DRUG BINDING INTERFACES MAPPED TO '5x66'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
5X66_A_MTXA402	5x66	MTX DB00563 (Methotrexate)	Homo sapiens	THYMIDYLATE SYNTHASE	PF00303 (Thymidylat_synt) no annotation	12	ARG A 78 PHE A 80 ILE A 108 ASP B 119 ASP A 218 LEU A 221 GLY A 222 PHE A 225 ASN A 226 TYR A 258 MET A 311 ALA A 312	MTX A 402
5X66_B_MTXB402	5x66	MTX DB00563 (Methotrexate)	Homo sapiens	THYMIDYLATE SYNTHASE	no annotation	11	PHE B 80 ILE B 108 ASP B 218 LEU B 221 GLY B 222 PHE B 225 ASN B 226 TYR B 258 THR B 306 MET B 311 ALA B 312	MTX B 402
5X66_C_MTXC402	5x66	MTX DB00563 (Methotrexate)	Homo sapiens	THYMIDYLATE SYNTHASE	no annotation	9	ILE C 108 ASP C 218 LEU C 221 GLY C 222 PHE C 225 ASN C 226 TYR C 258 MET C 311 ALA C 312	MTX C 402
5X66_D_MTXD402	5x66	MTX DB00563 (Methotrexate)	Homo sapiens	THYMIDYLATE SYNTHASE	no annotation	10	ARG D 78 PHE D 80 ILE D 108 ASP D 218 GLY D 222 PHE D 225 ASN D 226 TYR D 258 MET D 311 ALA D 312	MTX D 402
5X66_E_MTXE402	5x66	MTX DB00563 (Methotrexate)	Homo sapiens	THYMIDYLATE SYNTHASE	no annotation	11	PHE E 80 LYS E 107 ILE E 108 ASP E 218 LEU E 221 GLY E 222 PHE E 225 ASN E 226 TYR E 258 MET E 311 ALA E 312	MTX E 402
5X66_F_MTXF402	5x66	MTX DB00563 (Methotrexate)	Homo sapiens	THYMIDYLATE SYNTHASE	no annotation	12	LYS F 77 PHE F 80 ILE F 108 ASP F 218 LEU F 221 GLY F 222 PHE F 225 TYR F 258 THR F 306 MET F 311 ALA F 312 VAL F 313	MTX F 402

[["5X66_A_MTXA402","5x66","MTX","DB00563(Methotrexate)","Homo sapiens","THYMIDYLATE SYNTHASE","PF00303(Thymidylat_synt);no annotation",12,"ARG A  78;PHE A  80;ILE A 108;ASP B 119;ASP A 218;LEU A 221;GLY A 222;PHE A 225;ASN A 226;TYR A 258;MET A 311;ALA A 312","MTX A 402\r"],["5X66_B_MTXB402","5x66","MTX","DB00563(Methotrexate)","Homo sapiens","THYMIDYLATE SYNTHASE","no annotation",11,"PHE B  80;ILE B 108;ASP B 218;LEU B 221;GLY B 222;PHE B 225;ASN B 226;TYR B 258;THR B 306;MET B 311;ALA B 312","MTX B 402\r"],["5X66_C_MTXC402","5x66","MTX","DB00563(Methotrexate)","Homo sapiens","THYMIDYLATE SYNTHASE","no annotation",9,"ILE C 108;ASP C 218;LEU C 221;GLY C 222;PHE C 225;ASN C 226;TYR C 258;MET C 311;ALA C 312","MTX C 402\r"],["5X66_D_MTXD402","5x66","MTX","DB00563(Methotrexate)","Homo sapiens","THYMIDYLATE SYNTHASE","no annotation",10,"ARG D  78;PHE D  80;ILE D 108;ASP D 218;GLY D 222;PHE D 225;ASN D 226;TYR D 258;MET D 311;ALA D 312","MTX D 402\r"],["5X66_E_MTXE402","5x66","MTX","DB00563(Methotrexate)","Homo sapiens","THYMIDYLATE SYNTHASE","no annotation",11,"PHE E  80;LYS E 107;ILE E 108;ASP E 218;LEU E 221;GLY E 222;PHE E 225;ASN E 226;TYR E 258;MET E 311;ALA E 312","MTX E 402\r"],["5X66_F_MTXF402","5x66","MTX","DB00563(Methotrexate)","Homo sapiens","THYMIDYLATE SYNTHASE","no annotation",12,"LYS F  77;PHE F  80;ILE F 108;ASP F 218;LEU F 221;GLY F 222;PHE F 225;TYR F 258;THR F 306;MET F 311;ALA F 312;VAL F 313","MTX F 402\r"]]