DRUG BINDING INTERFACES MAPPED TO 'VIA'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1TBF_A_VIAA501	1tbf	VIA DB00203 (Sildenafil)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE	PF00233 (PDEase_I)	9	TYR A 612 LEU A 725 LEU A 765 VAL A 782 ALA A 783 LEU A 804 MET A 816 GLN A 817 PHE A 820	VIA A 501
1UDT_A_VIAA1000	1udt	VIA DB00203 (Sildenafil)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE	PF00233 (PDEase_I)	12	TYR A 612 HIS A 613 ASN A 661 TYR A 664 ALA A 767 ILE A 768 VAL A 782 ALA A 783 LEU A 804 MET A 816 GLN A 817 PHE A 820	VIA A1000
1XOS_A_VIAA1	1xos	VIA DB00203 (Sildenafil)	Homo sapiens	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B	PF00233 (PDEase_I)	14	TYR A 233 HIS A 234 MET A 347 ASP A 392 LEU A 393 ASN A 395 ILE A 410 MET A 411 PHE A 414 SER A 429 MET A 431 GLN A 443 PHE A 446 ILE A 450	VIA A 1
2H42_A_VIAA901	2h42	VIA DB00203 (Sildenafil)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE	PF00233 (PDEase_I)	11	TYR A 612 HIS A 613 ASN A 661 ALA A 767 ILE A 768 VAL A 782 PHE A 786 LEU A 804 ILE A 813 GLN A 817 PHE A 820	VIA A 901
2H42_B_VIAB902	2h42	VIA DB00203 (Sildenafil)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE	no annotation	12	TYR B 612 HIS B 613 ASN B 661 ALA B 767 ILE B 768 VAL B 782 ALA B 783 LEU B 804 ILE B 813 MET B 816 GLN B 817 PHE B 820	VIA B 902
2H42_C_VIAC903	2h42	VIA DB00203 (Sildenafil)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE	no annotation	15	TYR C 612 ASN C 661 ILE C 665 LEU C 725 LEU C 765 ALA C 767 ILE C 768 VAL C 782 ALA C 783 PHE C 786 LEU C 804 ILE C 813 MET C 816 GLN C 817 PHE C 820	VIA C 903
3JWQ_A_VIAA901	3jwq	VIA DB00203 (Sildenafil)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA	PF00233 (PDEase_I)	9	TYR A 612 HIS A 613 LEU A 725 VAL A 782 MET A 804 LEU A 813 GLN A 817 PHE A 820 VAL A 824	VIA A 901
3JWQ_B_VIAB901	3jwq	VIA DB00203 (Sildenafil)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA	no annotation	11	TYR B 612 HIS B 613 ASN B 661 LEU B 725 ALA B 767 VAL B 782 THR C 795 MET B 804 LEU B 813 GLN B 817 PHE B 820	VIA B 901
3JWQ_C_VIAC901	3jwq	VIA DB00203 (Sildenafil)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA	no annotation	7	TYR C 612 HIS C 613 MET C 804 LEU C 813 GLN C 817 PHE C 820 VAL C 824	VIA C 901
3JWQ_D_VIAD901	3jwq	VIA DB00203 (Sildenafil)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA	PF00233 (PDEase_I) no annotation	11	TYR D 612 HIS D 613 LEU D 725 ALA D 767 PHE D 786 ARG A 794 GLN A 798 MET D 804 LEU D 813 GLN D 817 PHE D 820	VIA D 901

[["1TBF_A_VIAA501","1tbf","VIA","DB00203(Sildenafil)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","PF00233(PDEase_I)",9,"TYR A 612;LEU A 725;LEU A 765;VAL A 782;ALA A 783;LEU A 804;MET A 816;GLN A 817;PHE A 820","VIA A 501\r"],["1UDT_A_VIAA1000","1udt","VIA","DB00203(Sildenafil)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","PF00233(PDEase_I)",12,"TYR A 612;HIS A 613;ASN A 661;TYR A 664;ALA A 767;ILE A 768;VAL A 782;ALA A 783;LEU A 804;MET A 816;GLN A 817;PHE A 820","VIA A1000\r"],["1XOS_A_VIAA1","1xos","VIA","DB00203(Sildenafil)","Homo sapiens","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B","PF00233(PDEase_I)",14,"TYR A 233;HIS A 234;MET A 347;ASP A 392;LEU A 393;ASN A 395;ILE A 410;MET A 411;PHE A 414;SER A 429;MET A 431;GLN A 443;PHE A 446;ILE A 450","VIA A   1\r"],["2H42_A_VIAA901","2h42","VIA","DB00203(Sildenafil)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","PF00233(PDEase_I)",11,"TYR A 612;HIS A 613;ASN A 661;ALA A 767;ILE A 768;VAL A 782;PHE A 786;LEU A 804;ILE A 813;GLN A 817;PHE A 820","VIA A 901\r"],["2H42_B_VIAB902","2h42","VIA","DB00203(Sildenafil)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","no annotation",12,"TYR B 612;HIS B 613;ASN B 661;ALA B 767;ILE B 768;VAL B 782;ALA B 783;LEU B 804;ILE B 813;MET B 816;GLN B 817;PHE B 820","VIA B 902\r"],["2H42_C_VIAC903","2h42","VIA","DB00203(Sildenafil)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","no annotation",15,"TYR C 612;ASN C 661;ILE C 665;LEU C 725;LEU C 765;ALA C 767;ILE C 768;VAL C 782;ALA C 783;PHE C 786;LEU C 804;ILE C 813;MET C 816;GLN C 817;PHE C 820","VIA C 903\r"],["3JWQ_A_VIAA901","3jwq","VIA","DB00203(Sildenafil)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","PF00233(PDEase_I)",9,"TYR A 612;HIS A 613;LEU A 725;VAL A 782;MET A 804;LEU A 813;GLN A 817;PHE A 820;VAL A 824","VIA A 901\r"],["3JWQ_B_VIAB901","3jwq","VIA","DB00203(Sildenafil)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","no annotation",11,"TYR B 612;HIS B 613;ASN B 661;LEU B 725;ALA B 767;VAL B 782;THR C 795;MET B 804;LEU B 813;GLN B 817;PHE B 820","VIA B 901\r"],["3JWQ_C_VIAC901","3jwq","VIA","DB00203(Sildenafil)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","no annotation",7,"TYR C 612;HIS C 613;MET C 804;LEU C 813;GLN C 817;PHE C 820;VAL C 824","VIA C 901\r"],["3JWQ_D_VIAD901","3jwq","VIA","DB00203(Sildenafil)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","PF00233(PDEase_I);no annotation",11,"TYR D 612;HIS D 613;LEU D 725;ALA D 767;PHE D 786;ARG A 794;GLN A 798;MET D 804;LEU D 813;GLN D 817;PHE D 820","VIA D 901\r"]]