?-999 ? mTYR~B 27 42.92 38.85 49.24 43.10 37.87 49.17 44.36 40.65 50.11 44.33 41.80 50.57 43.25 39.66 50.42 43.69 38.76 51.57 3 0 1000.00-999 ?-999 ?-999 ? mTRP~B 28 45.35 40.20 49.34 45.24 39.25 49.05 46.02 42.24 48.13 46.38 43.38 48.41 46.47 41.05 48.96 47.49 40.23 48.16 3 0 1000.00-999 ?-999 ?-999 ? mLEU~B 29 45.23 41.97 47.10 45.02 40.99 46.98 44.01 44.15 46.95 44.06 45.29 46.51 44.72 43.02 46.22 43.78 42.42 45.17 3 0 1000.00-999 ?-999 ?-999 ? mLYS~B 30 43.35 43.84 48.07 43.41 42.87 48.34 43.38 45.47 49.99 42.88 46.37 50.66 42.62 44.85 48.82 41.29 44.28 49.33 2 0 1000.00-999 ?-999 ?-999 ? mALA~B 31 44.59 44.99 50.24 44.89 44.26 49.61 46.29 46.66 50.89 46.51 46.85 49.69 45.40 45.50 51.33 46.26 44.38 51.92 2 0 1000.00-999 ?-999 ?-999 ? mTHR~B 32 46.78 47.41 51.87 46.48 47.13 52.78 48.73 48.55 52.73 48.63 47.78 53.69 47.69 48.53 51.62 46.95 49.88 51.65 2 0 1000.00-999 ?-999 ?-999 ? mGLY~B 33 49.73 49.41 52.60 49.70 49.96 51.76 51.47 48.23 53.94 51.71 47.40 53.06 50.76 49.53 53.61-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mGLU~B 34 51.81 48.05 55.21 51.54 48.80 55.81 51.72 45.57 55.45 52.31 44.52 55.19 52.51 46.86 55.66 52.88 46.99 57.13 2 0 1000.00-999 ?-999 ?-999 ? mGLU~B 35 50.40 45.64 55.55 50.03 46.54 55.76 49.74 43.92 53.94 49.81 42.70 53.71 49.59 44.44 55.37 48.11 44.73 55.66 2 0 1000.00-999 ?-999 ?-999 ? mARG~B 36 49.78 44.83 52.99 49.71 45.78 53.30 51.30 43.82 51.39 51.44 42.84 50.67 49.93 44.45 51.59 49.78 45.67 50.68 2 0 1000.00-999 ?-999 ?-999 ? mARG~B 37 52.31 44.38 52.04 52.07 45.17 52.60 53.74 42.44 52.51 54.37 41.56 51.93 53.66 43.85 51.92 54.66 44.78 52.62 2 0 1000.00-999 ?-999 ?-999 ? mLEU~B 38 53.08 42.23 53.65 52.61 43.04 54.01 52.44 39.86 53.41 53.02 38.81 53.16 53.08 40.92 54.30 52.32 40.96 55.63 3 0 1000.00-999 ?-999 ?-999 ? mLEU~B 39 51.23 40.15 52.94 50.88 41.05 53.21 51.24 38.92 50.79 51.29 37.78 50.34 50.49 39.22 52.09 49.09 39.78 51.81 3 0 1000.00-999 ?-999 ?-999 ? mGLN~B 40 51.86 39.94 50.19 51.79 40.83 50.64 53.82 38.84 49.25 54.22 37.99 48.44 52.58 39.68 48.96 52.97 40.98 48.25 2 0 1000.00-999 ?-999 ?-999 ? mGLY~B 41 54.42 39.06 50.42 53.99 39.77 50.98 55.28 36.83 51.02 56.04 35.96 50.58 55.59 38.30 50.80-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mVAL~B 42 54.17 36.54 51.69 53.66 37.34 52.00 53.40 34.48 50.62 53.72 33.31 50.39 53.77 35.15 51.94 52.57 35.09 52.91 3 0 1000.00-999 ?-999 ?-999 ? mILE~B 43 52.74 35.23 49.75 52.52 36.15 50.09 53.61 34.37 47.62 53.65 33.32 46.97 52.36 34.74 48.43 51.56 35.81 47.65 3 0 1000.00-999 ?-999 ?-999 ? mLEU~B 44 54.62 35.23 47.67 54.46 36.04 48.23 56.61 33.76 47.50 57.27 33.04 46.75 55.86 34.98 46.94 56.76 36.22 46.98 3 0 1000.00-999 ?-999 ?-999 ? mLEU~B 45 56.51 33.53 48.81 55.97 34.20 49.32 56.48 31.11 48.92 57.13 30.12 48.59 57.17 32.37 49.41 57.10 32.43 50.94 3 0 1000.00-999 ?-999 ?-999 ? mALA~B 46 55.15 31.14 48.88 54.74 32.00 49.19 54.69 29.75 46.94 54.83 28.61 46.51 54.37 30.00 48.41 52.88 30.27 48.59 2 0 1000.00-999 ?-999 ?-999 ? mALA~B 47 54.83 30.82 46.16 54.69 31.70 46.63 56.53 30.06 44.57 56.72 29.17 43.73 55.15 30.69 44.74 55.11 32.07 44.06 2 0 1000.00-999 ?-999 ?-999 ? mALA~B 48 57.49 30.51 45.37 57.20 31.22 46.00 58.84 28.46 45.52 59.47 27.71 44.77 58.85 29.98 45.29 59.74 30.67 46.32 2 0 1000.00-999 ?-999 ?-999 ? mLEU~B 49 58.14 28.02 46.56 57.68 28.74 47.09 57.27 25.83 45.79 57.60 24.69 45.47 58.06 26.60 46.86 57.44 26.40 48.25 3 0 1000.00-999 ?-999 ?-999 ? mHIS~B 50 56.26 26.47 45.22 56.07 27.39 45.55 56.41 25.66 42.96 56.33 24.66 42.24 55.50 25.80 44.17 54.25 26.57 43.78 3 0 1000.00-999 ?-999 ?-999 ? mGLN~B 51 57.27 26.65 42.73 57.20 27.41 43.38 59.11 25.38 41.76 59.37 24.67 40.79 58.21 26.60 41.61 59.08 27.87 41.56 2 0 1000.00-999 ?-999 ?-999 ? mARG~B 52 59.58 25.13 42.98 59.31 25.78 43.68 59.66 22.68 42.94 60.22 21.70 42.43 60.44 23.98 43.22 60.97 24.00 44.66 2 0 1000.00-999 ?-999 ?-999 ? mARG~B 53 58.37 22.69 43.26 58.05 23.54 43.66 57.45 21.25 41.52 57.29 20.10 41.09 57.52 21.52 43.02 56.11 21.79 43.54 2 0 1000.00-999 ?-999 ?-999 ? mLEU~B 54 57.57 22.31 40.72 57.69 23.17 41.21 58.92 21.97 38.67 59.10 22.02 37.45 57.53 22.20 39.26 56.90 23.46 38.67 3 0 1000.00-999 ?-999 ?-999 ? mGLY.B 55 59.90 21.73 39.53 59.63 21.73 40.49 62.08 22.71 38.71 62.97 22.65 37.86 61.26 21.48 39.06-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mARG.B 56 61.80 23.83 39.37 61.05 23.75 40.03 63.09 25.62 40.43 62.54 25.36 41.49 62.54 25.06 39.12 61.64 26.09 38.43 2 0 1000.00-999 ?-999 ?-999 ? mPRO.B 57 64.20 26.39 40.37 64.53 26.50 39.43 63.99 27.75 42.52 64.11 27.55 43.73 64.88 27.00 41.52 65.90 27.92 40.86 3 0 1000.00-999 ?-999 ?-999 ? mGLY~B 58 63.12 28.61 42.01 63.12 28.68 41.01 63.00 30.43 43.67 62.45 31.07 44.57 62.24 29.38 42.88-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mLEU~B 59 64.26 30.63 43.32 64.58 30.07 42.56 64.73 33.06 43.70 64.92 33.95 44.53 65.09 31.61 44.01 66.57 31.35 43.70 3 0 1000.00-999 ?-999 ?-999 ? mARG~B 60 64.20 33.30 42.50 64.12 32.49 41.91 62.61 35.10 42.98 62.55 36.24 43.42 63.80 34.65 42.12 63.42 34.71 40.64 2 0 1000.00-999 ?-999 ?-999 ? mASN~B 61 61.67 34.18 43.21 61.84 33.30 42.78 60.92 34.71 45.49 60.40 35.61 46.14 60.51 34.49 44.03 59.47 33.37 43.94 2 0 1000.00-999 ?-999 ?-999 ? mLEU~B 62 61.84 33.89 45.98 62.17 33.20 45.34 62.93 35.39 47.58 62.70 36.03 48.60 62.31 34.01 47.36 63.35 32.93 47.68 3 0 1000.00-999 ?-999 ?-999 ? mARG~B 63 63.73 35.82 46.61 63.83 35.18 45.84 63.35 38.23 46.72 63.48 39.16 47.50 64.39 37.11 46.66 65.30 37.28 45.44 2 0 1000.00-999 ?-999 ?-999 ? mLYS~B 64 62.32 38.14 45.88 62.32 37.34 45.27 60.51 39.10 47.22 60.16 40.14 47.78 61.28 39.15 45.90 60.31 38.97 44.72 2 0 1000.00-999 ?-999 ?-999 ? mALA~B 65 60.27 37.90 47.73 60.61 37.13 47.19 60.31 38.46 50.12 59.73 39.21 50.90 59.56 37.76 48.99 59.37 36.28 49.32 2 0 1000.00-999 ?-999 ?-999 ? mGLU~B 66 61.62 38.22 50.19 61.96 37.60 49.48 62.44 40.33 51.13 62.47 41.02 52.15 62.45 38.81 51.22 63.88 38.26 51.11 2 0 1000.00-999 ?-999 ?-999 ? mALA~B 67 62.38 40.85 49.92 62.36 40.18 49.18 61.04 42.87 50.28 61.05 43.93 50.90 62.34 42.29 49.70 62.44 42.61 48.20 2 0 1000.00-999 ?-999 ?-999 ? mARG~B 68 59.94 42.16 50.10 60.06 41.31 49.60 58.49 42.50 52.13 57.81 43.31 52.75 58.65 42.63 50.61 57.51 41.88 49.91 2 0 1000.00-999 ?-999 ?-999 ? mLEU~B 69 59.10 41.48 52.72 59.64 40.90 52.10 59.94 42.04 55.03 59.67 42.28 56.20 58.96 41.25 54.15 59.12 39.76 54.45 3 0 1000.00-999 ?-999 ?-999 ? mGLU~B 70 61.06 42.44 54.46 61.15 42.21 53.49 61.57 44.38 55.98 60.93 45.26 55.41 62.08 43.16 55.22 63.22 43.61 54.31 2 0 1000.00-999 ?-999 ?-999 ? mGLY.B 71 61.88 44.41 57.28 62.38 43.61 57.61 60.08 45.49 58.66 59.66 46.43 59.34 61.49 45.53 58.11-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mLEU.B 72 59.35 44.42 58.37 59.79 43.73 57.81 58.02 43.82 60.31 58.89 43.05 60.70 57.99 44.32 58.88 57.17 43.34 58.04 3 0 1000.00-999 ?-999 ?-999 ? mPRO.B 73 57.06 44.26 61.13 56.40 44.91 60.75 56.59 42.33 62.45 55.96 41.92 61.47 57.07 43.77 62.51 56.08 44.69 63.21 3 0 1000.00-999 ?-999 ?-999 ? mCYH.B 74 56.90 41.55 63.48 57.44 41.99 64.19 56.12 39.84 64.97 56.93 40.05 65.87 56.47 40.15 63.53 57.57 39.22 63.04 2 0 1000.00-999 ?-999 ?-999 ? mPRO.B 75 54.90 39.32 65.21 54.76 39.15 66.19 53.20 40.25 63.58 53.39 41.39 64.01 53.87 39.03 64.21 52.88 38.18 65.00 3 0 1000.00-999 ?-999 ?-999 ? mLEU.B 76 52.41 39.99 62.55 52.37 39.02 62.30 50.40 40.35 61.37 50.46 39.23 60.86 51.67 41.03 61.85 52.47 41.55 60.66 3 0 1000.00-999 ?-999 ?-999 ? mMETB 77 49.25 41.01 61.55 49.36 41.91 61.95 47.79 39.14 61.97 47.01 38.26 61.61 47.97 40.42 61.16 47.93 40.10 59.65 2 0 1000.00-999 ?-999 ?-999 ? mGLY.B 78 48.53 39.04 63.08 49.13 39.82 63.25 49.25 36.68 63.43 49.17 35.59 63.99 48.46 37.87 63.94-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mLEU.B 79 50.03 36.90 62.38 50.03 37.84 62.04 52.32 35.92 62.01 52.91 36.99 61.84 50.82 35.82 61.78 50.56 35.77 60.28 3 0 1000.00-999 ?-999 ?-999 ? mASP~B 80 52.92 34.81 62.41 52.31 34.03 62.54 54.99 34.37 61.27 55.28 33.20 61.01 54.37 34.76 62.61 54.73 33.71 63.68 2 0 1000.00-999 ?-999 ?-999 ? mTRP~B 81 55.19 35.36 60.41 54.93 36.27 60.75 57.23 34.79 59.08 57.74 34.20 58.12 55.74 35.13 59.08 55.49 36.34 58.18 3 0 1000.00-999 ?-999 ?-999 ? mARG~B 82 57.94 35.18 60.13 57.41 35.68 60.83 59.58 33.39 60.11 60.48 32.94 59.41 59.36 34.89 60.24 59.90 35.35 61.60 2 0 1000.00-999 ?-999 ?-999 ? mSER~B 83 58.75 32.63 60.81 58.08 33.13 61.35 58.64 30.64 59.38 59.32 29.70 58.96 58.85 31.17 60.79 57.81 30.56 61.73 2 0 1000.00-999 ?-999 ?-999 ? mLEU~B 84 57.70 31.24 58.66 57.21 31.97 59.14 58.61 31.08 56.39 58.97 30.24 55.57 57.41 30.83 57.30 56.20 31.59 56.76 3 0 1000.00-999 ?-999 ?-999 ? mLEU~B 85 59.23 32.25 56.54 58.83 32.85 57.23 61.56 31.64 56.01 62.21 31.16 55.08 60.41 32.60 55.75 60.85 34.03 56.07 3 0 1000.00-999 ?-999 ?-999 ? mGLN~B 86 61.84 31.37 57.29 61.25 31.84 57.94 62.66 29.06 57.09 63.58 28.38 56.62 62.92 30.46 57.65 63.06 30.40 59.17 2 0 1000.00-999 ?-999 ?-999 ? mGLU~B 87 61.40 28.64 57.12 60.75 29.28 57.52 61.21 27.29 55.09 61.68 26.30 54.53 61.03 27.32 56.61 59.58 27.00 56.96 2 0 1000.00-999 ?-999 ?-999 ? mALA~B 88 60.82 28.38 54.43 60.45 29.10 55.01 62.40 28.40 52.53 62.74 27.68 51.59 60.94 28.47 52.97 60.30 29.77 52.47 2 0 1000.00-999 ?-999 ?-999 ? mARG~B 89 63.27 29.15 53.20 62.87 29.70 53.94 65.26 27.75 53.05 66.02 27.26 52.21 64.68 29.15 52.86 65.46 30.15 53.72 2 0 1000.00-999 ?-999 ?-999 ? mARG~B 90 64.89 27.10 54.15 64.27 27.62 54.74 64.92 24.75 53.39 65.72 23.95 52.92 65.36 25.76 54.44 64.88 25.31 55.83 2 0 1000.00-999 ?-999 ?-999 ? mARG~B 91 63.63 24.78 53.04 63.08 25.47 53.50 63.69 24.11 50.65 63.84 23.19 49.85 63.12 23.85 52.04 61.58 23.90 51.99 2 0 1000.00-999 ?-999 ?-999 ? mLEU~B 92 64.01 25.37 50.36 63.84 26.03 51.09 66.07 25.49 49.01 66.70 25.72 47.99 64.56 25.70 49.06 64.22 27.14 48.67 3 0 1000.00-999 ?-999 ?-999 ? mGLY.B 93 66.64 25.03 50.13 66.01 24.89 50.90 68.88 26.06 50.12 69.98 26.08 49.58 68.07 24.79 50.20-999.99-999.99-999.99 1 0 1000.00-999 ?-999 ?-999 ? mALA.B 94 68.31 27.14 50.66 67.41 26.98 51.05 69.57 28.69 52.04 70.81 28.80 52.15 68.98 28.43 50.66 67.99 29.54 50.29 2 0 1000.00-999 ?-999 ?-999 ?