DRUG BINDING INTERFACES MAPPED TO '5l5z'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
5L5Z_B_BO2B201 5l5z BO2

DB00188
(Bortezomib)
Saccharomyces
cerevisiae
PROTEASOME SUBUNIT
BETA TYPE-1;
PROTEASOME SUBUNIT
BETA TYPE-2
PF00227
(Proteasome)
PF10584
(Proteasome_A_N)
no annotation
12 THR b   1
THR b  20
THR b  21
THR b  22
LYS b  33
ARG b  45
SER b  46
GLY b  47
ALA b  49
THR b  52
HIS V 114
SER V 118
BO2 b 201
5L5Z_H_BO2H301 5l5z BO2

DB00188
(Bortezomib)
Saccharomyces
cerevisiae
PROTEASOME SUBUNIT
BETA TYPE-2;
PROTEASOME SUBUNIT
BETA TYPE-3
PF00227
(Proteasome)
PF12465
(Pr_beta_C)
12 THR H   1
SER H  20
THR H  21
GLN H  22
CYS H  31
LYS H  33
ALA H  46
GLY H  47
ALA H  49
THR H  52
ASP I 124
CYS I 128
BO2 H 301
5L5Z_K_BO2K301 5l5z BO2

DB00188
(Bortezomib)
Homo sapiens;
Saccharomyces
cerevisiae
PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5;
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6
PF00227
(Proteasome)
9 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
LYS K  33
GLY K  47
ALA K  49
ASP L 126
BO2 K 301
5L5Z_N_BO2N201 5l5z BO2

DB00188
(Bortezomib)
Saccharomyces
cerevisiae
PROTEASOME SUBUNIT
BETA TYPE-1;
PROTEASOME SUBUNIT
BETA TYPE-2
PF00227
(Proteasome)
PF12465
(Pr_beta_C)
12 THR N   1
THR N  20
THR N  21
THR N  22
LYS N  33
ARG N  45
SER N  46
GLY N  47
ALA N  49
THR N  52
HIS H 114
SER H 118
BO2 N 201
5L5Z_V_BO2V301 5l5z BO2

DB00188
(Bortezomib)
Saccharomyces
cerevisiae
PROTEASOME SUBUNIT
BETA TYPE-2;
PROTEASOME SUBUNIT
BETA TYPE-3
no annotation 12 THR V   1
SER V  20
THR V  21
GLN V  22
CYS V  31
LYS V  33
ALA V  46
GLY V  47
ALA V  49
THR V  52
ASP W 124
CYS W 128
BO2 V 301
5L5Z_Y_BO2Y301 5l5z BO2

DB00188
(Bortezomib)
Homo sapiens;
Saccharomyces
cerevisiae
PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5;
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6
no annotation 9 THR Y   1
ALA Y  20
THR Y  21
ALA Y  22
ALA Y  27
LYS Y  33
GLY Y  47
ALA Y  49
ASP Z 126
BO2 Y 301