DRUG BINDING INTERFACES MAPPED TO '3jwq'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
Filter list by:
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
3JWQ_A_VIAA901 3jwq VIA

DB00203
(Sildenafil)
Homo sapiens CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA
PF00233
(PDEase_I)
9 TYR A 612
HIS A 613
LEU A 725
VAL A 782
MET A 804
LEU A 813
GLN A 817
PHE A 820
VAL A 824
VIA A 901
3JWQ_B_VIAB901 3jwq VIA

DB00203
(Sildenafil)
Homo sapiens CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA
no annotation 11 TYR B 612
HIS B 613
ASN B 661
LEU B 725
ALA B 767
VAL B 782
THR C 795
MET B 804
LEU B 813
GLN B 817
PHE B 820
VIA B 901
3JWQ_C_VIAC901 3jwq VIA

DB00203
(Sildenafil)
Homo sapiens CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA
no annotation 7 TYR C 612
HIS C 613
MET C 804
LEU C 813
GLN C 817
PHE C 820
VAL C 824
VIA C 901
3JWQ_D_VIAD901 3jwq VIA

DB00203
(Sildenafil)
Homo sapiens CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA
PF00233
(PDEase_I)
no annotation
11 TYR D 612
HIS D 613
LEU D 725
ALA D 767
PHE D 786
ARG A 794
GLN A 798
MET D 804
LEU D 813
GLN D 817
PHE D 820
VIA D 901