DRUG BINDING INTERFACES MAPPED TO 'LOC'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
3E22_B_LOCB700	3e22	LOC DB01394 (Colchicine)	Bos taurus	TUBULIN ALPHA-1C CHAIN; TUBULIN BETA-2B CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	14	SER A 178 ALA A 180 VAL A 181 CYS B 241 LEU B 242 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 ALA B 316 VAL B 318 LYS B 352	LOC B 700
3E22_D_LOCD700	3e22	LOC DB01394 (Colchicine)	Bos taurus	TUBULIN ALPHA-1C CHAIN; TUBULIN BETA-2B CHAIN	no annotation	14	SER C 178 ALA C 180 VAL C 181 CYS D 241 LEU D 242 LEU D 248 ALA D 250 LYS D 254 LEU D 255 ASN D 258 MET D 259 ALA D 316 VAL D 318 LYS D 352	LOC D 700
3UT5_B_LOCB502	3ut5	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	14	ALA A 180 VAL A 181 CYS B 241 LEU B 242 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 THR B 314 ALA B 316 ILE B 318 LYS B 352 ILE B 378	LOC B 502
3UT5_D_LOCD502	3ut5	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	no annotation	14	ALA C 180 VAL C 181 CYS D 241 LEU D 242 GLN D 247 ALA D 250 LYS D 254 LEU D 255 ASN D 258 MET D 259 ALA D 316 LYS D 352 ALA D 354 ILE D 378	LOC D 502
4LZR_A_LOCA201	4lzr	LOC DB01394 (Colchicine)	Homo sapiens	BROMODOMAIN-CONTAINI NG PROTEIN 4	PF00439 (Bromodomain)	8	TRP A 81 VAL A 87 LEU A 92 LEU A 94 TYR A 139 ASN A 140 ASP A 144 ILE A 146	LOC A 201
4O2B_B_LOCB503	4o2b	LOC DB01394 (Colchicine)	Bos taurus	TUBULIN ALPHA-1B CHAIN; TUBULIN BETA-2B CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	16	SER A 178 ALA A 180 VAL A 181 CYS B 241 LEU B 242 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 THR B 314 ALA B 316 ILE B 318 LYS B 352 ILE B 378	LOC B 503
4O2B_D_LOCD503	4o2b	LOC DB01394 (Colchicine)	Bos taurus	TUBULIN ALPHA-1B CHAIN; TUBULIN BETA-2B CHAIN	no annotation	17	SER C 178 ALA C 180 VAL C 181 CYS D 241 LEU D 242 LEU D 248 ALA D 250 LYS D 254 LEU D 255 ASN D 258 MET D 259 THR D 314 ALA D 316 ILE D 318 LYS D 352 ALA D 354 ILE D 378	LOC D 503
4X1I_B_LOCB502	4x1i	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	15	SER A 178 ALA A 180 VAL A 181 CYS B 241 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 THR B 314 ALA B 316 VAL B 318 LYS B 352 ALA B 354	LOC B 502
4X1I_D_LOCD502	4x1i	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	no annotation	14	ALA C 180 VAL C 181 CYS D 241 LEU D 242 LEU D 248 LYS D 254 LEU D 255 ASN D 258 MET D 259 THR D 314 ALA D 316 LYS D 352 ALA D 354 ILE D 378	LOC D 502
4X1K_B_LOCB502	4x1k	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	12	SER A 178 VAL A 181 CYS B 241 LEU B 242 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 THR B 314 LYS B 352 ALA B 354	LOC B 502
4X1K_D_LOCD502	4x1k	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	no annotation	17	ASN C 101 SER C 178 ALA C 180 VAL C 181 CYS D 241 LEU D 242 LEU D 248 LYS D 254 LEU D 255 ASN D 258 MET D 259 THR D 314 ALA D 316 VAL D 318 LYS D 352 ALA D 354 ILE D 378	LOC D 502
4X1Y_B_LOCB502	4x1y	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	15	ALA A 180 VAL A 181 CYS B 241 LEU B 242 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 THR B 314 ALA B 316 VAL B 318 LYS B 352 ILE B 378	LOC B 502
4X1Y_D_LOCD502	4x1y	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	no annotation	16	SER C 178 ALA C 180 VAL C 181 CYS D 241 LEU D 242 LEU D 248 LYS D 254 LEU D 255 ASN D 258 MET D 259 THR D 314 ALA D 316 VAL D 318 LYS D 352 ALA D 354 ILE D 378	LOC D 502
4X20_B_LOCB502	4x20	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	16	SER A 178 VAL A 181 CYS B 241 LEU B 242 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 THR B 314 ALA B 316 VAL B 318 LYS B 352 ALA B 354 ILE B 378	LOC B 502
4X20_D_LOCD502	4x20	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	no annotation	14	SER C 178 ALA C 180 VAL C 181 LEU D 242 LEU D 248 LYS D 254 LEU D 255 ASN D 258 MET D 259 THR D 314 ALA D 316 VAL D 318 LYS D 352 ILE D 378	LOC D 502
5EYP_B_LOCB502	5eyp	LOC DB01394 (Colchicine)	Ovis aries	TUBULIN ALPHA CHAIN; TUBULIN BETA CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	17	SER A 178 ALA A 180 VAL A 181 CYS B 241 LEU B 242 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 THR B 314 ALA B 316 ILE B 318 LYS B 352 ALA B 354 ILE B 378	LOC B 502
5ITZ_B_LOCB502	5itz	LOC DB01394 (Colchicine)	Bos taurus	TUBULIN ALPHA-1B CHAIN; TUBULIN BETA-2B CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	15	ALA A 180 VAL A 181 CYS B 241 LEU B 242 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 THR B 314 ALA B 316 ILE B 318 LYS B 352 ILE B 378	LOC B 502
5MIO_B_LOCB502	5mio	LOC DB01394 (Colchicine)	Bos taurus; Ovis aries	TUBULIN ALPHA-1B CHAIN; TUBULIN BETA CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	15	ALA A 180 VAL A 181 CYS B 241 LEU B 242 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 THR B 314 ALA B 316 ILE B 318 LYS B 352 ILE B 378	LOC B 502
5NKN_A_LOCA201	5nkn	LOC DB01394 (Colchicine)	Homo sapiens	NEUTROPHIL GELATINASE-ASSOCIATE D LIPOCALIN	no annotation	15	GLY A 40 PHE A 41 VAL A 66 PHE A 68 LYS A 70 PHE A 71 MET A 73 MET A 79 LEU A 94 TRP A 106 ARG A 130 ASP A 132 PHE A 134 THR A 136 TYR A 138	LOC A 201
5NM5_B_LOCB502	5nm5	LOC DB01394 (Colchicine)	Bos taurus	TUBULIN ALPHA-1B CHAIN; TUBULIN BETA-2B CHAIN	PF00091 (Tubulin) PF03953 (Tubulin_C)	18	ASN A 101 SER A 178 ALA A 180 VAL A 181 CYS B 241 LEU B 242 LEU B 248 ALA B 250 LYS B 254 LEU B 255 ASN B 258 MET B 259 THR B 314 ALA B 316 ILE B 318 LYS B 352 ALA B 354 ILE B 378	LOC B 502
5XIW_B_LOCB504	5xiw	LOC DB01394 (Colchicine)	Sus scrofa	TUBULIN ALPHA-1B CHAIN; TUBULIN BETA CHAIN	no annotation	17	SER A 178 ALA A 180 VAL A 181 CYS B 239 LEU B 240 LEU B 246 ALA B 248 LYS B 252 LEU B 253 ASN B 256 MET B 257 THR B 312 ALA B 314 ILE B 316 LYS B 350 ALA B 352 ILE B 368	LOC B 504
5XIW_D_LOCD503	5xiw	LOC DB01394 (Colchicine)	Sus scrofa	TUBULIN ALPHA-1B CHAIN; TUBULIN BETA CHAIN	no annotation	17	SER C 178 ALA C 180 VAL C 181 CYS D 239 LEU D 240 LEU D 246 ALA D 248 LYS D 252 LEU D 253 ASN D 256 MET D 257 THR D 312 ALA D 314 ILE D 316 LYS D 350 ALA D 352 ILE D 368	LOC D 503

[["3E22_B_LOCB700","3e22","LOC","DB01394(Colchicine)","Bos taurus","TUBULIN ALPHA-1C CHAIN;TUBULIN BETA-2B CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",14,"SER A 178;ALA A 180;VAL A 181;CYS B 241;LEU B 242;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;ALA B 316;VAL B 318;LYS B 352","LOC B 700\r"],["3E22_D_LOCD700","3e22","LOC","DB01394(Colchicine)","Bos taurus","TUBULIN ALPHA-1C CHAIN;TUBULIN BETA-2B CHAIN","no annotation",14,"SER C 178;ALA C 180;VAL C 181;CYS D 241;LEU D 242;LEU D 248;ALA D 250;LYS D 254;LEU D 255;ASN D 258;MET D 259;ALA D 316;VAL D 318;LYS D 352","LOC D 700\r"],["3UT5_B_LOCB502","3ut5","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",14,"ALA A 180;VAL A 181;CYS B 241;LEU B 242;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;THR B 314;ALA B 316;ILE B 318;LYS B 352;ILE B 378","LOC B 502\r"],["3UT5_D_LOCD502","3ut5","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","no annotation",14,"ALA C 180;VAL C 181;CYS D 241;LEU D 242;GLN D 247;ALA D 250;LYS D 254;LEU D 255;ASN D 258;MET D 259;ALA D 316;LYS D 352;ALA D 354;ILE D 378","LOC D 502\r"],["4LZR_A_LOCA201","4lzr","LOC","DB01394(Colchicine)","Homo sapiens","BROMODOMAIN-CONTAINING PROTEIN 4","PF00439(Bromodomain)",8,"TRP A  81;VAL A  87;LEU A  92;LEU A  94;TYR A 139;ASN A 140;ASP A 144;ILE A 146","LOC A 201\r"],["4O2B_B_LOCB503","4o2b","LOC","DB01394(Colchicine)","Bos taurus","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",16,"SER A 178;ALA A 180;VAL A 181;CYS B 241;LEU B 242;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;THR B 314;ALA B 316;ILE B 318;LYS B 352;ILE B 378","LOC B 503\r"],["4O2B_D_LOCD503","4o2b","LOC","DB01394(Colchicine)","Bos taurus","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN","no annotation",17,"SER C 178;ALA C 180;VAL C 181;CYS D 241;LEU D 242;LEU D 248;ALA D 250;LYS D 254;LEU D 255;ASN D 258;MET D 259;THR D 314;ALA D 316;ILE D 318;LYS D 352;ALA D 354;ILE D 378","LOC D 503\r"],["4X1I_B_LOCB502","4x1i","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",15,"SER A 178;ALA A 180;VAL A 181;CYS B 241;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;THR B 314;ALA B 316;VAL B 318;LYS B 352;ALA B 354","LOC B 502\r"],["4X1I_D_LOCD502","4x1i","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","no annotation",14,"ALA C 180;VAL C 181;CYS D 241;LEU D 242;LEU D 248;LYS D 254;LEU D 255;ASN D 258;MET D 259;THR D 314;ALA D 316;LYS D 352;ALA D 354;ILE D 378","LOC D 502\r"],["4X1K_B_LOCB502","4x1k","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",12,"SER A 178;VAL A 181;CYS B 241;LEU B 242;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;THR B 314;LYS B 352;ALA B 354","LOC B 502\r"],["4X1K_D_LOCD502","4x1k","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","no annotation",17,"ASN C 101;SER C 178;ALA C 180;VAL C 181;CYS D 241;LEU D 242;LEU D 248;LYS D 254;LEU D 255;ASN D 258;MET D 259;THR D 314;ALA D 316;VAL D 318;LYS D 352;ALA D 354;ILE D 378","LOC D 502\r"],["4X1Y_B_LOCB502","4x1y","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",15,"ALA A 180;VAL A 181;CYS B 241;LEU B 242;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;THR B 314;ALA B 316;VAL B 318;LYS B 352;ILE B 378","LOC B 502\r"],["4X1Y_D_LOCD502","4x1y","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","no annotation",16,"SER C 178;ALA C 180;VAL C 181;CYS D 241;LEU D 242;LEU D 248;LYS D 254;LEU D 255;ASN D 258;MET D 259;THR D 314;ALA D 316;VAL D 318;LYS D 352;ALA D 354;ILE D 378","LOC D 502\r"],["4X20_B_LOCB502","4x20","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",16,"SER A 178;VAL A 181;CYS B 241;LEU B 242;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;THR B 314;ALA B 316;VAL B 318;LYS B 352;ALA B 354;ILE B 378","LOC B 502\r"],["4X20_D_LOCD502","4x20","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","no annotation",14,"SER C 178;ALA C 180;VAL C 181;LEU D 242;LEU D 248;LYS D 254;LEU D 255;ASN D 258;MET D 259;THR D 314;ALA D 316;VAL D 318;LYS D 352;ILE D 378","LOC D 502\r"],["5EYP_B_LOCB502","5eyp","LOC","DB01394(Colchicine)","Ovis aries","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",17,"SER A 178;ALA A 180;VAL A 181;CYS B 241;LEU B 242;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;THR B 314;ALA B 316;ILE B 318;LYS B 352;ALA B 354;ILE B 378","LOC B 502\r"],["5ITZ_B_LOCB502","5itz","LOC","DB01394(Colchicine)","Bos taurus","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",15,"ALA A 180;VAL A 181;CYS B 241;LEU B 242;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;THR B 314;ALA B 316;ILE B 318;LYS B 352;ILE B 378","LOC B 502\r"],["5MIO_B_LOCB502","5mio","LOC","DB01394(Colchicine)","Bos taurus;Ovis aries","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",15,"ALA A 180;VAL A 181;CYS B 241;LEU B 242;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;THR B 314;ALA B 316;ILE B 318;LYS B 352;ILE B 378","LOC B 502\r"],["5NKN_A_LOCA201","5nkn","LOC","DB01394(Colchicine)","Homo sapiens","NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN","no annotation",15,"GLY A  40;PHE A  41;VAL A  66;PHE A  68;LYS A  70;PHE A  71;MET A  73;MET A  79;LEU A  94;TRP A 106;ARG A 130;ASP A 132;PHE A 134;THR A 136;TYR A 138","LOC A 201\r"],["5NM5_B_LOCB502","5nm5","LOC","DB01394(Colchicine)","Bos taurus","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN","PF00091(Tubulin);PF03953(Tubulin_C)",18,"ASN A 101;SER A 178;ALA A 180;VAL A 181;CYS B 241;LEU B 242;LEU B 248;ALA B 250;LYS B 254;LEU B 255;ASN B 258;MET B 259;THR B 314;ALA B 316;ILE B 318;LYS B 352;ALA B 354;ILE B 378","LOC B 502\r"],["5XIW_B_LOCB504","5xiw","LOC","DB01394(Colchicine)","Sus scrofa","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA CHAIN","no annotation",17,"SER A 178;ALA A 180;VAL A 181;CYS B 239;LEU B 240;LEU B 246;ALA B 248;LYS B 252;LEU B 253;ASN B 256;MET B 257;THR B 312;ALA B 314;ILE B 316;LYS B 350;ALA B 352;ILE B 368","LOC B 504\r"],["5XIW_D_LOCD503","5xiw","LOC","DB01394(Colchicine)","Sus scrofa","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA CHAIN","no annotation",17,"SER C 178;ALA C 180;VAL C 181;CYS D 239;LEU D 240;LEU D 246;ALA D 248;LYS D 252;LEU D 253;ASN D 256;MET D 257;THR D 312;ALA D 314;ILE D 316;LYS D 350;ALA D 352;ILE D 368","LOC D 503\r"]]