DRUG BINDING INTERFACES MAPPED TO '2hyy'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
2HYY_A_STIA600 | 2hyy | STI DB00619(Imatinib) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 | PF07714(Pkinase_Tyr) | 18 | LEU A 248TYR A 253VAL A 256ALA A 269LYS A 271GLU A 286VAL A 289MET A 290ILE A 293VAL A 299ILE A 313THR A 315PHE A 317GLY A 321ARG A 362LEU A 370ALA A 380ASP A 381 | STI A 600 |
2HYY_B_STIB600 | 2hyy | STI DB00619(Imatinib) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 | no annotation | 18 | LEU B 248TYR B 253VAL B 256ALA B 269LYS B 271GLU B 286VAL B 289MET B 290ILE B 293VAL B 299ILE B 313THR B 315PHE B 317MET B 318GLY B 321LEU B 370ALA B 380ASP B 381 | STI B 600 |
2HYY_C_STIC600 | 2hyy | STI DB00619(Imatinib) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 | no annotation | 18 | LEU C 248TYR C 253VAL C 256ALA C 269LYS C 271GLU C 286VAL C 289MET C 290ILE C 293VAL C 299ILE C 313THR C 315PHE C 317MET C 318GLY C 321LEU C 370ALA C 380ASP C 381 | STI C 600 |
2HYY_D_STID600 | 2hyy | STI DB00619(Imatinib) | Homo sapiens | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 | no annotation | 16 | LEU D 248TYR D 253VAL D 256ALA D 269LYS D 271GLU D 286MET D 290ILE D 293VAL D 299ILE D 313THR D 315PHE D 317MET D 318LEU D 370ALA D 380ASP D 381 | STI D 600 |