DRUG BINDING INTERFACES MAPPED TO '5lf3'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
5LF3_B_BO2B305 5lf3 BO2

DB00188
(Bortezomib)
Homo sapiens PROTEASOME SUBUNIT
BETA TYPE-6;
PROTEASOME SUBUNIT
BETA TYPE-7
PF00227
(Proteasome)
PF10584
(Proteasome_A_N)
no annotation
14 THR b   1
THR b  20
THR b  21
THR b  22
LYS b  33
ARG b  45
SER b  46
GLY b  47
ALA b  49
THR b  52
MET b  95
TYR V 114
SER V 118
SER b 169
BO2 b 305
5LF3_H_BO2H306 5lf3 BO2

DB00188
(Bortezomib)
Homo sapiens PROTEASOME SUBUNIT
BETA TYPE-3;
PROTEASOME SUBUNIT
BETA TYPE-7
PF00227
(Proteasome)
PF12465
(Pr_beta_C)
10 THR H   1
ALA H  20
THR H  21
GLU H  22
CYS H  31
ALA H  46
GLY H  47
ALA H  49
THR H  52
ASP I 124
BO2 H 306
5LF3_K_BO2K305 5lf3 BO2

DB00188
(Bortezomib)
Homo sapiens PROTEASOME SUBUNIT
BETA TYPE-1;
PROTEASOME SUBUNIT
BETA TYPE-5
PF00227
(Proteasome)
11 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
MET K  45
GLY K  47
GLY K  48
ALA K  49
ASP L 125
TYR K 169
BO2 K 305
5LF3_N_BO2N304 5lf3 BO2

DB00188
(Bortezomib)
Homo sapiens PROTEASOME SUBUNIT
BETA TYPE-6;
PROTEASOME SUBUNIT
BETA TYPE-7
PF00227
(Proteasome)
PF12465
(Pr_beta_C)
14 THR N   1
THR N  20
THR N  21
THR N  22
LYS N  33
ARG N  45
SER N  46
GLY N  47
ALA N  49
THR N  52
MET N  95
TYR H 114
SER H 118
SER N 169
BO2 N 304
5LF3_V_BO2V303 5lf3 BO2

DB00188
(Bortezomib)
Homo sapiens PROTEASOME SUBUNIT
BETA TYPE-3;
PROTEASOME SUBUNIT
BETA TYPE-7
no annotation 10 THR V   1
ALA V  20
THR V  21
GLU V  22
LYS V  33
ALA V  46
GLY V  47
ALA V  49
THR V  52
ASP W 124
BO2 V 303
5LF3_Y_BO2Y305 5lf3 BO2

DB00188
(Bortezomib)
Homo sapiens PROTEASOME SUBUNIT
BETA TYPE-1;
PROTEASOME SUBUNIT
BETA TYPE-5
no annotation 11 THR Y   1
ALA Y  20
THR Y  21
ALA Y  22
LYS Y  33
MET Y  45
GLY Y  47
GLY Y  48
ALA Y  49
ASP Z 125
TYR Y 169
BO2 Y 305