DRUG BINDING INTERFACES MAPPED TO 'REA'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1CBR_A_REAA200 | 1cbr | REA DB00755(Tretinoin) | Mus musculus | CELLULAR RETINOICACID BINDING PROTEINTYPE I | PF00061(Lipocalin) | 12 | PHE A 15LEU A 28ALA A 32ALA A 36PRO A 39THR A 54THR A 56VAL A 58ARG A 59LEU A 120ARG A 131TYR A 133 | REA A 200 |
1CBR_B_REAB200 | 1cbr | REA DB00755(Tretinoin) | Mus musculus | CELLULAR RETINOICACID BINDING PROTEINTYPE I | PF00061(Lipocalin)no annotation | 13 | PHE B 15MET A 27LEU B 28ALA B 32ALA B 36PRO B 39THR B 54THR B 56VAL B 58ARG B 59LEU B 120ARG B 131TYR B 133 | REA B 200 |
1CBS_A_REAA200 | 1cbs | REA DB00755(Tretinoin) | Homo sapiens | CELLULAR RETINOICACID BINDING PROTEINTYPE II | PF00061(Lipocalin) | 13 | PHE A 15LEU A 19ILE A 31ALA A 32ALA A 36PRO A 39THR A 54THR A 56VAL A 58ARG A 59LEU A 121ARG A 132TYR A 134 | REA A 200 |
1FEM_A_REAA184 | 1fem | REA DB00755(Tretinoin) | Bos taurus | RETINOL BINDINGPROTEIN | PF00061(Lipocalin) | 10 | VAL A 61MET A 73PHE A 77MET A 88TYR A 90LEU A 97GLN A 98HIS A 104GLN A 117TYR A 133 | REA A 184 |
1GX9_A_REAA1163 | 1gx9 | REA DB00755(Tretinoin) | Bos taurus | BETA-LACTOGLOBULIN | PF00061(Lipocalin) | 11 | LEU A 39VAL A 41ILE A 56LYS A 60GLU A 62LYS A 69ILE A 71VAL A 92PHE A 105MET A 107GLN A 120 | REA A1163 |
1N4H_A_REAA500 | 1n4h | REA DB00755(Tretinoin) | Rattusnorvegicus | NUCLEAR RECEPTORROR-BETA | PF00104(Hormone_recep) | 11 | GLN A 21CYS A 55ILE A 59ALA A 62VAL A 96ARG A 99MET A 100ARG A 102VAL A 111LEU A 131ALA A 135 | REA A 500 |
1RLB_E_REAE176 | 1rlb | REA DB00755(Tretinoin) | Gallus gallus | RETINOL BINDINGPROTEIN | PF00061(Lipocalin) | 10 | LEU E 37ALA E 55ALA E 57VAL E 61MET E 73LEU E 97GLN E 98ASP E 102GLN E 117PHE E 135 | REA E 176 |
1RLB_F_REAF177 | 1rlb | REA DB00755(Tretinoin) | Gallus gallus | RETINOL BINDINGPROTEIN | no annotation | 11 | PHE F 36LEU F 37ALA F 55ALA F 57VAL F 61LEU F 63MET F 73MET F 88TYR F 90LEU F 97GLN F 98 | REA F 177 |
2ACL_A_REAA502 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep)no annotation | 12 | ALA A 271ALA A 272GLN A 275ASN A 306LEU A 309PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345CYS A 432LEU E 436 | REA A 502 |
2ACL_C_REAC503 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 10 | ILE C 268ALA C 271ALA C 272GLN C 275ASN C 306PHE C 313ARG C 316ALA C 327ILE C 345CYS C 432 | REA C 503 |
2ACL_E_REAE504 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 11 | ILE E 268ALA E 271ALA E 272GLN E 275ASN E 306LEU E 309PHE E 313ARG E 316ALA E 327ILE E 345CYS E 432 | REA E 504 |
2ACL_G_REAG501 | 2acl | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 13 | ILE G 268ALA G 271ALA G 272GLN G 275ASN G 306LEU G 309ILE G 310PHE G 313ARG G 316LEU G 326ALA G 327CYS G 432LEU C 436 | REA G 501 |
2FR3_A_REAA300 | 2fr3 | REA DB00755(Tretinoin) | Homo sapiens | CELLULAR RETINOICACID BINDING PROTEIN2 | PF00061(Lipocalin) | 13 | PHE A 15LEU A 19ILE A 31ALA A 32ALA A 36PRO A 39THR A 54THR A 56VAL A 58ARG A 59LEU A 121ARG A 132TYR A 134 | REA A 300 |
2G78_A_REAA200 | 2g78 | REA DB00755(Tretinoin) | Homo sapiens | CELLULAR RETINOICACID-BINDING PROTEIN2 | PF00061(Lipocalin) | 13 | PHE A 15LEU A 19ILE A 31ALA A 32THR A 54THR A 56VAL A 58ARG A 59VAL A 76ARG A 111LEU A 121MET A 123LYS A 132 | REA A 200 |
2LBD_A_REAA500 | 2lbd | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR GAMMA | PF00104(Hormone_recep) | 12 | PHE A 230LYS A 236CYS A 237LEU A 271MET A 272ARG A 274ILE A 275ARG A 278PHE A 288SER A 289GLY A 393LEU A 400 | REA A 500 |
2VE3_A_REAA1445 | 2ve3 | REA DB00755(Tretinoin) | Synechocystissp. PCC 6803 | PUTATIVE CYTOCHROMEP450 120 | PF00067(p450) | 12 | PHE A 29TRP A 80THR A 84ALA A 94PHE A 182LEU A 250PHE A 253ALA A 254THR A 258VAL A 318GLY A 319GLN A 345 | REA A1445 |
2VE3_B_REAB1445 | 2ve3 | REA DB00755(Tretinoin) | Synechocystissp. PCC 6803 | PUTATIVE CYTOCHROMEP450 120 | no annotation | 12 | PHE B 29TRP B 80THR B 84ALA B 94PHE B 182PHE B 253ALA B 254THR B 258VAL B 318GLY B 319GLN B 345PRO B 428 | REA B1445 |
3A9E_B_REAB1 | 3a9e | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR ALPHA | PF00104(Hormone_recep) | 11 | PHE B 228SER B 232CYS B 235LEU B 269ILE B 273ARG B 276PHE B 286SER B 287PHE B 302VAL B 395LEU B 398 | REA B 1 |
3CWK_A_REAA300 | 3cwk | REA DB00755(Tretinoin) | Homo sapiens | CELLULAR RETINOICACID-BINDING PROTEIN2 | PF00061(Lipocalin) | 13 | PHE A 15LEU A 19LEU A 28ILE A 31ALA A 32ALA A 36PRO A 39VAL A 54THR A 56VAL A 58ARG A 59GLU A 121LYS A 132 | REA A 300 |
3FAL_A_REAA501 | 3fal | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 10 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316ALA A 327VAL A 342ILE A 345CYS A 432 | REA A 501 |
3FAL_C_REAC501 | 3fal | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 10 | ILE C 268ALA C 271ALA C 272GLN C 275PHE C 313ARG C 316LEU C 326ALA C 327ILE C 345CYS C 432 | REA C 501 |
3FC6_A_REAA501 | 3fc6 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | PF00104(Hormone_recep) | 11 | ILE A 268ALA A 271ALA A 272GLN A 275TRP A 305PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345CYS A 432 | REA A 501 |
3FC6_C_REAC501 | 3fc6 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR RXR-ALPHA | no annotation | 14 | VAL C 265CYS C 269ALA C 271ALA C 272GLN C 275ASN C 306LEU C 309PHE C 313ARG C 316LEU C 326ALA C 327VAL C 342ILE C 345CYS C 432 | REA C 501 |
4DM8_A_REAA501 | 4dm8 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR BETA | PF00104(Hormone_recep) | 11 | PHE A 230CYS A 237LEU A 268LEU A 271ILE A 272ARG A 278PHE A 288SER A 289LEU A 307LEU A 400ILE A 412 | REA A 501 |
4DM8_B_REAB1501 | 4dm8 | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR BETA | no annotation | 14 | PHE B1201PHE B1230LEU B1233ALA B1234LEU B1268LEU B1271ILE B1272ARG B1278PHE B1288SER B1289PHE B1304LEU B1307GLY B1393LEU B1400 | REA B1501 |
4TNS_A_REAA201 | 4tns | REA DB00755(Tretinoin) | Homo sapiens | PEPTIDYL-PROLYLCIS-TRANS ISOMERASENIMA-INTERACTING 1 | PF00639(Rotamase) | 9 | HIS A 59LYS A 63ARG A 68ARG A 69MET A 130GLN A 131PHE A 134SER A 154HIS A 157 | REA A 201 |
5FHZ_A_REAA602 | 5fhz | REA DB00755(Tretinoin) | Homo sapiens | ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3 | PF00171(Aldedh) | 13 | ILE A 132GLY A 136ARG A 139THR A 140ASN A 181PHE A 182LEU A 185MET A 186TRP A 189CYS A 313CYS A 314THR A 315LEU A 471 | REA A 602 |
5FHZ_B_REAB602 | 5fhz | REA DB00755(Tretinoin) | Homo sapiens | ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3 | no annotation | 9 | ILE B 132GLY B 136THR B 140LEU B 185TRP B 189GLN B 304ASN B 469LEU B 471LEU B 489 | REA B 602 |
5FHZ_C_REAC602 | 5fhz | REA DB00755(Tretinoin) | Homo sapiens | ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3 | no annotation | 10 | ILE C 132GLY C 136THR C 140LEU C 185TRP C 189GLN C 304PHE C 308ASN C 469LEU C 471LEU C 489 | REA C 602 |
5FHZ_D_READ602 | 5fhz | REA DB00755(Tretinoin) | Homo sapiens | ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3 | no annotation | 12 | ILE D 132GLU D 135GLY D 136ARG D 139ASN D 181MET D 186TRP D 189GLU D 280CYS D 313CYS D 314THR D 315LEU D 471 | REA D 602 |
5UAN_B_REAB503 | 5uan | REA DB00755(Tretinoin) | Homo sapiens | RETINOIC ACIDRECEPTOR BETA | no annotation | 13 | PHE B 221ALA B 225CYS B 228LEU B 259LEU B 262ILE B 263ILE B 266PHE B 279SER B 280PHE B 295LEU B 298VAL B 388LEU B 391 | REA B 503 |
6EU9_B_REAB601 | 6eu9 | REA DB00755(Tretinoin) | Platynereisdumerilii | RETINOIC ACIDRECEPTOR | no annotation | 10 | ARG B 355VAL B 356LEU B 359SER B 360LEU B 394PHE B 414GLY B 428GLY B 519ARG B 522VAL B 523 | REA B 601 |
6EU9_D_READ601 | 6eu9 | REA DB00755(Tretinoin) | Platynereisdumerilii | RETINOIC ACIDRECEPTOR | no annotation | 7 | VAL D 356LEU D 394PHE D 414LEU D 420GLY D 428LEU D 433GLY D 519 | REA D 601 |