DRUG BINDING INTERFACES MAPPED TO 'RIT'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1HXW_B_RITB301	1hxw	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	HIV-1 PROTEASE	PF00077 (RVP) no annotation	20	ARG B 8 LEU B 23 ASP A 25 ASP B 25 GLY B 27 GLY A 27 ALA B 28 ASP A 29 ASP A 30 ASP B 30 VAL B 32 GLY B 49 GLY A 49 ILE B 50 ILE A 50 PRO A 81 PRO B 81 VAL A 82 VAL B 82 ILE A 84	RIT B 301
1N49_B_RITB301	1n49	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	PROTEASE	PF00077 (RVP) no annotation	18	ARG B 8 ASN A 25 ASN B 25 GLY B 27 ALA B 28 ASP A 29 ASP B 30 VAL B 32 ILE B 47 GLY B 49 GLY A 49 ILE B 50 ILE A 50 PRO A 81 PRO B 81 ALA A 82 ILE A 84 ILE B 84	RIT B 301
1N49_D_RITD401	1n49	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	PROTEASE	no annotation	17	ARG C 8 ASN D 25 ASN C 25 GLY C 27 ALA C 28 ASP D 29 ASP C 30 VAL C 32 ILE C 47 GLY D 49 GLY C 49 ILE D 50 ILE C 50 PRO C 81 PRO D 81 ILE D 84 ILE C 84	RIT D 401
1RL8_A_RITA9001	1rl8	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	PROTEASE RETROPEPSIN	PF00077 (RVP) no annotation	24	ARG B 8 ARG A 8 LEU B 23 ASP A 25 ASP B 25 GLY A 27 GLY B 27 ALA B 28 ALA A 28 ASP A 29 ASP B 29 ASP B 30 ASP A 30 VAL A 32 GLY A 49 GLY B 49 ILE B 50 ILE A 50 PRO B 81 PRO A 81 ALA B 82 ALA A 82 ILE A 84 ILE B 84	RIT A9001
1SH9_B_RITB301	1sh9	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	POL POLYPROTEIN	PF00077 (RVP) no annotation	18	ARG B 8 ASP A 25 ASP B 25 GLY B 27 ALA A 28 ASP A 29 ASP B 30 ILE A 32 ILE B 32 ILE A 47 ILE B 47 GLY B 49 GLY A 49 ILE A 50 ILE B 50 PRO A 81 PRO B 81 ALA B 82	RIT B 301
2B60_B_RITB100	2b60	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	GAG-POL POLYPROTEIN	PF00077 (RVP) no annotation	23	ARG B 8 ARG A 8 ASP A 25 ASP B 25 GLY A 27 GLY B 27 ALA B 28 ALA A 28 ASP A 29 ASP B 29 ILE B 32 ILE A 32 ILE A 47 GLY A 49 GLY B 49 ILE B 50 ILE A 50 PRO B 81 PRO A 81 ALA B 82 ALA A 82 ILE A 84 ILE B 84	RIT B 100
3NDW_A_RITA100	3ndw	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	PROTEASE	PF00077 (RVP) no annotation	22	ARG B 8 ARG A 8 ASP A 25 ASP B 25 GLY A 27 ALA B 28 ALA A 28 ASP A 29 ASP B 29 ASP A 30 VAL A 32 ILE A 47 ILE B 47 GLY A 49 GLY B 49 ILE B 50 ILE A 50 PRO A 81 VAL A 82 VAL B 82 ILE A 84 ILE B 84	RIT A 100
3NDX_A_RITA100	3ndx	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	PROTEASE	PF00077 (RVP) no annotation	23	ARG B 8 ARG A 8 ASP A 25 ASP B 25 GLY A 27 GLY B 27 ALA B 28 ALA A 28 ASP A 29 ASP B 29 ASP B 30 ASP A 30 ILE A 47 ILE B 47 GLY A 49 GLY B 49 ILE B 50 ILE A 50 PRO A 81 VAL A 82 VAL B 82 ILE A 84 ILE B 84	RIT A 100
3NXU_A_RITA600	3nxu	RIT DB00503 (Ritonavir)	Homo sapiens	CYTOCHROME P450 3A4	PF00067 (p450)	19	PHE A 57 ARG A 105 PHE A 108 SER A 119 ILE A 120 LEU A 210 LEU A 211 PHE A 215 THR A 224 PHE A 241 ILE A 301 PHE A 304 ALA A 305 THR A 309 ILE A 369 ALA A 370 ARG A 372 GLU A 374 GLY A 481	RIT A 600
3NXU_B_RITB600	3nxu	RIT DB00503 (Ritonavir)	Homo sapiens	CYTOCHROME P450 3A4	no annotation	21	ARG B 105 PHE B 108 MET B 114 SER B 119 ILE B 120 LEU B 210 LEU B 211 PHE B 213 PHE B 215 THR B 224 PHE B 241 ILE B 301 PHE B 304 ALA B 305 THR B 309 ILE B 369 ALA B 370 ARG B 372 LEU B 373 GLU B 374 GLY B 481	RIT B 600
3PRS_A_RITA1001	3prs	RIT DB00503 (Ritonavir)	Cryphonectria parasitica	ENDOTHIAPEPSIN	PF00026 (Asp)	22	ILE A 10 ASP A 11 ASP A 15 ALA A 16 ASP A 33 ASP A 35 GLY A 37 ILE A 77 TYR A 79 GLY A 80 ASP A 81 ASP A 119 LEU A 125 THR A 135 PHE A 194 ILE A 217 ASP A 219 THR A 222 THR A 223 TYR A 226 ILE A 300 ILE A 304	RIT A1001
3Q70_A_RITA2001	3q70	RIT DB00503 (Ritonavir)	Candida albicans	CANDIDAPEPSIN-2	PF00026 (Asp)	18	THR A 13 ILE A 30 ASP A 32 GLY A 34 SER A 35 ILE A 82 TYR A 84 GLY A 85 SER A 88 ILE A 119 ASP A 120 ASN A 131 GLU A 193 ASP A 218 THR A 221 THR A 222 TYR A 225 ILE A 305	RIT A2001
3TNE_A_RITA401	3tne	RIT DB00503 (Ritonavir)	Candida parapsilosis	SECRETED ASPARTIC PROTEASE	PF00026 (Asp)	18	PRO A 12 ILE A 30 ASP A 32 GLY A 34 SER A 35 ILE A 76 TYR A 78 GLY A 79 ASP A 80 SER A 82 VAL A 113 ASP A 114 ASN A 125 ASP A 220 THR A 223 THR A 224 TYR A 227 ILE A 303	RIT A 401
3TNE_B_RITB401	3tne	RIT DB00503 (Ritonavir)	Candida parapsilosis	SECRETED ASPARTIC PROTEASE	PF00026 (Asp) no annotation	20	ILE B 30 ASP B 32 GLY B 34 SER B 35 LYS A 49 ILE B 76 TYR B 78 GLY B 79 ASP B 80 SER B 82 VAL B 113 ASP B 114 ILE B 117 ASN B 125 ASP B 220 THR B 223 THR B 224 TYR B 227 ASP B 301 ILE B 303	RIT B 401
4EYR_B_RITB301	4eyr	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	HIV-1 PROTEASE	PF00077 (RVP) no annotation	15	ARG B 8 LEU A 23 ASN A 25 ASN B 25 GLY B 27 ALA B 28 ALA A 28 ASP A 29 ASP B 29 ASP B 30 VAL A 32 ILE A 50 PRO B 81 THR A 82 THR B 82	RIT B 301
4NJV_A_RITA500	4njv	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	PROTEASE	PF00077 (RVP) no annotation	23	ARG B 8 ARG A 8 ASP A 25 ASP B 25 GLY A 27 GLY B 27 ALA A 28 ASP A 29 ASP B 29 ASP B 30 ASP A 30 VAL B 32 VAL A 32 GLY A 49 GLY B 49 ILE B 50 ILE A 50 PRO B 81 PRO A 81 THR A 82 THR B 82 ILE A 84 ILE B 84	RIT A 500
4NJV_D_RITD500	4njv	RIT DB00503 (Ritonavir)	Human immunodeficienc y virus 1	PROTEASE	no annotation	24	ARG D 8 ARG C 8 ASP D 25 ASP C 25 GLY C 27 GLY D 27 ALA D 28 ASP D 29 ASP C 29 ASP D 30 VAL C 32 VAL D 32 ILE D 47 ILE C 47 GLY D 49 GLY C 49 ILE D 50 ILE C 50 PRO D 81 PRO C 81 THR D 82 THR C 82 ILE D 84 ILE C 84	RIT D 500
5VC0_A_RITA602	5vc0	RIT DB00503 (Ritonavir)	Homo sapiens	CYTOCHROME P450 3A4	PF00067 (p450)	19	PHE A 57 ASP A 76 ARG A 105 ARG A 106 PHE A 108 SER A 119 ILE A 120 LEU A 210 LEU A 211 PHE A 213 PHE A 215 THR A 224 ILE A 301 PHE A 304 ALA A 305 THR A 309 ILE A 369 ALA A 370 ARG A 372	RIT A 602
5VCE_A_RITA602	5vce	RIT DB00503 (Ritonavir)	Homo sapiens	CYTOCHROME P450 3A4	PF00067 (p450)	18	ARG A 105 ARG A 106 PHE A 108 SER A 119 ILE A 120 ARG A 212 PHE A 213 PHE A 215 ILE A 223 THR A 224 PHE A 241 ILE A 301 PHE A 304 ALA A 305 THR A 309 ILE A 369 ALA A 370 GLU A 374	RIT A 602
5VEU_A_RITA602	5veu	RIT DB00503 (Ritonavir)	Homo sapiens	CYTOCHROME P450 3A5	no annotation	15	ARG A 105 ARG A 106 SER A 119 LEU A 120 PHE A 210 PHE A 213 PHE A 220 PHE A 241 ILE A 301 PHE A 304 ALA A 305 THR A 309 ALA A 370 GLY A 480 LEU A 481	RIT A 602
5VEU_B_RITB602	5veu	RIT DB00503 (Ritonavir)	Homo sapiens	CYTOCHROME P450 3A5	no annotation	14	ARG B 106 SER B 119 LEU B 120 PHE B 210 PHE B 215 PHE B 241 ILE B 301 PHE B 304 ALA B 305 THR B 309 ALA B 370 ILE B 371 GLU B 374 GLY B 480	RIT B 602
5VEU_H_RITH602	5veu	RIT DB00503 (Ritonavir)	Homo sapiens	CYTOCHROME P450 3A5	no annotation	17	ARG H 105 ARG H 106 SER H 119 LEU H 120 PHE H 210 PHE H 213 GLY H 214 PHE H 220 LEU H 240 PHE H 241 ILE H 301 PHE H 304 ALA H 305 THR H 309 GLU H 374 GLY H 480 LEU H 481	RIT H 602

[["1HXW_B_RITB301","1hxw","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP);no annotation",20,"ARG B   8;LEU B  23;ASP A  25;ASP B  25;GLY B  27;GLY A  27;ALA B  28;ASP A  29;ASP A  30;ASP B  30;VAL B  32;GLY B  49;GLY A  49;ILE B  50;ILE A  50;PRO A  81;PRO B  81;VAL A  82;VAL B  82;ILE A  84","RIT B 301\r"],["1N49_B_RITB301","1n49","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP);no annotation",18,"ARG B   8;ASN A  25;ASN B  25;GLY B  27;ALA B  28;ASP A  29;ASP B  30;VAL B  32;ILE B  47;GLY B  49;GLY A  49;ILE B  50;ILE A  50;PRO A  81;PRO B  81;ALA A  82;ILE A  84;ILE B  84","RIT B 301\r"],["1N49_D_RITD401","1n49","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","PROTEASE","no annotation",17,"ARG C   8;ASN D  25;ASN C  25;GLY C  27;ALA C  28;ASP D  29;ASP C  30;VAL C  32;ILE C  47;GLY D  49;GLY C  49;ILE D  50;ILE C  50;PRO C  81;PRO D  81;ILE D  84;ILE C  84","RIT D 401\r"],["1RL8_A_RITA9001","1rl8","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","PROTEASE RETROPEPSIN","PF00077(RVP);no annotation",24,"ARG B   8;ARG A   8;LEU B  23;ASP A  25;ASP B  25;GLY A  27;GLY B  27;ALA B  28;ALA A  28;ASP A  29;ASP B  29;ASP B  30;ASP A  30;VAL A  32;GLY A  49;GLY B  49;ILE B  50;ILE A  50;PRO B  81;PRO A  81;ALA B  82;ALA A  82;ILE A  84;ILE B  84","RIT A9001\r"],["1SH9_B_RITB301","1sh9","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","POL POLYPROTEIN","PF00077(RVP);no annotation",18,"ARG B   8;ASP A  25;ASP B  25;GLY B  27;ALA A  28;ASP A  29;ASP B  30;ILE A  32;ILE B  32;ILE A  47;ILE B  47;GLY B  49;GLY A  49;ILE A  50;ILE B  50;PRO A  81;PRO B  81;ALA B  82","RIT B 301\r"],["2B60_B_RITB100","2b60","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","GAG-POL POLYPROTEIN","PF00077(RVP);no annotation",23,"ARG B   8;ARG A   8;ASP A  25;ASP B  25;GLY A  27;GLY B  27;ALA B  28;ALA A  28;ASP A  29;ASP B  29;ILE B  32;ILE A  32;ILE A  47;GLY A  49;GLY B  49;ILE B  50;ILE A  50;PRO B  81;PRO A  81;ALA B  82;ALA A  82;ILE A  84;ILE B  84","RIT B 100\r"],["3NDW_A_RITA100","3ndw","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP);no annotation",22,"ARG B   8;ARG A   8;ASP A  25;ASP B  25;GLY A  27;ALA B  28;ALA A  28;ASP A  29;ASP B  29;ASP A  30;VAL A  32;ILE A  47;ILE B  47;GLY A  49;GLY B  49;ILE B  50;ILE A  50;PRO A  81;VAL A  82;VAL B  82;ILE A  84;ILE B  84","RIT A 100\r"],["3NDX_A_RITA100","3ndx","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP);no annotation",23,"ARG B   8;ARG A   8;ASP A  25;ASP B  25;GLY A  27;GLY B  27;ALA B  28;ALA A  28;ASP A  29;ASP B  29;ASP B  30;ASP A  30;ILE A  47;ILE B  47;GLY A  49;GLY B  49;ILE B  50;ILE A  50;PRO A  81;VAL A  82;VAL B  82;ILE A  84;ILE B  84","RIT A 100\r"],["3NXU_A_RITA600","3nxu","RIT","DB00503(Ritonavir)","Homo sapiens","CYTOCHROME P450 3A4","PF00067(p450)",19,"PHE A  57;ARG A 105;PHE A 108;SER A 119;ILE A 120;LEU A 210;LEU A 211;PHE A 215;THR A 224;PHE A 241;ILE A 301;PHE A 304;ALA A 305;THR A 309;ILE A 369;ALA A 370;ARG A 372;GLU A 374;GLY A 481","RIT A 600\r"],["3NXU_B_RITB600","3nxu","RIT","DB00503(Ritonavir)","Homo sapiens","CYTOCHROME P450 3A4","no annotation",21,"ARG B 105;PHE B 108;MET B 114;SER B 119;ILE B 120;LEU B 210;LEU B 211;PHE B 213;PHE B 215;THR B 224;PHE B 241;ILE B 301;PHE B 304;ALA B 305;THR B 309;ILE B 369;ALA B 370;ARG B 372;LEU B 373;GLU B 374;GLY B 481","RIT B 600\r"],["3PRS_A_RITA1001","3prs","RIT","DB00503(Ritonavir)","Cryphonectria parasitica","ENDOTHIAPEPSIN","PF00026(Asp)",22,"ILE A  10;ASP A  11;ASP A  15;ALA A  16;ASP A  33;ASP A  35;GLY A  37;ILE A  77;TYR A  79;GLY A  80;ASP A  81;ASP A 119;LEU A 125;THR A 135;PHE A 194;ILE A 217;ASP A 219;THR A 222;THR A 223;TYR A 226;ILE A 300;ILE A 304","RIT A1001\r"],["3Q70_A_RITA2001","3q70","RIT","DB00503(Ritonavir)","Candida albicans","CANDIDAPEPSIN-2","PF00026(Asp)",18,"THR A  13;ILE A  30;ASP A  32;GLY A  34;SER A  35;ILE A  82;TYR A  84;GLY A  85;SER A  88;ILE A 119;ASP A 120;ASN A 131;GLU A 193;ASP A 218;THR A 221;THR A 222;TYR A 225;ILE A 305","RIT A2001\r"],["3TNE_A_RITA401","3tne","RIT","DB00503(Ritonavir)","Candida parapsilosis","SECRETED ASPARTIC PROTEASE","PF00026(Asp)",18,"PRO A  12;ILE A  30;ASP A  32;GLY A  34;SER A  35;ILE A  76;TYR A  78;GLY A  79;ASP A  80;SER A  82;VAL A 113;ASP A 114;ASN A 125;ASP A 220;THR A 223;THR A 224;TYR A 227;ILE A 303","RIT A 401\r"],["3TNE_B_RITB401","3tne","RIT","DB00503(Ritonavir)","Candida parapsilosis","SECRETED ASPARTIC PROTEASE","PF00026(Asp);no annotation",20,"ILE B  30;ASP B  32;GLY B  34;SER B  35;LYS A  49;ILE B  76;TYR B  78;GLY B  79;ASP B  80;SER B  82;VAL B 113;ASP B 114;ILE B 117;ASN B 125;ASP B 220;THR B 223;THR B 224;TYR B 227;ASP B 301;ILE B 303","RIT B 401\r"],["4EYR_B_RITB301","4eyr","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP);no annotation",15,"ARG B   8;LEU A  23;ASN A  25;ASN B  25;GLY B  27;ALA B  28;ALA A  28;ASP A  29;ASP B  29;ASP B  30;VAL A  32;ILE A  50;PRO B  81;THR A  82;THR B  82","RIT B 301\r"],["4NJV_A_RITA500","4njv","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP);no annotation",23,"ARG B   8;ARG A   8;ASP A  25;ASP B  25;GLY A  27;GLY B  27;ALA A  28;ASP A  29;ASP B  29;ASP B  30;ASP A  30;VAL B  32;VAL A  32;GLY A  49;GLY B  49;ILE B  50;ILE A  50;PRO B  81;PRO A  81;THR A  82;THR B  82;ILE A  84;ILE B  84","RIT A 500\r"],["4NJV_D_RITD500","4njv","RIT","DB00503(Ritonavir)","Human immunodeficiency virus 1","PROTEASE","no annotation",24,"ARG D   8;ARG C   8;ASP D  25;ASP C  25;GLY C  27;GLY D  27;ALA D  28;ASP D  29;ASP C  29;ASP D  30;VAL C  32;VAL D  32;ILE D  47;ILE C  47;GLY D  49;GLY C  49;ILE D  50;ILE C  50;PRO D  81;PRO C  81;THR D  82;THR C  82;ILE D  84;ILE C  84","RIT D 500\r"],["5VC0_A_RITA602","5vc0","RIT","DB00503(Ritonavir)","Homo sapiens","CYTOCHROME P450 3A4","PF00067(p450)",19,"PHE A  57;ASP A  76;ARG A 105;ARG A 106;PHE A 108;SER A 119;ILE A 120;LEU A 210;LEU A 211;PHE A 213;PHE A 215;THR A 224;ILE A 301;PHE A 304;ALA A 305;THR A 309;ILE A 369;ALA A 370;ARG A 372","RIT A 602\r"],["5VCE_A_RITA602","5vce","RIT","DB00503(Ritonavir)","Homo sapiens","CYTOCHROME P450 3A4","PF00067(p450)",18,"ARG A 105;ARG A 106;PHE A 108;SER A 119;ILE A 120;ARG A 212;PHE A 213;PHE A 215;ILE A 223;THR A 224;PHE A 241;ILE A 301;PHE A 304;ALA A 305;THR A 309;ILE A 369;ALA A 370;GLU A 374","RIT A 602\r"],["5VEU_A_RITA602","5veu","RIT","DB00503(Ritonavir)","Homo sapiens","CYTOCHROME P450 3A5","no annotation",15,"ARG A 105;ARG A 106;SER A 119;LEU A 120;PHE A 210;PHE A 213;PHE A 220;PHE A 241;ILE A 301;PHE A 304;ALA A 305;THR A 309;ALA A 370;GLY A 480;LEU A 481","RIT A 602\r"],["5VEU_B_RITB602","5veu","RIT","DB00503(Ritonavir)","Homo sapiens","CYTOCHROME P450 3A5","no annotation",14,"ARG B 106;SER B 119;LEU B 120;PHE B 210;PHE B 215;PHE B 241;ILE B 301;PHE B 304;ALA B 305;THR B 309;ALA B 370;ILE B 371;GLU B 374;GLY B 480","RIT B 602\r"],["5VEU_H_RITH602","5veu","RIT","DB00503(Ritonavir)","Homo sapiens","CYTOCHROME P450 3A5","no annotation",17,"ARG H 105;ARG H 106;SER H 119;LEU H 120;PHE H 210;PHE H 213;GLY H 214;PHE H 220;LEU H 240;PHE H 241;ILE H 301;PHE H 304;ALA H 305;THR H 309;GLU H 374;GLY H 480;LEU H 481","RIT H 602\r"]]