DRUG BINDING INTERFACES MAPPED TO 'FI8'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
6BZO_C_FI8C1201	6bzo	FI8 DB08874 (Fidaxomicin)	Mycobacterium tuberculosis	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'; RNA POLYMERASE SIGMA FACTOR SIGA; RNA POLYMERASE-BINDING PROTEIN RBPA	PF00140 (Sigma70_r1_2) PF04539 (Sigma70_r3) PF04542 (Sigma70_r2) PF04545 (Sigma70_r4) PF00562 (RNA_pol_Rpb2_7) PF04560 (RNA_pol_Rpb2_3) PF04561 (RNA_pol_Rpb2_45) PF04565 (RNA_pol_Rpb2_6) PF10385 (RNA_pol_Rpb2_2) PF00623 (RNA_pol_Rpb1_3) PF04983 (RNA_pol_Rpb1_5) PF04997 (RNA_pol_Rpb1_4) PF04998 (RNA_pol_Rpb1_2) PF05000 (RNA_pol_Rpb1_1) PF13397 (RbpA)	28	ARG J 10 VAL J 14 ARG D 84 LYS D 86 ARG D 89 GLU D 323 LEU D 324 PRO D 326 SER D 338 ARG D 412 GLN D 415 LEU F 423 ASP F 424 GLN F 434 VAL F 445 MET C1051 ILE C1052 THR C1053 GLN C1054 ASP C1094 THR C1096 VAL C1097 VAL C1100 LYS C1101 GLU C1119 SER C1120 VAL C1123 GLU C1127	FI8 C1201
6C06_D_FI8D1404	6c06	FI8 DB08874 (Fidaxomicin)	Mycobacterium tuberculosis	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'; RNA POLYMERASE SIGMA FACTOR SIGA; RNA POLYMERASE-BINDING PROTEIN RBPA	PF00140 (Sigma70_r1_2) PF04539 (Sigma70_r3) PF04542 (Sigma70_r2) PF04545 (Sigma70_r4) PF00562 (RNA_pol_Rpb2_7) PF04560 (RNA_pol_Rpb2_3) PF04561 (RNA_pol_Rpb2_45) PF04565 (RNA_pol_Rpb2_6) PF10385 (RNA_pol_Rpb2_2) PF00623 (RNA_pol_Rpb1_3) PF04983 (RNA_pol_Rpb1_2) PF04997 (RNA_pol_Rpb1_4) PF04998 (RNA_pol_Rpb1_5) PF05000 (RNA_pol_Rpb1_1) PF13397 (RbpA)	13	ARG J 10 ARG D 84 LYS D 86 ARG D 412 GLN F 434 ILE C1052 THR C1053 GLN C1054 THR C1096 ARG C1099 LYS C1101 GLU C1119 SER C1120	FI8 D1404
6FBV_D_FI8D1904	6fbv	FI8 DB08874 (Fidaxomicin)	Mycobacterium tuberculosis	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'; RNA POLYMERASE SIGMA FACTOR SIGA	PF00140 (Sigma70_r1_2) PF00562 (RNA_pol_Rpb2_45) PF04560 (RNA_pol_Rpb2_7) PF04561 (RNA_pol_Rpb2_2) PF04565 (RNA_pol_Rpb2_3) PF10385 (RNA_pol_Rpb2_6) PF00623 (RNA_pol_Rpb1_2) PF04983 (RNA_pol_Rpb1_3) PF04997 (RNA_pol_Rpb1_5) PF04998 (RNA_pol_Rpb1_4) PF05000 (RNA_pol_Rpb1_1)	18	ASP D 57 ARG D 84 LYS D 86 ARG D 89 GLU D 323 VAL D 328 ARG D 412 GLN D 415 LEU F 423 ASP F 424 MET C1051 ILE C1052 GLN C1054 THR C1096 VAL C1097 LYS C1101 GLU C1119 SER C1120	FI8 D1904

[["6BZO_C_FI8C1201","6bzo","FI8","DB08874(Fidaxomicin)","Mycobacterium tuberculosis","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA';RNA POLYMERASE SIGMA FACTOR SIGA;RNA POLYMERASE-BINDING PROTEIN RBPA","PF00140(Sigma70_r1_2);PF04539(Sigma70_r3);PF04542(Sigma70_r2);PF04545(Sigma70_r4);PF00562(RNA_pol_Rpb2_7);PF04560(RNA_pol_Rpb2_3);PF04561(RNA_pol_Rpb2_45);PF04565(RNA_pol_Rpb2_6);PF10385(RNA_pol_Rpb2_2);PF00623(RNA_pol_Rpb1_3);PF04983(RNA_pol_Rpb1_5);PF04997(RNA_pol_Rpb1_4);PF04998(RNA_pol_Rpb1_2);PF05000(RNA_pol_Rpb1_1);PF13397(RbpA)",28,"ARG J  10;VAL J  14;ARG D  84;LYS D  86;ARG D  89;GLU D 323;LEU D 324;PRO D 326;SER D 338;ARG D 412;GLN D 415;LEU F 423;ASP F 424;GLN F 434;VAL F 445;MET C1051;ILE C1052;THR C1053;GLN C1054;ASP C1094;THR C1096;VAL C1097;VAL C1100;LYS C1101;GLU C1119;SER C1120;VAL C1123;GLU C1127","FI8 C1201\r"],["6C06_D_FI8D1404","6c06","FI8","DB08874(Fidaxomicin)","Mycobacterium tuberculosis","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA';RNA POLYMERASE SIGMA FACTOR SIGA;RNA POLYMERASE-BINDING PROTEIN RBPA","PF00140(Sigma70_r1_2);PF04539(Sigma70_r3);PF04542(Sigma70_r2);PF04545(Sigma70_r4);PF00562(RNA_pol_Rpb2_7);PF04560(RNA_pol_Rpb2_3);PF04561(RNA_pol_Rpb2_45);PF04565(RNA_pol_Rpb2_6);PF10385(RNA_pol_Rpb2_2);PF00623(RNA_pol_Rpb1_3);PF04983(RNA_pol_Rpb1_2);PF04997(RNA_pol_Rpb1_4);PF04998(RNA_pol_Rpb1_5);PF05000(RNA_pol_Rpb1_1);PF13397(RbpA)",13,"ARG J  10;ARG D  84;LYS D  86;ARG D 412;GLN F 434;ILE C1052;THR C1053;GLN C1054;THR C1096;ARG C1099;LYS C1101;GLU C1119;SER C1120","FI8 D1404\r"],["6FBV_D_FI8D1904","6fbv","FI8","DB08874(Fidaxomicin)","Mycobacterium tuberculosis","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA';RNA POLYMERASE SIGMA FACTOR SIGA","PF00140(Sigma70_r1_2);PF00562(RNA_pol_Rpb2_45);PF04560(RNA_pol_Rpb2_7);PF04561(RNA_pol_Rpb2_2);PF04565(RNA_pol_Rpb2_3);PF10385(RNA_pol_Rpb2_6);PF00623(RNA_pol_Rpb1_2);PF04983(RNA_pol_Rpb1_3);PF04997(RNA_pol_Rpb1_5);PF04998(RNA_pol_Rpb1_4);PF05000(RNA_pol_Rpb1_1)",18,"ASP D  57;ARG D  84;LYS D  86;ARG D  89;GLU D 323;VAL D 328;ARG D 412;GLN D 415;LEU F 423;ASP F 424;MET C1051;ILE C1052;GLN C1054;THR C1096;VAL C1097;LYS C1101;GLU C1119;SER C1120","FI8 D1904\r"]]