DRUG BINDING INTERFACES MAPPED TO '3s3v'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
3S3V_A_TOPA187 3s3v TOP

DB00440
(Trimethoprim)
Homo sapiens DIHYDROFOLATE
REDUCTASE
PF00186
(DHFR_1)
12 ILE A   7
ALA A   9
GLU A  30
PHE A  31
PHE A  34
LYS A  35
THR A  56
ILE A  60
LEU A  67
VAL A 115
TYR A 121
THR A 136
TOP A 187
3S3V_A_TOPA193 3s3v TOP

DB00440
(Trimethoprim)
Homo sapiens DIHYDROFOLATE
REDUCTASE
PF00186
(DHFR_1)
5 ASP A  21
LEU A  22
ILE A  60
PRO A  61
PHE A  64
TOP A 193