DRUG BINDING INTERFACES MAPPED TO '5xdx'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
Filter list by:
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
5XDX_A_CUA603 5xdx CU

DB09130
(Copper)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 1
PF00115
(COX1)
3 HIS A 240
HIS A 290
HIS A 291
 CU A 603
5XDX_B_CHDB302 5xdx CHD

DB02659
(Cholic
Acid)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 1;
CYTOCHROME C OXIDASE
SUBUNIT 2;
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL
None
PF00115
(COX1)
PF00116
(COX2)
PF02790
(COX2_TM)
11 ARG T  14
ARG T  17
PHE T  21
GLY T  22
GLN B  59
GLU B  62
THR B  63
THR B  66
MET A 271
GLY A 272
TRP A 275
CHD B 302
5XDX_C_CHDC301 5xdx CHD

DB02659
(Cholic
Acid)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 1;
CYTOCHROME C OXIDASE
SUBUNIT 3
None
PF00115
(COX1)
PF00510
(COX3)
9 TRP C  99
HIS C 103
LEU P 127
HIS A 233
TRP A 288
MET A 297
ASP A 300
THR A 301
TYR A 304
CHD C 301
5XDX_C_CHDC308 5xdx CHD

DB02659
(Cholic
Acid)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 3;
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART
PF00510
(COX3)
PF02238
(COX7a)
5 PHE J   1
ARG C 156
LEU C 160
PHE C 164
LEU C 223
CHD C 308
5XDX_J_CHDJ101 5xdx CHD

DB02659
(Cholic
Acid)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 1;
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART
PF00115
(COX1)
PF02238
(COX7a)
7 ILE A   3
LEU A   7
TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
CHD J 101
5XDX_N_CUN603 5xdx CU

DB09130
(Copper)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 1
None 3 HIS N 240
HIS N 290
HIS N 291
 CU N 603
5XDX_O_CHDO301 5xdx CHD

DB02659
(Cholic
Acid)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 1;
CYTOCHROME C OXIDASE
SUBUNIT 2;
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL
None
PF02046
(COX6A)
10 ARG G  14
ARG G  17
PHE G  21
GLY G  22
GLU O  62
THR O  63
THR O  66
MET N 271
GLY N 272
TRP N 275
CHD O 301
5XDX_P_CHDP301 5xdx CHD

DB02659
(Cholic
Acid)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 1;
CYTOCHROME C OXIDASE
SUBUNIT 3
None
PF00510
(COX3)
8 TRP P  99
HIS P 103
LEU C 127
HIS N 233
TRP N 288
ASP N 300
THR N 301
TYR N 304
CHD P 301
5XDX_P_CHDP306 5xdx CHD

DB02659
(Cholic
Acid)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 3;
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART
None 5 PHE W   1
ARG P 156
LEU P 160
PHE P 164
LEU P 223
CHD P 306
5XDX_W_CHDW101 5xdx CHD

DB02659
(Cholic
Acid)
Bos taurus CYTOCHROME C OXIDASE
SUBUNIT 1;
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART
None 8 ILE N   3
LEU N   7
PHE N   8
TYR W  32
ARG W  33
MET W  36
THR W  37
LEU W  40
CHD W 101