DRUG BINDING INTERFACES MAPPED TO '2wek'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
2WEK_A_DIFA1373 2wek DIF

DB00586
(Diclofenac)
Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
8 ASN A  75
SER A  77
PHE A  98
MET A 124
VAL A 155
TYR A 275
PHE A 304
ASN A 306
DIF A1373
2WEK_A_DIFA1374 2wek DIF

DB00586
(Diclofenac)
Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
5 TYR A  86
MET A 124
PRO A 126
ASN A 306
LEU A 309
DIF A1374
2WEK_A_DIFA1375 2wek DIF

DB00586
(Diclofenac)
Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
3 LEU A 309
TYR A 312
GLN A 313
DIF A1375
2WEK_A_DIFA1376 2wek DIF

DB00586
(Diclofenac)
Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
8 TYR A 161
LEU A 164
LYS A 165
LEU A 192
LYS A 195
ALA A 196
HIS A 318
MET A 322
DIF A1376
2WEK_B_DIFB1373 2wek DIF

DB00586
(Diclofenac)
Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2
no annotation 8 ASN B  75
SER B  77
PHE B  98
MET B 124
VAL B 155
TYR B 275
PHE B 304
ASN B 306
DIF B1373
2WEK_B_DIFB1374 2wek DIF

DB00586
(Diclofenac)
Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2
no annotation 6 TYR B  86
MET B 124
PRO B 126
ILE B 139
ASN B 306
LEU B 309
DIF B1374
2WEK_B_DIFB1375 2wek DIF

DB00586
(Diclofenac)
Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2
no annotation 5 TYR B 161
LYS B 165
LEU B 192
LYS B 195
HIS B 318
DIF B1375
2WEK_B_DIFB1376 2wek DIF

DB00586
(Diclofenac)
Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2
no annotation 7 TYR B 224
VAL B 248
GLY B 250
ALA B 251
MET B 252
LEU B 255
SER B 273
DIF B1376