DRUG BINDING INTERFACES MAPPED TO 'RTZ'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
3TBG_A_RTZA1	3tbg	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	PF00067 (p450)	12	LEU A 110 PHE A 112 PHE A 120 LEU A 121 GLY A 212 LEU A 213 GLU A 216 GLN A 244 PHE A 247 ASP A 301 SER A 304 PHE A 483	RTZ A 1
3TBG_A_RTZA2	3tbg	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	PF00067 (p450)	11	THR A 54 LEU A 73 THR A 76 VAL A 78 SER A 217 GLU A 222 LEU A 372 VAL A 374 THR A 375 PHE A 481 PHE A 483	RTZ A 2
3TBG_B_RTZB1	3tbg	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	no annotation	12	LEU B 110 PHE B 112 PHE B 120 LEU B 121 GLY B 212 LEU B 213 GLU B 216 GLN B 244 PHE B 247 ALA B 300 ASP B 301 SER B 304	RTZ B 1
3TBG_B_RTZB2	3tbg	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	no annotation	8	LEU B 73 THR B 76 VAL B 78 GLU B 222 LEU B 372 THR B 375 ILE B 396 PHE B 483	RTZ B 2
3TBG_C_RTZC1	3tbg	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	no annotation	12	LEU C 110 PHE C 112 PHE C 120 LEU C 121 GLY C 212 LEU C 213 GLU C 216 GLN C 244 PHE C 247 ASP C 301 SER C 304 PHE C 483	RTZ C 1
3TBG_C_RTZC2	3tbg	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	no annotation	10	THR C 54 LEU C 73 THR C 76 VAL C 78 GLU C 222 LEU C 372 VAL C 374 THR C 375 PHE C 481 PHE C 483	RTZ C 2
3TBG_D_RTZD1	3tbg	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	no annotation	12	LEU D 110 PHE D 112 PHE D 120 LEU D 121 GLY D 212 LEU D 213 GLU D 216 GLN D 244 PHE D 247 ALA D 300 ASP D 301 SER D 304	RTZ D 1
3TBG_D_RTZD2	3tbg	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	no annotation	9	PHE D 58 LEU D 73 THR D 76 VAL D 78 GLU D 222 LEU D 372 THR D 375 ILE D 396 PHE D 483	RTZ D 2
4IAA_A_RTZA401	4iaa	RTZ DB00679 (Thioridazine)	Homo sapiens	SERINE/THREONINE-PRO TEIN KINASE PIM-1	PF00069 (Pkinase)	11	PHE A 49 VAL A 52 ALA A 65 LYS A 67 LEU A 120 VAL A 126 ASP A 128 GLU A 171 LEU A 174 ILE A 185 ASP A 186	RTZ A 401
4UHX_A_RTZA3009	4uhx	RTZ DB00679 (Thioridazine)	Homo sapiens	ALDEHYDE OXIDASE	PF00111 (Fer2) PF00941 (FAD_binding_5) PF01315 (Ald_Xan_dh_C) PF01799 (Fer2_2) PF02738 (Ald_Xan_dh_C2) PF03450 (CO_deh_flav_C)	8	HIS A 575 GLU A 577 ASP A 578 SER A1060 ARG A1061 ARG A1064 PRO A1066 TRP A1122	RTZ A3009
4WNW_A_RTZA602	4wnw	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	PF00067 (p450)	13	PHE A 112 PHE A 120 LEU A 121 GLY A 212 LEU A 213 GLU A 216 GLN A 244 ASP A 301 SER A 304 VAL A 308 THR A 309 VAL A 374 PHE A 483	RTZ A 602
4WNW_B_RTZB602	4wnw	RTZ DB00679 (Thioridazine)	Homo sapiens	CYTOCHROME P450 2D6	no annotation	15	PHE B 112 PHE B 120 LEU B 121 GLY B 212 LEU B 213 GLU B 216 GLN B 244 ILE B 297 ALA B 300 ASP B 301 SER B 304 ALA B 305 VAL B 308 VAL B 374 PHE B 483	RTZ B 602
6G95_B_RTZB708	6g95	RTZ DB00679 (Thioridazine)	Zaire ebolavirus	ENVELOPE GLYCOPROTEIN	no annotation	8	ILE A 38 LEU A 43 LEU A 184 LEU A 186 LEU B 515 MET B 548 LEU B 554 ILE B 555	RTZ B 708

[["3TBG_A_RTZA1","3tbg","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","PF00067(p450)",12,"LEU A 110;PHE A 112;PHE A 120;LEU A 121;GLY A 212;LEU A 213;GLU A 216;GLN A 244;PHE A 247;ASP A 301;SER A 304;PHE A 483","RTZ A   1\r"],["3TBG_A_RTZA2","3tbg","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","PF00067(p450)",11,"THR A  54;LEU A  73;THR A  76;VAL A  78;SER A 217;GLU A 222;LEU A 372;VAL A 374;THR A 375;PHE A 481;PHE A 483","RTZ A   2\r"],["3TBG_B_RTZB1","3tbg","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","no annotation",12,"LEU B 110;PHE B 112;PHE B 120;LEU B 121;GLY B 212;LEU B 213;GLU B 216;GLN B 244;PHE B 247;ALA B 300;ASP B 301;SER B 304","RTZ B   1\r"],["3TBG_B_RTZB2","3tbg","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","no annotation",8,"LEU B  73;THR B  76;VAL B  78;GLU B 222;LEU B 372;THR B 375;ILE B 396;PHE B 483","RTZ B   2\r"],["3TBG_C_RTZC1","3tbg","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","no annotation",12,"LEU C 110;PHE C 112;PHE C 120;LEU C 121;GLY C 212;LEU C 213;GLU C 216;GLN C 244;PHE C 247;ASP C 301;SER C 304;PHE C 483","RTZ C   1\r"],["3TBG_C_RTZC2","3tbg","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","no annotation",10,"THR C  54;LEU C  73;THR C  76;VAL C  78;GLU C 222;LEU C 372;VAL C 374;THR C 375;PHE C 481;PHE C 483","RTZ C   2\r"],["3TBG_D_RTZD1","3tbg","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","no annotation",12,"LEU D 110;PHE D 112;PHE D 120;LEU D 121;GLY D 212;LEU D 213;GLU D 216;GLN D 244;PHE D 247;ALA D 300;ASP D 301;SER D 304","RTZ D   1\r"],["3TBG_D_RTZD2","3tbg","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","no annotation",9,"PHE D  58;LEU D  73;THR D  76;VAL D  78;GLU D 222;LEU D 372;THR D 375;ILE D 396;PHE D 483","RTZ D   2\r"],["4IAA_A_RTZA401","4iaa","RTZ","DB00679(Thioridazine)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE PIM-1","PF00069(Pkinase)",11,"PHE A  49;VAL A  52;ALA A  65;LYS A  67;LEU A 120;VAL A 126;ASP A 128;GLU A 171;LEU A 174;ILE A 185;ASP A 186","RTZ A 401\r"],["4UHX_A_RTZA3009","4uhx","RTZ","DB00679(Thioridazine)","Homo sapiens","ALDEHYDE OXIDASE","PF00111(Fer2);PF00941(FAD_binding_5);PF01315(Ald_Xan_dh_C);PF01799(Fer2_2);PF02738(Ald_Xan_dh_C2);PF03450(CO_deh_flav_C)",8,"HIS A 575;GLU A 577;ASP A 578;SER A1060;ARG A1061;ARG A1064;PRO A1066;TRP A1122","RTZ A3009\r"],["4WNW_A_RTZA602","4wnw","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","PF00067(p450)",13,"PHE A 112;PHE A 120;LEU A 121;GLY A 212;LEU A 213;GLU A 216;GLN A 244;ASP A 301;SER A 304;VAL A 308;THR A 309;VAL A 374;PHE A 483","RTZ A 602\r"],["4WNW_B_RTZB602","4wnw","RTZ","DB00679(Thioridazine)","Homo sapiens","CYTOCHROME P450 2D6","no annotation",15,"PHE B 112;PHE B 120;LEU B 121;GLY B 212;LEU B 213;GLU B 216;GLN B 244;ILE B 297;ALA B 300;ASP B 301;SER B 304;ALA B 305;VAL B 308;VAL B 374;PHE B 483","RTZ B 602\r"],["6G95_B_RTZB708","6g95","RTZ","DB00679(Thioridazine)","Zaire ebolavirus","ENVELOPE GLYCOPROTEIN","no annotation",8,"ILE A  38;LEU A  43;LEU A 184;LEU A 186;LEU B 515;MET B 548;LEU B 554;ILE B 555","RTZ B 708\r"]]