DRUG BINDING INTERFACES MAPPED TO 'T27'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
2ZD1_A_T27A557
2zd1
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 557
2ZE2_A_T27A556
2ze2
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
10
PRO A 95ILE A 100ASN A 103VAL A 179TYR A 181TYR A 188PRO A 225TRP A 229LEU A 234TYR A 318
T27 A 556
3BGR_A_T27A556
3bgr
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
11
LEU A 100ASN A 103GLU B 138VAL A 179CYS A 181TYR A 183TYR A 188PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 556
3MEE_A_T27A561
3mee
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 REVERSETRANSCRIPTASE;P66 REVERSETRANSCRIPTASE
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
13
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 561
3MEG_A_T27A561
3meg
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 REVERSETRANSCRIPTASE;P66 REVERSETRANSCRIPTASE
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
13
PRO A 95LEU A 100LYS A 101ASN A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 561
3QLH_A_T27A555
3qlh
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
12
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229PRO A 236TYR A 318
T27 A 555
4G1Q_A_T27A601
4g1q
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
15
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4ICL_A_T27A601
4icl
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 601
4ID5_A_T27A601
4id5
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4IDK_A_T27A601
4idk
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 601
4IFV_A_T27A601
4ifv
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
EXORIBONUCLEASE H,P66 RT;GAG-POL POLYPROTEIN
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4IFY_A_T27A601
4ify
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4IG3_A_T27A601
4ig3
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 601
4KFB_A_T27A607
4kfb
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
P51 RT;REVERSETRANSCRIPTASE/RIBONUCLEASE H,EXORIBONUCLEA P66 RT
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
14
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318
T27 A 607
5CYM_A_T27A601
5cym
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
HIV-1 REVERSETRANSCRIPTASE, P51SUBUNIT;HIV-1 REVERSETRANSCRIPTASE, P66SUBUNIT
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
13
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 601
5CYQ_A_T27A601
5cyq
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
HIV-1 REVERSETRANSCRIPTASE, P51SUBUNIT;HIV-1 REVERSETRANSCRIPTASE, P66SUBUNIT
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)
13
PRO A 95LEU A 100LYS A 101LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 601
6ELI_A_T27A701
6eli
T27
DB08864(Rilpivirine)
Humanimmunodeficiency virus 1
GAG-POL POLYPROTEIN;REVERSETRANSCRIPTASE
no annotation
13
PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234TYR A 318
T27 A 701
[["2ZD1_A_T27A557","2zd1","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 557\r"],["2ZE2_A_T27A556","2ze2","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"PRO A 95;ILE A 100;ASN A 103;VAL A 179;TYR A 181;TYR A 188;PRO A 225;TRP A 229;LEU A 234;TYR A 318","T27 A 556\r"],["3BGR_A_T27A556","3bgr","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",11,"LEU A 100;ASN A 103;GLU B 138;VAL A 179;CYS A 181;TYR A 183;TYR A 188;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 556\r"],["3MEE_A_T27A561","3mee","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 REVERSE TRANSCRIPTASE;P66 REVERSE TRANSCRIPTASE","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",13,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 561\r"],["3MEG_A_T27A561","3meg","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 REVERSE TRANSCRIPTASE;P66 REVERSE TRANSCRIPTASE","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",13,"PRO A 95;LEU A 100;LYS A 101;ASN A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 561\r"],["3QLH_A_T27A555","3qlh","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",12,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;PRO A 236;TYR A 318","T27 A 555\r"],["4G1Q_A_T27A601","4g1q","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",15,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4ICL_A_T27A601","4icl","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 601\r"],["4ID5_A_T27A601","4id5","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4IDK_A_T27A601","4idk","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 601\r"],["4IFV_A_T27A601","4ifv","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","EXORIBONUCLEASE H, P66 RT;GAG-POL POLYPROTEIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4IFY_A_T27A601","4ify","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4IG3_A_T27A601","4ig3","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 601\r"],["4KFB_A_T27A607","4kfb","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","P51 RT;REVERSE TRANSCRIPTASE\/RIBONUCLEASE H, EXORIBONUCLEA P66 RT","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",14,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;PRO A 236;TYR A 318","T27 A 607\r"],["5CYM_A_T27A601","5cym","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT;HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",13,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 601\r"],["5CYQ_A_T27A601","5cyq","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT;HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",13,"PRO A 95;LEU A 100;LYS A 101;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 601\r"],["6ELI_A_T27A701","6eli","T27","DB08864(Rilpivirine)","Human immunodeficiency virus 1","GAG-POL POLYPROTEIN;REVERSE TRANSCRIPTASE","no annotation",13,"PRO A 95;LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;PRO A 225;PHE A 227;TRP A 229;LEU A 234;TYR A 318","T27 A 701\r"]]