DRUG BINDING INTERFACES MAPPED TO '4gh8'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
4GH8_A_MTXA201 | 4gh8 | MTX DB00563(Methotrexate) | Escherichia coli | DIHYDROFOLATEREDUCTASE | PF00186(DHFR_1) | 15 | ILE A 5ALA A 7MET A 20ASP A 28LEU A 29LYS A 33SER A 50ILE A 51PRO A 52ASN A 55LEU A 58ARG A 61ILE A 98TYR A 104THR A 117 | MTX A 201 |
4GH8_B_MTXB201 | 4gh8 | MTX DB00563(Methotrexate) | Escherichia coli | DIHYDROFOLATEREDUCTASE | no annotation | 14 | ILE B 5ALA B 7MET B 20ASP B 28LEU B 29LYS B 33SER B 50ILE B 51PRO B 52ASN B 55ARG B 61ILE B 98TYR B 104THR B 117 | MTX B 201 |