DRUG BINDING INTERFACES MAPPED TO '5hie'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
5HIE_A_P06A801 | 5hie | P06 DB08912(Dabrafenib) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE B-RAF | PF07714(Pkinase_Tyr) | 19 | ILE A 463GLY A 464GLY A 466PHE A 468VAL A 471ALA A 481LYS A 483PHE A 498LEU A 505LEU A 514PHE A 516ILE A 527THR A 529TRP A 531CYS A 532PHE A 583GLY A 593ASP A 594PHE A 595 | P06 A 801 |
5HIE_B_P06B801 | 5hie | P06 DB08912(Dabrafenib) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE B-RAF | no annotation | 19 | ILE B 463GLY B 464GLY B 466PHE B 468VAL B 471ALA B 481LYS B 483PHE B 498LEU B 505LEU B 514PHE B 516ILE B 527THR B 529TRP B 531CYS B 532PHE B 583GLY B 593ASP B 594PHE B 595 | P06 B 801 |
5HIE_C_P06C801 | 5hie | P06 DB08912(Dabrafenib) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE B-RAF | no annotation | 19 | ILE C 463GLY C 464GLY C 466PHE C 468VAL C 471ALA C 481LYS C 483VAL C 504LEU C 514PHE C 516ILE C 527THR C 529TRP C 531CYS C 532ASN C 580PHE C 583GLY C 593ASP C 594PHE C 595 | P06 C 801 |
5HIE_D_P06D801 | 5hie | P06 DB08912(Dabrafenib) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE B-RAF | no annotation | 20 | ILE D 463GLY D 464GLY D 466PHE D 468VAL D 471ALA D 481LYS D 483PHE D 498VAL D 504LEU D 514PHE D 516ILE D 527THR D 529TRP D 531CYS D 532ASN D 580PHE D 583GLY D 593ASP D 594PHE D 595 | P06 D 801 |