DRUG BINDING INTERFACES MAPPED TO 'IVM'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
3JAF_A_IVMA503 | 3jaf | IVM DB00602(Ivermectin) | Danio rerio | GLYCINE RECEPTORSUBUNIT ALPHAZ1 | PF02932(Neur_chan_memb)PF02931(Neur_chan_LBD) | 13 | LEU B 240ILE B 241ILE B 245PRO B 246LEU B 248LEU B 249ILE B 252THR A 280SER A 283ARG A 287VAL A 296ALA A 304LEU A 307 | IVM A 503 |
3RHW_A_IVMA348 | 3rhw | IVM DB00602(Ivermectin) | Caenorhabditiselegans | AVERMECTIN-SENSITIVEGLUTAMATE-GATEDCHLORIDE CHANNELGLUCL ALPHA | PF02932(Neur_chan_memb)PF02931(Neur_chan_LBD) | 13 | LEU A 217GLN A 219ILE A 222PRO A 223MET A 226THR E 257SER E 260ILE E 273ILE E 280GLY E 281MET E 284THR E 285PHE E 288 | IVM A 348 |
3RI5_A_IVMA349 | 3ri5 | IVM DB00602(Ivermectin) | Caenorhabditiselegans | AVERMECTIN-SENSITIVEGLUTAMATE-GATEDCHLORIDE CHANNELGLUCL ALPHA | PF02932(Neur_chan_memb)PF02931(Neur_chan_LBD) | 15 | LEU A 217GLN A 219ILE A 222PRO A 223MET A 226ILE A 229THR E 257SER E 260ASN E 264ILE E 273ILE E 280GLY E 281MET E 284THR E 285PHE E 288 | IVM A 349 |
3RIA_A_IVMA348 | 3ria | IVM DB00602(Ivermectin) | Caenorhabditiselegans | AVERMECTIN-SENSITIVEGLUTAMATE-GATEDCHLORIDE CHANNELGLUCL ALPHA | PF02931(Neur_chan_LBD)PF02932(Neur_chan_memb) | 13 | LEU B 217GLN B 219ILE B 222PRO B 223MET B 226THR A 257SER A 260ILE A 273ILE A 280GLY A 281MET A 284THR A 285PHE A 288 | IVM A 348 |
3RIF_A_IVMA402 | 3rif | IVM DB00602(Ivermectin) | Caenorhabditiselegans | AVERMECTIN-SENSITIVEGLUTAMATE-GATEDCHLORIDE CHANNELGLUCL ALPHA | PF02932(Neur_chan_memb)PF02931(Neur_chan_LBD) | 14 | LEU B 217GLN B 219ILE B 222PRO B 223MET B 226THR A 257SER A 260ASN A 264ILE A 273ILE A 280GLY A 281MET A 284THR A 285PHE A 288 | IVM A 402 |
4WVD_A_IVMA505 | 4wvd | IVM DB00602(Ivermectin) | Homo sapiens | BILE ACID RECEPTOR | PF00104(Hormone_recep) | 11 | GLU A 276ASN A 283LEU A 287MET A 290ASN A 293HIS A 294ARG A 331SER A 332ILE A 335LEU A 348MET A 365 | IVM A 505 |
5VDH_A_IVMA403 | 5vdh | IVM DB00602(Ivermectin) | Homo sapiens | GLYCINE RECEPTORSUBUNIT ALPHA-3 | PF02932(Neur_chan_memb)PF02931(Neur_chan_LBD) | 12 | LEU B 224GLN B 226ILE B 229PRO B 230LEU B 233THR A 264SER A 267SER A 268VAL A 280ALA A 288LEU A 291LEU A 292 | IVM A 403 |
5VDI_A_IVMA403 | 5vdi | IVM DB00602(Ivermectin) | Homo sapiens | GLYCINE RECEPTORSUBUNIT ALPHA-3 | PF02931(Neur_chan_LBD)PF02932(Neur_chan_memb) | 10 | GLN B 226ILE B 229PRO B 230LEU B 233ILE B 236THR A 264SER A 267VAL A 280ALA A 288LEU A 291 | IVM A 403 |