Sequence Similarity : Non-homologous sequences (<30%) SEQUENCE SIMILARITY (%) 1am9A 1am9B 1h89A 1hloA 1hloB 1uiiA 1uiiB 2b9cA 2b9cB 2j5uA 2j5uB 2w6aA 2x7aA 2zxxA 2zxxB 3azdA 3azdB 3basA 3basB 3ii6A 3ii6B 3vn0A 3vn0B 4athA 4athB 4bwdA 4bwdB 4mt8A 4mt8B 4owiA 4owiB 4rfxA 4rfxB 5dolA 5dolB 5fcnA 5fcnB 5fiyA 5fiyB 5fv8A 5fv8E 5hzpA 5hzpC 5to5A 5to5B 6aozA 6aozB 1am9A 100 99 7 35 36 3 7 7 19 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1am9B 20 100 14 34 35 9 9 11 7 0 0 7 0 12 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1h89A 2 9 100 4 9 7 7 8 0 0 0 7 12 14 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1hloA 18 8 2 100 90 4 7 18 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1hloB 13 35 9 90 100 6 6 4 2 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1uiiA 15 9 13 4 6 100 92 3 0 0 0 16 12 10 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1uiiB 5 9 15 4 7 92 100 3 0 0 0 18 12 10 84 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2b9cA 0 0 9 0 0 9 0 100 83 0 0 0 6 0 0 0 0 13 0 0 46 0 9 23 0 0 0 23 0 0 0 28 0 7 0 7 0 0 10 0 0 7 5 47 21 6 6 2b9cB 19 7 0 2 0 0 0 57 100 0 0 7 3 13 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2j5uA 0 0 0 0 0 0 0 0 0 100 98 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2j5uB 0 0 0 0 0 0 0 0 0 98 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2w6aA 11 7 9 0 7 16 18 5 7 0 0 100 21 11 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2x7aA 14 10 8 5 4 12 12 5 3 0 0 21 100 10 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2zxxA 5 5 15 8 6 11 11 18 1 0 0 11 8 100 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2zxxB 15 10 13 5 9 90 84 14 13 0 0 16 12 9 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3azdA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 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0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6aozB 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 FOLD SIMILARITY (Z-SCORE) 1am9A 1am9B 1h89A 1hloA 1hloB 1uiiA 1uiiB 2b9cA 2b9cB 2j5uA 2j5uB 2w6aA 2x7aA 2zxxA 2zxxB 3azdA 3azdB 3basA 3basB 3ii6A 3ii6B 3vn0A 3vn0B 4athA 4athB 4bwdA 4bwdB 4mt8A 4mt8B 4owiA 4owiB 4rfxA 4rfxB 5dolA 5dolB 5fcnA 5fcnB 5fiyA 5fiyB 5fv8A 5fv8E 5hzpA 5hzpC 5to5A 5to5B 6aozA 6aozB 1am9A 10.9 9.3 3.1 7.3 7.3 4.1 4.1 3.8 3.6 0 0 3.6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1am9B 5.9 10.8 4.2 7.4 7.5 4.1 4.1 4 3.7 0 0 3.6 0 3.5 3.3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1h89A 2.1 4.2 7.6 3.1 3.9 6.3 6.1 4.1 5.3 0 0 5.3 6.1 5.3 5.3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1hloA 5 4.8 3.6 11.1 9 3.8 4 3.6 0 0 0 3.5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1hloB 5.1 7.5 3.9 9 11 3.6 3.4 3.1 3.3 0 0 3.3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1uiiA 4.3 4.1 6.2 3.8 3.6 7.6 6.5 4 5.2 0 0 5.6 6.2 5.7 5.5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1uiiB 3.3 4.1 6 3.6 3.8 6.5 7.4 3.8 5 0 0 5.4 5.9 5.5 5.3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2b9cA 0 0 3 0 0 3.2 0 9.2 4.9 0 0 0 2.4 0 0 0 0 2.2 0 0 3.8 0 3.2 2.3 0 0 0 2.6 0 0 0 4 0 3.2 0 3.4 0 0 4.7 0 0 3 3.4 4.3 1.8 4.1 3.4 2b9cB 3.1 3.4 5.2 3.1 3.7 5.1 5 7.4 9.4 0 0 3.3 3.7 3.7 3.8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2j5uA 0 0 0 0 0 0 0 0 0 36.4 30.3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2j5uB 0 0 0 0 0 0 0 0 0 30.3 35.3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2w6aA 2.7 3.7 5.3 3.2 3.3 5.6 5.4 3.2 3.3 0 0 7.7 5.5 4.6 4.7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2x7aA 3.8 4.2 6 3.7 3.9 6.2 5.9 3.8 3.7 0 0 5.5 7.4 5.3 5.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2zxxA 3.4 3.1 5.3 2.5 3.2 5.5 5.4 5.7 5.1 0 0 4.6 5.3 7.9 5.4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2zxxB 3.6 3.6 5.2 3.5 3.3 5.5 5.3 5.5 5.2 0 0 4.7 5.2 5.3 8.6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3azdA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3azdB 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3basA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3basB 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3ii6A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3ii6B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3vn0A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3vn0B 0 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