DRUG BINDING INTERFACES MAPPED TO 'PAC'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1FXH_B_PACB1001 1fxh PAC

DB09269
(Phenylacetic
acid)
Escherichia
coli
PENICILLIN ACYLASE PF01804
(Penicil_amidase)
7 SER B   1
PHE B  24
SER B  67
ALA B  69
MET A 142
PHE A 146
ILE B 177
PAC B1001
1K5Q_B_PACB559 1k5q PAC

DB09269
(Phenylacetic
acid)
Escherichia
coli
PENICILLIN G ACYLASE
ALPHA SUBUNIT;
PENICILLIN G ACYLASE
BETA SUBUNIT
PF01804
(Penicil_amidase)
7 SER B   1
PRO B  22
ALA B  24
TYR B  31
SER B  67
ALA B  69
MET A 142
PAC B 559
1PNL_B_PACB559 1pnl PAC

DB09269
(Phenylacetic
acid)
Escherichia
coli
PENICILLIN
AMIDOHYDROLASE
PF01804
(Penicil_amidase)
8 SER B   1
PHE B  24
SER B  67
ALA B  69
MET A 142
PHE A 146
ILE B 177
ASN B 241
PAC B 559
2INE_A_PACA317 2ine PAC

DB09269
(Phenylacetic
acid)
Homo sapiens ALDOSE REDUCTASE PF00248
(Aldo_ket_red)
5 TRP A  20
VAL A  47
TYR A  48
HIS A 110
TRP A 111
PAC A 317
2ISF_A_PACA317 2isf PAC

DB09269
(Phenylacetic
acid)
Homo sapiens ALDOSE REDUCTASE PF00248
(Aldo_ket_red)
5 TRP A  20
VAL A  47
TYR A  48
HIS A 110
TRP A 111
PAC A 317
2Y4N_B_PACB503 2y4n PAC

DB09269
(Phenylacetic
acid)
Burkholderia
cenocepacia
PHENYLACETATE-COENZY
ME A LIGASE
None 4 SER B  94
GLY B 137
GLY B 421
LYS B 422
PAC B 503
3IXL_A_PACA5000 3ixl PAC

DB09269
(Phenylacetic
acid)
Bordetella
bronchiseptica
ARYLMALONATE
DECARBOXYLASE
PF17645
(Amdase)
10 PRO A  14
CYS A  74
THR A  75
SER A  76
MET A 104
TYR A 126
VAL A 156
SER A 188
GLY A 189
GLY A 190
PAC A5000
4YFB_C_PACC601 4yfb PAC

DB09269
(Phenylacetic
acid)
Acidovorax sp.
MR-S7
PROTEIN RELATED TO
PENICILLIN ACYLASE
PF01804
(Penicil_amidase)
12 SER C   1
PRO C  22
TRP C  24
PHE C  32
PHE C  50
GLN C  57
ILE C  58
HIS C  68
VAL C  70
TRP C 165
TRP C 189
VAL C 190
PAC C 601
4YFB_F_PACF601 4yfb PAC

DB09269
(Phenylacetic
acid)
Acidovorax sp.
MR-S7
PROTEIN RELATED TO
PENICILLIN ACYLASE
None 12 SER F   1
PRO F  22
TRP F  24
PHE F  32
PHE F  50
GLN F  57
ILE F  58
HIS F  68
VAL F  70
TRP F 165
TRP F 189
VAL F 190
PAC F 601
4YFB_I_PACI601 4yfb PAC

DB09269
(Phenylacetic
acid)
Acidovorax sp.
MR-S7
PROTEIN RELATED TO
PENICILLIN ACYLASE
None 12 SER I   1
PRO I  22
TRP I  24
PHE I  32
PHE I  50
GLN I  57
ILE I  58
HIS I  68
VAL I  70
TRP I 165
TRP I 189
VAL I 190
PAC I 601
4YFB_L_PACL601 4yfb PAC

DB09269
(Phenylacetic
acid)
Acidovorax sp.
MR-S7
PROTEIN RELATED TO
PENICILLIN ACYLASE
None 12 SER L   1
PRO L  22
TRP L  24
PHE L  32
PHE L  50
GLN L  57
ILE L  58
HIS L  68
VAL L  70
TRP L 165
TRP L 189
VAL L 190
PAC L 601
5ZMQ_I_PACI1 5zmq PAC

DB09269
(Phenylacetic
acid)
Zika virus;
synthetic
construct
SERINE PROTEASE NS3;
SERINE PROTEASE
SUBUNIT NS2B;
PEPTIDE
PAC-DLY-DLY-DAR
None 3 GLU E  66
VAL D 155
TYR D 161
PAC I   1
5ZMQ_K_PACK1 5zmq PAC

DB09269
(Phenylacetic
acid)
Zika virus;
synthetic
construct
SERINE PROTEASE NS3;
PEPTIDE
PAC-DLY-DLY-DAR
None 3 ALA H 132
VAL H 155
TYR H 161
PAC K   1