DRUG BINDING INTERFACES MAPPED TO '1nw3'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1NW3_A_ACTA600 1nw3 ACT

DB03166
(Acetic
acid) 		Homo sapiens HISTONE
METHYLTRANSFERASE
DOT1L 		PF08123
(DOT1) 		5 LEU A 158
VAL A 160
TYR A 183
ARG A 231
THR A 235
 ACT A 600
1NW3_A_SAMA500 1nw3 SAM

DB00118
(S-
Adenosylmethionine) 		Homo sapiens HISTONE
METHYLTRANSFERASE
DOT1L 		PF08123
(DOT1) 		16 TYR A 136
GLU A 138
THR A 139
ASP A 161
GLY A 163
GLN A 168
VAL A 169
GLU A 186
LYS A 187
ALA A 188
ASP A 222
PHE A 223
LEU A 224
PHE A 239
ASN A 241
PHE A 245
 SAM A 500