DRUG BINDING INTERFACES MAPPED TO 'MFX'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
2XKK_E_MFXE1100	2xkk	MFX DB00218 (Moxifloxacin)	Acinetobacter baumannii; synthetic construct	DNA; TOPOISOMERASE IV	PF00521 (DNA_topoisoIV) PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	3	GLU C 437 SER C1084 ARG A1123	MFX E1100
3FOF_F_MFXF0	3fof	MFX DB00218 (Moxifloxacin)	; Streptococcus pneumoniae	DNA TOPOISOMERASE 4 SUBUNIT A	no annotation	3	GLY B 77 SER B 79 SER B 80	MFX F 0
3FOF_H_MFXH0	3fof	MFX DB00218 (Moxifloxacin)	; Streptococcus pneumoniae	DNA TOPOISOMERASE 4 SUBUNIT A; DNA TOPOISOMERASE 4 SUBUNIT B	PF00521 (DNA_topoisoIV) PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	4	GLY A 77 SER A 79 SER A 80 ARG C 456	MFX H 0
4Z2C_F_MFXF101	4z2c	MFX DB00218 (Moxifloxacin)	Escherichia coli; Streptococcus pneumoniae	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B; SYMMETRIZED E-SITE DNA	PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	4	SER B 81 ARG C 456 GLY C 457 GLU C 475	MFX F 101
4Z2C_H_MFXH101	4z2c	MFX DB00218 (Moxifloxacin)	Escherichia coli; Streptococcus pneumoniae	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B; SYMMETRIZED E-SITE DNA	PF00521 (DNA_topoisoIV) no annotation	4	SER A 81 ARG D 456 GLY D 457 GLU D 475	MFX H 101
4Z3O_F_MFXF101	4z3o	MFX DB00218 (Moxifloxacin)	Escherichia coli; Streptococcus pneumoniae	DNA TOPOISOMERASE 4 SUBUNIT B,PARE30-PARC55 FUSED TOPO IV FROM S. PNEUMONIAE; E-SITE DNA	PF00521 (DNA_topoisoIV) PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	5	ARG B 456 GLY B 457 GLU B 475 SER B1079 ARG A1117	MFX F 101
4Z3O_H_MFXH101	4z3o	MFX DB00218 (Moxifloxacin)	Escherichia coli; Streptococcus pneumoniae	DNA TOPOISOMERASE 4 SUBUNIT B,PARE30-PARC55 FUSED TOPO IV FROM S. PNEUMONIAE; E-SITE DNA	PF00521 (DNA_topoisoIV) PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	3	ARG A 456 GLU A 475 SER A1079	MFX H 101
5BS8_G_MFXG101	5bs8	MFX DB00218 (Moxifloxacin)	Mycobacterium tuberculosis; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B; DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC	PF00521 (DNA_topoisoIV) no annotation	7	ALA C 90 ARG A 128 ASP D 461 ARG D 482 GLY D 483 THR D 500 GLU D 501	MFX G 101
5BS8_H_MFXH101	5bs8	MFX DB00218 (Moxifloxacin)	Mycobacterium tuberculosis; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B; DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCAC GTAA	PF00521 (DNA_topoisoIV) PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	7	ALA A 90 ARG C 128 ASP B 461 ARG B 482 GLY B 483 THR B 500 GLU B 501	MFX H 101
5BTA_G_MFXG101	5bta	MFX DB00218 (Moxifloxacin)	Mycobacterium tuberculosis; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B; DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC	PF00521 (DNA_topoisoIV) no annotation	7	SER C 90 ARG A 128 ASP D 461 ARG D 482 GLY D 483 THR D 500 GLU D 501	MFX G 101
5BTA_H_MFXH101	5bta	MFX DB00218 (Moxifloxacin)	Mycobacterium tuberculosis; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B; DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCAC GTAA	PF00521 (DNA_topoisoIV) PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	6	SER A 90 ARG C 128 ARG B 482 GLY B 483 THR B 500 GLU B 501	MFX H 101
5CDQ_E_MFXE2101	5cdq	MFX DB00218 (Moxifloxacin)	Staphylococcus aureus; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B	PF00521 (DNA_topoisoIV) PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	5	SER A 84 ARG C 122 ARG B 458 GLY B 459 GLU B 477	MFX E2101
5CDQ_F_MFXF2101	5cdq	MFX DB00218 (Moxifloxacin)	Staphylococcus aureus; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B	PF00521 (DNA_topoisoIV) no annotation	6	SER C 84 ARG A 122 ASP D 437 ARG D 458 GLY D 459 GLU D 477	MFX F2101
5CDQ_V_MFXV2101	5cdq	MFX DB00218 (Moxifloxacin)	Staphylococcus aureus; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B	no annotation	5	SER R 84 ARG T 122 ARG S 458 GLY S 459 GLU S 477	MFX V2101
5CDQ_W_MFXW2101	5cdq	MFX DB00218 (Moxifloxacin)	Staphylococcus aureus; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B	no annotation	5	SER T 84 ARG R 122 ASP U 437 ARG U 458 GLU U 477	MFX W2101

[["2XKK_E_MFXE1100","2xkk","MFX","DB00218(Moxifloxacin)","Acinetobacter baumannii;synthetic construct","DNA;TOPOISOMERASE IV","PF00521(DNA_topoisoIV);PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",3,"GLU C 437;SER C1084;ARG A1123","MFX E1100\r"],["3FOF_F_MFXF0","3fof","MFX","DB00218(Moxifloxacin)",";Streptococcus pneumoniae","DNA TOPOISOMERASE 4 SUBUNIT A","no annotation",3,"GLY B  77;SER B  79;SER B  80","MFX F   0\r"],["3FOF_H_MFXH0","3fof","MFX","DB00218(Moxifloxacin)",";Streptococcus pneumoniae","DNA TOPOISOMERASE 4 SUBUNIT A;DNA TOPOISOMERASE 4 SUBUNIT B","PF00521(DNA_topoisoIV);PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",4,"GLY A  77;SER A  79;SER A  80;ARG C 456","MFX H   0\r"],["4Z2C_F_MFXF101","4z2c","MFX","DB00218(Moxifloxacin)","Escherichia coli;Streptococcus pneumoniae","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;SYMMETRIZED E-SITE DNA","PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",4,"SER B  81;ARG C 456;GLY C 457;GLU C 475","MFX F 101\r"],["4Z2C_H_MFXH101","4z2c","MFX","DB00218(Moxifloxacin)","Escherichia coli;Streptococcus pneumoniae","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;SYMMETRIZED E-SITE DNA","PF00521(DNA_topoisoIV);no annotation",4,"SER A  81;ARG D 456;GLY D 457;GLU D 475","MFX H 101\r"],["4Z3O_F_MFXF101","4z3o","MFX","DB00218(Moxifloxacin)","Escherichia coli;Streptococcus pneumoniae","DNA TOPOISOMERASE 4 SUBUNIT B,PARE30-PARC55 FUSED TOPO IV FROM S. PNEUMONIAE;E-SITE DNA","PF00521(DNA_topoisoIV);PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",5,"ARG B 456;GLY B 457;GLU B 475;SER B1079;ARG A1117","MFX F 101\r"],["4Z3O_H_MFXH101","4z3o","MFX","DB00218(Moxifloxacin)","Escherichia coli;Streptococcus pneumoniae","DNA TOPOISOMERASE 4 SUBUNIT B,PARE30-PARC55 FUSED TOPO IV FROM S. PNEUMONIAE;E-SITE DNA","PF00521(DNA_topoisoIV);PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",3,"ARG A 456;GLU A 475;SER A1079","MFX H 101\r"],["5BS8_G_MFXG101","5bs8","MFX","DB00218(Moxifloxacin)","Mycobacterium tuberculosis;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","PF00521(DNA_topoisoIV);no annotation",7,"ALA C  90;ARG A 128;ASP D 461;ARG D 482;GLY D 483;THR D 500;GLU D 501","MFX G 101\r"],["5BS8_H_MFXH101","5bs8","MFX","DB00218(Moxifloxacin)","Mycobacterium tuberculosis;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCACGTAA","PF00521(DNA_topoisoIV);PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",7,"ALA A  90;ARG C 128;ASP B 461;ARG B 482;GLY B 483;THR B 500;GLU B 501","MFX H 101\r"],["5BTA_G_MFXG101","5bta","MFX","DB00218(Moxifloxacin)","Mycobacterium tuberculosis;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","PF00521(DNA_topoisoIV);no annotation",7,"SER C  90;ARG A 128;ASP D 461;ARG D 482;GLY D 483;THR D 500;GLU D 501","MFX G 101\r"],["5BTA_H_MFXH101","5bta","MFX","DB00218(Moxifloxacin)","Mycobacterium tuberculosis;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCACGTAA","PF00521(DNA_topoisoIV);PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",6,"SER A  90;ARG C 128;ARG B 482;GLY B 483;THR B 500;GLU B 501","MFX H 101\r"],["5CDQ_E_MFXE2101","5cdq","MFX","DB00218(Moxifloxacin)","Staphylococcus aureus;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","PF00521(DNA_topoisoIV);PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",5,"SER A  84;ARG C 122;ARG B 458;GLY B 459;GLU B 477","MFX E2101\r"],["5CDQ_F_MFXF2101","5cdq","MFX","DB00218(Moxifloxacin)","Staphylococcus aureus;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","PF00521(DNA_topoisoIV);no annotation",6,"SER C  84;ARG A 122;ASP D 437;ARG D 458;GLY D 459;GLU D 477","MFX F2101\r"],["5CDQ_V_MFXV2101","5cdq","MFX","DB00218(Moxifloxacin)","Staphylococcus aureus;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","no annotation",5,"SER R  84;ARG T 122;ARG S 458;GLY S 459;GLU S 477","MFX V2101\r"],["5CDQ_W_MFXW2101","5cdq","MFX","DB00218(Moxifloxacin)","Staphylococcus aureus;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","no annotation",5,"SER T  84;ARG R 122;ASP U 437;ARG U 458;GLU U 477","MFX W2101\r"]]