DRUG BINDING INTERFACES MAPPED TO '1uwh'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 1UWH_A_BAXA1723 | 1uwh | BAX DB00398(Sorafenib) | Homo sapiens | B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE | PF07714(Pkinase_Tyr) | 18 | ILE A 462VAL A 470ALA A 480GLU A 500VAL A 503LEU A 504ILE A 512LEU A 513THR A 528TRP A 530CYS A 531LEU A 566ILE A 571HIS A 573PHE A 582GLY A 592ASP A 593PHE A 594 | BAX A1723 |
| 1UWH_B_BAXB1723 | 1uwh | BAX DB00398(Sorafenib) | Homo sapiens | B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE | no annotation | 18 | ILE B 462VAL B 470ALA B 480LYS B 482GLU B 500VAL B 503LEU B 504ILE B 512LEU B 513THR B 528TRP B 530CYS B 531LEU B 566ILE B 571HIS B 573PHE B 582GLY B 592ASP B 593 | BAX B1723 |