DRUG BINDING INTERFACES MAPPED TO 'SVR'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1Y4L_B_SVRB301 | 1y4l | SVR DB04786(Suramin) | Bothrops asper | PHOSPHOLIPASE A2HOMOLOG 2 | PF00068(Phospholip_A2_1)no annotation | 24 | LEU B 2LEU A 2LEU B 5GLY A 23GLY A 30VAL B 31VAL A 31LEU A 32GLY A 33GLY B 33ARG B 34ARG A 34HIS B 48LYS B 49LYS A 49TYR A 52TYR B 52LYS A 53LYS B 53PRO A 68LYS B 69LYS A 69LYS A 70LYS B 70 | SVR B 301 |
2H9T_H_SVRH301 | 2h9t | SVR DB04786(Suramin) | Homo sapiens | THROMBIN | PF00089(Trypsin) | 11 | HIS H 91PRO H 92ARG H 93ARG H 101LYS H 236TRP H 237LYS H 240VAL H 241GLN H 244GLY H 246GLU H 247 | SVR H 301 |
2NYR_B_SVRB401 | 2nyr | SVR DB04786(Suramin) | Homo sapiens | NAD-DEPENDENTDEACETYLASESIRTUIN-5 | PF02146(SIR2)no annotation | 35 | ALA B 59ALA A 59THR A 69PHE A 70ARG B 71ARG A 71ALA B 82ALA A 82ALA B 86ALA A 86PHE A 101TYR B 102TYR A 102ARG A 105ARG B 105GLN B 140GLN A 140ASN A 141ILE A 142ILE B 142HIS B 158VAL B 220PHE A 223PHE B 223GLY B 224ASN A 226ASN B 226LEU A 227LEU B 232LEU A 232VAL B 254TYR A 255TYR B 255MET B 259MET A 259 | SVR B 401 |
3BF6_H_SVRH301 | 3bf6 | SVR DB04786(Suramin) | Homo sapiens | THROMBIN, HEAVYCHAIN | PF00089(Trypsin) | 11 | HIS H 91PRO H 92ARG H 93ARG H 101LYS H 236TRP H 237LYS H 240VAL H 241GLN H 244GLY H 246GLU H 247 | SVR H 301 |
3BJW_A_SVRA508 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | PF00068(Phospholip_A2_1)no annotation | 17 | VAL G 2VAL G 3VAL E 3GLY G 6LYS G 7GLN E 11PRO G 18PHE E 19THR G 23GLY G 30PRO A 36LYS G 69ARG E 72ARG G 72ARG E 77PHE A 124PHE H 124 | SVR A 508 |
3BJW_B_SVRB501 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | PF00068(Phospholip_A2_1)no annotation | 20 | VAL B 2LEU B 5GLY B 6ILE B 10LYS B 16SER A 17SER B 17PRO B 18PRO A 18PHE A 19PRO B 20PRO A 20SER B 21THR B 23LYS B 115LYS G 116LYS F 116ASN F 122PHE F 124TRP F 125 | SVR B 501 |
3BJW_B_SVRB512 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | PF00068(Phospholip_A2_1)no annotation | 21 | VAL A 2VAL B 3VAL A 3LYS B 7ILE B 10GLN B 11GLY B 14LYS G 16THR A 23THR A 70ARG A 72ARG B 107LEU B 110TYR G 113ASN G 114LYS G 115LYS G 116TYR G 117PRO G 121PHE G 124TRP G 125 | SVR B 512 |
3BJW_C_SVRC505 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | no annotation | 18 | VAL D 2VAL H 2VAL D 3VAL H 3GLU D 4GLY D 6LYS D 7GLN H 11PRO D 18PHE H 19THR D 23PRO C 36LYS D 69ARG D 72LYS D 74ARG H 77PHE E 124TRP E 125 | SVR C 505 |
3BJW_C_SVRC507 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | no annotation | 17 | VAL F 2VAL C 2VAL F 3VAL C 3GLY C 6GLN F 11PRO C 18PHE F 19PRO D 36LYS C 69ARG F 72ARG C 72LYS C 74ARG F 77PHE D 124PHE B 124TRP B 125 | SVR C 507 |
3BJW_E_SVRE503 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | PF00068(Phospholip_A2_1)no annotation | 20 | VAL E 2LEU E 5GLY E 6ILE E 10LYS E 16SER E 17SER G 17PRO E 18PRO G 18PHE G 19PRO E 20PRO G 20SER E 21THR E 23LYS E 115LYS H 116LYS A 116ASN H 122PHE H 124TRP H 125 | SVR E 503 |
3BJW_E_SVRE510 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | PF00068(Phospholip_A2_1)no annotation | 20 | VAL G 2VAL E 3VAL G 3LYS E 7GLN E 11GLY E 14LYS A 16THR G 23THR G 70ARG G 72ARG E 107LEU E 110TYR A 113ASN A 114LYS A 115LYS A 116TYR A 117PRO A 121PHE A 124TRP A 125 | SVR E 510 |
3BJW_F_SVRF502 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | no annotation | 22 | VAL F 2LEU F 5GLY F 6ILE F 10ILE C 10LYS F 16SER F 17SER C 17PRO F 18PRO C 18PHE F 19PHE C 19PRO F 20PRO C 20SER F 21THR F 23LYS F 115LYS B 116LYS D 116ASN B 122PHE B 124TRP B 125 | SVR F 502 |
3BJW_F_SVRF509 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | no annotation | 20 | VAL C 2VAL F 3VAL C 3LYS F 7ILE F 10GLN F 11GLY F 14LYS D 16THR C 23THR C 70ARG C 72ARG F 107LEU F 110TYR D 113ASN D 114LYS D 115LYS D 116PRO D 121PHE D 124TRP D 125 | SVR F 509 |
3BJW_G_SVRG506 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | PF00068(Phospholip_A2_1)no annotation | 18 | VAL B 2VAL A 2VAL B 3VAL A 3GLY A 6LYS A 7GLN B 11PRO A 18PHE B 19PRO G 36LYS A 69ARG A 72LYS A 74ARG B 77PHE G 124PHE F 124TRP F 125LYS G 127 | SVR G 506 |
3BJW_H_SVRH504 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | no annotation | 20 | VAL H 2LEU H 5GLY H 6ILE H 10LYS H 16SER D 17SER H 17PRO D 18PRO H 18PHE D 19PRO H 20PRO D 20SER H 21THR H 23LYS H 115LYS C 116PRO E 121ASN E 122PHE E 124TRP E 125 | SVR H 504 |
3BJW_H_SVRH511 | 3bjw | SVR DB04786(Suramin) | Echis carinatus | PHOSPHOLIPASE A2 | no annotation | 21 | VAL D 2VAL D 3VAL H 3LYS H 7ILE H 10GLN H 11GLY H 14LYS C 16THR D 23THR D 70ARG D 72ARG H 107LEU H 110TYR C 113ASN C 114LYS C 115LYS C 116TYR C 117PRO C 121PHE C 124TRP C 125 | SVR H 511 |
3GAN_A_SVRA158 | 3gan | SVR DB04786(Suramin) | Arabidopsisthaliana | UNCHARACTERIZEDPROTEIN AT3G22680 | PF09187(RdDM_RDM1) | 11 | ARG A 41TYR A 48GLN A 51VAL A 52PRO A 53PRO A 81TRP A 140TYR A 146ILE A 150ILE A 153PRO A 155 | SVR A 158 |
3PP7_B_SVRB499 | 3pp7 | SVR DB04786(Suramin) | Leishmaniamexicana | PYRUVATE KINASE | no annotation | 10 | THR B 26PRO B 29ARG B 49ASN B 51HIS B 54GLY B 55TYR B 59GLY B 331ALA B 334LYS B 335 | SVR B 499 |
3UR0_B_SVRB516 | 3ur0 | SVR DB04786(Suramin) | Norwalk virus | RNA-DEPENDENT RNAPOLYMERASE | no annotation | 7 | PRO B 38GLY B 40ALA B 41TRP B 42ALA B 409ASP B 412ARG B 413 | SVR B 516 |
3UR0_C_SVRC516 | 3ur0 | SVR DB04786(Suramin) | Norwalk virus | RNA-DEPENDENT RNAPOLYMERASE | no annotation | 9 | PRO C 38GLY C 40ALA C 41TRP C 42LYS C 171ALA C 409ASP C 412ARG C 413LEU C 416 | SVR C 516 |
3UR0_C_SVRC517 | 3ur0 | SVR DB04786(Suramin) | Norwalk virus | RNA-DEPENDENT RNAPOLYMERASE | no annotation | 11 | TRP C 42GLN C 66LYS C 68GLU C 168VAL C 170LYS C 171LYS C 174LYS C 180ARG C 182ARG C 245ARG C 392 | SVR C 517 |
4J4V_A_SVRA301 | 4j4v | SVR DB04786(Suramin) | SFTSphlebovirus | NUCLEOCAPSID PROTEIN | PF05733(Tenui_N) | 11 | GLY A 65ASN A 66LYS A 67ARG A 95ALA A 96VAL A 105GLN A 109PRO A 127MET A 147PHE A 177ILE A 181 | SVR A 301 |
4J4V_B_SVRB301 | 4j4v | SVR DB04786(Suramin) | SFTSphlebovirus | NUCLEOCAPSID PROTEIN | no annotation | 10 | GLY B 65ASN B 66LYS B 67ARG B 95ALA B 96VAL B 105GLN B 109PRO B 127MET B 147PHE B 177 | SVR B 301 |
4J4V_C_SVRC301 | 4j4v | SVR DB04786(Suramin) | SFTSphlebovirus | NUCLEOCAPSID PROTEIN | no annotation | 8 | GLY C 65ASN C 66LYS C 67ARG C 95PRO C 127MET C 147PHE C 177ILE C 181 | SVR C 301 |
4J4V_D_SVRD301 | 4j4v | SVR DB04786(Suramin) | SFTSphlebovirus | NUCLEOCAPSID PROTEIN | no annotation | 11 | GLY D 65ASN D 66LYS E 74ARG D 95ALA D 96VAL D 105GLN D 109PRO D 127MET D 147PHE D 177ILE D 181 | SVR D 301 |
4J4V_E_SVRE301 | 4j4v | SVR DB04786(Suramin) | SFTSphlebovirus | NUCLEOCAPSID PROTEIN | PF05733(Tenui_N)no annotation | 10 | GLY E 65ASN E 66LYS A 74ARG E 95ALA E 96VAL E 105GLN E 109PRO E 127MET E 147PHE E 177 | SVR E 301 |
4X3U_B_SVRB101 | 4x3u | SVR DB04786(Suramin) | Mus musculus | CHROMOBOX PROTEINHOMOLOG 7 | PF00385(Chromo)no annotation | 19 | ARG A 20ARG B 20ARG B 22LEU B 29LEU A 29TRP A 32TRP B 32TRP B 35TRP A 35TYR A 39TYR B 39THR A 41THR B 41TRP B 42TRP A 42HIS B 47HIS A 47LEU A 49LEU B 49 | SVR B 101 |
4X3U_B_SVRB102 | 4x3u | SVR DB04786(Suramin) | Mus musculus | CHROMOBOX PROTEINHOMOLOG 7 | PF00385(Chromo)no annotation | 3 | ARG B 20VAL B 21LYS A 23 | SVR B 102 |
4YV5_A_SVRA205 | 4yv5 | SVR DB04786(Suramin) | Bothropsmoojeni | BASIC PHOSPHOLIPASEA2 HOMOLOG 2 | PF00068(Phospholip_A2_1)no annotation | 13 | PHE B 3LYS B 7LEU B 10ASN B 17PRO B 18ARG B 72ASN A 114LYS A 115LYS A 116TYR A 119TYR A 121LEU A 122PHE A 126 | SVR A 205 |
4YV5_B_SVRB207 | 4yv5 | SVR DB04786(Suramin) | Bothropsmoojeni | BASIC PHOSPHOLIPASEA2 HOMOLOG 2 | PF00068(Phospholip_A2_1)no annotation | 13 | PHE A 3LYS A 7LEU A 10ASN A 17PRO A 18ARG A 72ASN B 114LYS B 115LYS B 116TYR B 119TYR B 121LEU B 122PHE B 126 | SVR B 207 |
6CE2_B_SVRB202 | 6ce2 | SVR DB04786(Suramin) | no annotation | 21 | LEU A 2LEU B 2LEU A 5LEU B 5GLY B 23GLY B 30LEU A 32GLY B 33GLY A 33ARG A 34ARG B 34LYS A 49LYS B 49TYR B 52TYR A 52LYS B 53ASN B 67PRO B 68LYS A 69LYS B 69LYS B 70 | SVR B 202 |