DRUG BINDING INTERFACES MAPPED TO '4ky8'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
4KY8_A_MTXA603
4ky8
MTX
DB00563(Methotrexate)
Cryptosporidiumhominis
BIFUNCTIONALTHYMIDYLATESYNTHASE-DIHYDROFOLATE REDUCTASE
PF00186(DHFR_1)PF00303(Thymidylat_synt)
12
VAL A 9ALA A 11LEU A 25ASP A 32LEU A 33LYS A 34SER A 37SER A 61ILE A 62LEU A 67ARG A 70THR A 134
MTX A 603
4KY8_B_MTXB603
4ky8
MTX
DB00563(Methotrexate)
Cryptosporidiumhominis
BIFUNCTIONALTHYMIDYLATESYNTHASE-DIHYDROFOLATE REDUCTASE
no annotation
12
VAL B 9ALA B 11LEU B 25ASP B 32LEU B 33LYS B 34SER B 37SER B 61ILE B 62LEU B 67ARG B 70THR B 134
MTX B 603
4KY8_C_MTXC603
4ky8
MTX
DB00563(Methotrexate)
Cryptosporidiumhominis
BIFUNCTIONALTHYMIDYLATESYNTHASE-DIHYDROFOLATE REDUCTASE
no annotation
12
VAL C 9ALA C 11LEU C 25ASP C 32LEU C 33LYS C 34SER C 37SER C 61ILE C 62LEU C 67ARG C 70THR C 134
MTX C 603
4KY8_D_MTXD603
4ky8
MTX
DB00563(Methotrexate)
Cryptosporidiumhominis
BIFUNCTIONALTHYMIDYLATESYNTHASE-DIHYDROFOLATE REDUCTASE
no annotation
12
VAL D 9ALA D 11LEU D 25ASP D 32LEU D 33LYS D 34SER D 37SER D 61ILE D 62LEU D 67ARG D 70THR D 134
MTX D 603
4KY8_E_MTXE603
4ky8
MTX
DB00563(Methotrexate)
Cryptosporidiumhominis
BIFUNCTIONALTHYMIDYLATESYNTHASE-DIHYDROFOLATE REDUCTASE
no annotation
12
VAL E 9ALA E 11LEU E 25ASP E 32LEU E 33LYS E 34SER E 37SER E 61ILE E 62LEU E 67ARG E 70THR E 134
MTX E 603
[["4KY8_A_MTXA603","4ky8","MTX","DB00563(Methotrexate)","Cryptosporidium hominis","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","PF00186(DHFR_1);PF00303(Thymidylat_synt)",12,"VAL A 9;ALA A 11;LEU A 25;ASP A 32;LEU A 33;LYS A 34;SER A 37;SER A 61;ILE A 62;LEU A 67;ARG A 70;THR A 134","MTX A 603\r"],["4KY8_B_MTXB603","4ky8","MTX","DB00563(Methotrexate)","Cryptosporidium hominis","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","no annotation",12,"VAL B 9;ALA B 11;LEU B 25;ASP B 32;LEU B 33;LYS B 34;SER B 37;SER B 61;ILE B 62;LEU B 67;ARG B 70;THR B 134","MTX B 603\r"],["4KY8_C_MTXC603","4ky8","MTX","DB00563(Methotrexate)","Cryptosporidium hominis","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","no annotation",12,"VAL C 9;ALA C 11;LEU C 25;ASP C 32;LEU C 33;LYS C 34;SER C 37;SER C 61;ILE C 62;LEU C 67;ARG C 70;THR C 134","MTX C 603\r"],["4KY8_D_MTXD603","4ky8","MTX","DB00563(Methotrexate)","Cryptosporidium hominis","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","no annotation",12,"VAL D 9;ALA D 11;LEU D 25;ASP D 32;LEU D 33;LYS D 34;SER D 37;SER D 61;ILE D 62;LEU D 67;ARG D 70;THR D 134","MTX D 603\r"],["4KY8_E_MTXE603","4ky8","MTX","DB00563(Methotrexate)","Cryptosporidium hominis","BIFUNCTIONAL THYMIDYLATE SYNTHASE-DIHYDROFOLATE REDUCTASE","no annotation",12,"VAL E 9;ALA E 11;LEU E 25;ASP E 32;LEU E 33;LYS E 34;SER E 37;SER E 61;ILE E 62;LEU E 67;ARG E 70;THR E 134","MTX E 603\r"]]