DRUG BINDING INTERFACES MAPPED TO '4xv2'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 4XV2_A_P06A801 | 4xv2 | P06 DB08912(Dabrafenib) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE B-RAF | PF07714(Pkinase_Tyr) | 16 | GLY A 466PHE A 468VAL A 471ALA A 481LYS A 483LEU A 505LEU A 514PHE A 516ILE A 527THR A 529TRP A 531CYS A 532PHE A 583GLY A 593ASP A 594PHE A 595 | P06 A 801 |
| 4XV2_B_P06B801 | 4xv2 | P06 DB08912(Dabrafenib) | Homo sapiens | SERINE/THREONINE-PROTEIN KINASE B-RAF | no annotation | 16 | GLY B 466PHE B 468VAL B 471ALA B 481LYS B 483LEU B 505LEU B 514PHE B 516ILE B 527THR B 529TRP B 531CYS B 532PHE B 583GLY B 593ASP B 594PHE B 595 | P06 B 801 |