DRUG BINDING INTERFACES MAPPED TO '2h42'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 2H42_A_VIAA901 | 2h42 | VIA DB00203(Sildenafil) | Homo sapiens | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE | PF00233(PDEase_I) | 11 | TYR A 612HIS A 613ASN A 661ALA A 767ILE A 768VAL A 782PHE A 786LEU A 804ILE A 813GLN A 817PHE A 820 | VIA A 901 |
| 2H42_B_VIAB902 | 2h42 | VIA DB00203(Sildenafil) | Homo sapiens | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE | no annotation | 12 | TYR B 612HIS B 613ASN B 661ALA B 767ILE B 768VAL B 782ALA B 783LEU B 804ILE B 813MET B 816GLN B 817PHE B 820 | VIA B 902 |
| 2H42_C_VIAC903 | 2h42 | VIA DB00203(Sildenafil) | Homo sapiens | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE | no annotation | 15 | TYR C 612ASN C 661ILE C 665LEU C 725LEU C 765ALA C 767ILE C 768VAL C 782ALA C 783PHE C 786LEU C 804ILE C 813MET C 816GLN C 817PHE C 820 | VIA C 903 |