DRUG BINDING INTERFACES MAPPED TO '4ypa'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
4YPA_A_SAMA3004 4ypa SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L
PF00856
(SET)
12 LYS A2150
GLY A2151
TRP A2152
ASP A2192
TYR A2194
ASN A2217
HIS A2218
TYR A2255
GLN A2266
CYS A2268
LYS A2269
ILE A2279
SAM A3004
4YPA_B_SAMB2304 4ypa SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L
None 13 LYS B2150
GLY B2151
TRP B2152
ASP B2192
HIS B2193
TYR B2194
ASN B2217
HIS B2218
TYR B2255
GLN B2266
CYS B2268
LYS B2269
ILE B2279
SAM B2304
4YPA_C_SAMC2304 4ypa SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L
None 13 LYS C2150
GLY C2151
TRP C2152
ASP C2192
HIS C2193
TYR C2194
ASN C2217
HIS C2218
TYR C2255
GLN C2266
CYS C2268
LYS C2269
ILE C2279
SAM C2304
4YPA_D_SAMD2304 4ypa SAM

DB00118
(S-
Adenosylmethionine)
Homo sapiens HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L
None 13 LYS D2150
GLY D2151
TRP D2152
ASP D2192
HIS D2193
TYR D2194
ASN D2217
HIS D2218
TYR D2255
GLN D2266
CYS D2268
LYS D2269
ILE D2279
SAM D2304