DRUG BINDING INTERFACES MAPPED TO '4v04'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 4V04_A_0LIA1772 | 4v04 | 0LI DB08901(Ponatinib) | Homo sapiens | FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B | PF07714(Pkinase_Tyr) | 20 | VAL A 492ALA A 512LYS A 514GLU A 531MET A 534MET A 535ILE A 545VAL A 561TYR A 563ALA A 564LEU A 614CYS A 619HIS A 621ARG A 622LEU A 630ILE A 639ALA A 640ASP A 641PHE A 642GLY A 643 | 0LI A1772 |
| 4V04_B_0LIB1771 | 4v04 | 0LI DB08901(Ponatinib) | Homo sapiens | FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B | no annotation | 22 | LEU B 484VAL B 492ALA B 512LYS B 514GLU B 531MET B 534MET B 535ILE B 545VAL B 561TYR B 563ALA B 564LEU B 614CYS B 619HIS B 621ARG B 622LEU B 630ILE B 639ALA B 640ASP B 641PHE B 642GLY B 643LEU B 644 | 0LI B1771 |