DRUG BINDING INTERFACES MAPPED TO 'X2N'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
2X2N_A_X2NA1480	2x2n	X2N DB01263 (Posaconazole)	Trypanosoma brucei	LANOSTEROL 14-ALPHA-DEMETHYLASE	PF00067 (p450)	14	TYR A 103 PHE A 105 MET A 106 PHE A 110 TYR A 116 ILE A 209 PRO A 210 ALA A 211 ALA A 287 ALA A 291 THR A 295 LEU A 356 MET A 360 MET A 460	X2N A1480
2X2N_B_X2NB1479	2x2n	X2N DB01263 (Posaconazole)	Trypanosoma brucei	LANOSTEROL 14-ALPHA-DEMETHYLASE	no annotation	13	TYR B 103 PHE B 105 MET B 106 PHE B 110 TYR B 116 PRO B 210 ALA B 211 ALA B 287 ALA B 291 THR B 295 LEU B 356 MET B 360 MET B 460	X2N B1479
2X2N_C_X2NC1479	2x2n	X2N DB01263 (Posaconazole)	Trypanosoma brucei	LANOSTEROL 14-ALPHA-DEMETHYLASE	no annotation	13	TYR C 103 PHE C 105 MET C 106 PHE C 110 TYR C 116 PRO C 210 VAL C 213 ALA C 287 ALA C 291 THR C 295 LEU C 356 MET C 360 MET C 460	X2N C1479
2X2N_D_X2ND1479	2x2n	X2N DB01263 (Posaconazole)	Trypanosoma brucei	LANOSTEROL 14-ALPHA-DEMETHYLASE	no annotation	13	ILE D 46 TYR D 103 PHE D 105 MET D 106 PHE D 110 TYR D 116 PRO D 210 ALA D 287 ALA D 291 THR D 295 LEU D 356 MET D 360 MET D 460	X2N D1479
4J14_A_X2NA602	4j14	X2N DB01263 (Posaconazole)	Homo sapiens	CHOLESTEROL 24-HYDROXYLASE	PF00067 (p450)	10	ALA A 111 LEU A 112 PHE A 121 VAL A 126 ARG A 226 ILE A 301 ALA A 302 THR A 306 ALA A 367 THR A 475	X2N A 602
4ZE1_A_X2NA602	4ze1	X2N DB01263 (Posaconazole)	Saccharomyces cerevisiae	LANOSTEROL 14-ALPHA DEMETHYLASE	PF00067 (p450)	17	VAL A 70 TYR A 72 GLY A 73 MET A 74 TYR A 126 LEU A 129 PHE A 134 ILE A 139 PHE A 236 PRO A 238 GLY A 314 THR A 318 LEU A 380 HIS A 381 PHE A 384 THR A 507 MET A 509	X2N A 602
5FSA_A_X2NA590	5fsa	X2N DB01263 (Posaconazole)	Candida albicans	CYP51 VARIANT1	PF00067 (p450)	15	ALA A 61 TYR A 64 TYR A 118 LEU A 121 PHE A 126 ILE A 131 PHE A 228 PRO A 230 PHE A 233 ILE A 304 GLY A 307 LEU A 376 HIS A 377 PHE A 380 SER A 506	X2N A 590
5FSA_B_X2NB590	5fsa	X2N DB01263 (Posaconazole)	Candida albicans	CYP51 VARIANT1	no annotation	15	TYR B 64 GLY B 65 GLN B 66 LEU B 121 PHE B 126 TYR B 132 PHE B 228 PRO B 230 ILE B 304 GLY B 307 THR B 311 LEU B 376 HIS B 377 PHE B 380 SER B 506	X2N B 590
5TL8_A_X2NA502	5tl8	X2N DB01263 (Posaconazole)	Naegleria fowleri	PROTEIN CYP51	no annotation	18	PHE A 53 ALA A 54 PRO A 57 TYR A 107 PHE A 109 PHE A 114 TYR A 120 PRO A 213 LEU A 214 PHE A 216 ALA A 289 ALA A 293 THR A 297 LEU A 358 MET A 360 MET A 362 THR A 465 LEU A 467	X2N A 502
6E8Q_A_X2NA602	6e8q	X2N DB01263 (Posaconazole)	Saccharomyces cerevisiae	LANOSTEROL 14-ALPHA DEMETHYLASE	PF00067 (p450)	16	TYR A 72 GLY A 73 TYR A 126 LEU A 129 PHE A 134 ILE A 139 TYR A 140 PHE A 236 PRO A 238 GLY A 314 THR A 318 LEU A 380 HIS A 381 PHE A 384 THR A 507 MET A 509	X2N A 602

[["2X2N_A_X2NA1480","2x2n","X2N","DB01263(Posaconazole)","Trypanosoma brucei","LANOSTEROL 14-ALPHA-DEMETHYLASE","PF00067(p450)",14,"TYR A 103;PHE A 105;MET A 106;PHE A 110;TYR A 116;ILE A 209;PRO A 210;ALA A 211;ALA A 287;ALA A 291;THR A 295;LEU A 356;MET A 360;MET A 460","X2N A1480\r"],["2X2N_B_X2NB1479","2x2n","X2N","DB01263(Posaconazole)","Trypanosoma brucei","LANOSTEROL 14-ALPHA-DEMETHYLASE","no annotation",13,"TYR B 103;PHE B 105;MET B 106;PHE B 110;TYR B 116;PRO B 210;ALA B 211;ALA B 287;ALA B 291;THR B 295;LEU B 356;MET B 360;MET B 460","X2N B1479\r"],["2X2N_C_X2NC1479","2x2n","X2N","DB01263(Posaconazole)","Trypanosoma brucei","LANOSTEROL 14-ALPHA-DEMETHYLASE","no annotation",13,"TYR C 103;PHE C 105;MET C 106;PHE C 110;TYR C 116;PRO C 210;VAL C 213;ALA C 287;ALA C 291;THR C 295;LEU C 356;MET C 360;MET C 460","X2N C1479\r"],["2X2N_D_X2ND1479","2x2n","X2N","DB01263(Posaconazole)","Trypanosoma brucei","LANOSTEROL 14-ALPHA-DEMETHYLASE","no annotation",13,"ILE D  46;TYR D 103;PHE D 105;MET D 106;PHE D 110;TYR D 116;PRO D 210;ALA D 287;ALA D 291;THR D 295;LEU D 356;MET D 360;MET D 460","X2N D1479\r"],["4J14_A_X2NA602","4j14","X2N","DB01263(Posaconazole)","Homo sapiens","CHOLESTEROL 24-HYDROXYLASE","PF00067(p450)",10,"ALA A 111;LEU A 112;PHE A 121;VAL A 126;ARG A 226;ILE A 301;ALA A 302;THR A 306;ALA A 367;THR A 475","X2N A 602\r"],["4ZE1_A_X2NA602","4ze1","X2N","DB01263(Posaconazole)","Saccharomyces cerevisiae","LANOSTEROL 14-ALPHA DEMETHYLASE","PF00067(p450)",17,"VAL A  70;TYR A  72;GLY A  73;MET A  74;TYR A 126;LEU A 129;PHE A 134;ILE A 139;PHE A 236;PRO A 238;GLY A 314;THR A 318;LEU A 380;HIS A 381;PHE A 384;THR A 507;MET A 509","X2N A 602\r"],["5FSA_A_X2NA590","5fsa","X2N","DB01263(Posaconazole)","Candida albicans","CYP51 VARIANT1","PF00067(p450)",15,"ALA A  61;TYR A  64;TYR A 118;LEU A 121;PHE A 126;ILE A 131;PHE A 228;PRO A 230;PHE A 233;ILE A 304;GLY A 307;LEU A 376;HIS A 377;PHE A 380;SER A 506","X2N A 590\r"],["5FSA_B_X2NB590","5fsa","X2N","DB01263(Posaconazole)","Candida albicans","CYP51 VARIANT1","no annotation",15,"TYR B  64;GLY B  65;GLN B  66;LEU B 121;PHE B 126;TYR B 132;PHE B 228;PRO B 230;ILE B 304;GLY B 307;THR B 311;LEU B 376;HIS B 377;PHE B 380;SER B 506","X2N B 590\r"],["5TL8_A_X2NA502","5tl8","X2N","DB01263(Posaconazole)","Naegleria fowleri","PROTEIN CYP51","no annotation",18,"PHE A  53;ALA A  54;PRO A  57;TYR A 107;PHE A 109;PHE A 114;TYR A 120;PRO A 213;LEU A 214;PHE A 216;ALA A 289;ALA A 293;THR A 297;LEU A 358;MET A 360;MET A 362;THR A 465;LEU A 467","X2N A 502\r"],["6E8Q_A_X2NA602","6e8q","X2N","DB01263(Posaconazole)","Saccharomyces cerevisiae","LANOSTEROL 14-ALPHA DEMETHYLASE","PF00067(p450)",16,"TYR A  72;GLY A  73;TYR A 126;LEU A 129;PHE A 134;ILE A 139;TYR A 140;PHE A 236;PRO A 238;GLY A 314;THR A 318;LEU A 380;HIS A 381;PHE A 384;THR A 507;MET A 509","X2N A 602\r"]]