DRUG BINDING INTERFACES MAPPED TO '2w3a'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 2W3A_A_TOPA1190 | 2w3a | TOP DB00440(Trimethoprim) | Homo sapiens | DIHYDROFOLATEREDUCTASE | PF00186(DHFR_1) | 11 | ILE A 7ALA A 9GLU A 30PHE A 31PHE A 34THR A 56ILE A 60PRO A 61VAL A 115TYR A 121THR A 136 | TOP A1190 |
| 2W3A_B_TOPB1189 | 2w3a | TOP DB00440(Trimethoprim) | Homo sapiens | DIHYDROFOLATEREDUCTASE | no annotation | 10 | ILE B 7ALA B 9GLU B 30PHE B 31PHE B 34THR B 56ILE B 60LEU B 67TYR B 121THR B 136 | TOP B1189 |