DRUG BINDING INTERFACES MAPPED TO 'EVP'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
3QX3_A_EVPA1	3qx3	EVP DB00773 (Etoposide)	Homo sapiens	DNA TOPOISOMERASE 2-BETA	PF00521 (DNA_topoisoIV) PF01751 (Toprim) PF16898 (TOPRIM_C)	5	GLY A 478 ASP A 479 ARG A 503 GLN A 778 MET A 782	EVP A 1
3QX3_D_EVPD1	3qx3	EVP DB00773 (Etoposide)	; Homo sapiens	DNA TOPOISOMERASE 2-BETA	no annotation	5	GLY B 478 ASP B 479 ARG B 503 GLN B 778 MET B 782	EVP D 1
4LB9_A_EVPA605	4lb9	EVP DB00773 (Etoposide)	Homo sapiens	SERUM ALBUMIN	PF00273 (Serum_albumin)	10	ASP A 108 HIS A 146 TYR A 148 SER A 193 ARG A 197 CYS A 200 ALA A 201 GLN A 204 HIS A 247 GLY A 248	EVP A 605
5CDN_G_EVPG2101	5cdn	EVP DB00773 (Etoposide)	Staphylococcus aureus; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B	PF00521 (DNA_topoisoIV) PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	6	SER A 84 GLU A 88 GLY B 436 ASP B 437 ARG B 458 GLY B 459	EVP G2101
5CDN_N_EVPN2101	5cdn	EVP DB00773 (Etoposide)	Staphylococcus aureus; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B	no annotation	6	SER R 84 GLU R 88 GLY S 436 ASP S 437 ARG S 458 GLY S 459	EVP N2101
5CDN_O_EVPO2101	5cdn	EVP DB00773 (Etoposide)	Staphylococcus aureus; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B	no annotation	6	SER C 84 GLU C 88 GLY D 436 ASP D 437 ARG D 458 GLY D 459	EVP O2101
5CDN_P_EVPP2101	5cdn	EVP DB00773 (Etoposide)	Staphylococcus aureus; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B	no annotation	6	SER T 84 GLU T 88 GLY U 436 ASP U 437 ARG U 458 GLY U 459	EVP P2101
5CDP_H_EVPH2101	5cdp	EVP DB00773 (Etoposide)	Staphylococcus aureus; synthetic construct	DNA GYRASE SUBUNIT A; DNA GYRASE SUBUNIT B	PF00521 (DNA_topoisoIV) PF00986 (DNA_gyraseB_C) PF01751 (Toprim) no annotation	6	SER A 84 GLU A 88 GLY B 436 ASP B 437 ARG B 458 GLY B 459	EVP H2101
5GWK_D_EVPD102	5gwk	EVP DB00773 (Etoposide)	Homo sapiens; synthetic construct	DNA TOPOISOMERASE 2-ALPHA	no annotation	4	GLY B 462 ASP B 463 ARG B 487 MET B 766	EVP D 102
5GWK_F_EVPF102	5gwk	EVP DB00773 (Etoposide)	Homo sapiens; synthetic construct	DNA TOPOISOMERASE 2-ALPHA	PF00521 (DNA_topoisoIV) PF01751 (Toprim) PF16898 (TOPRIM_C) no annotation	5	GLY A 462 ASP A 463 ARG A 487 MET A 762 MET A 766	EVP F 102
5ZRF_D_EVPD101	5zrf	EVP DB00773 (Etoposide)			no annotation	5	GLY B 478 ASP B 479 ARG B 503 GLN B 778 MET B 782	EVP D 101
5ZRF_F_EVPF1301	5zrf	EVP DB00773 (Etoposide)			no annotation	4	GLY A 478 ASP A 479 ARG A 503 MET A 782	EVP F1301

[["3QX3_A_EVPA1","3qx3","EVP","DB00773(Etoposide)","Homo sapiens","DNA TOPOISOMERASE 2-BETA","PF00521(DNA_topoisoIV);PF01751(Toprim);PF16898(TOPRIM_C)",5,"GLY A 478;ASP A 479;ARG A 503;GLN A 778;MET A 782","EVP A   1\r"],["3QX3_D_EVPD1","3qx3","EVP","DB00773(Etoposide)",";Homo sapiens","DNA TOPOISOMERASE 2-BETA","no annotation",5,"GLY B 478;ASP B 479;ARG B 503;GLN B 778;MET B 782","EVP D   1\r"],["4LB9_A_EVPA605","4lb9","EVP","DB00773(Etoposide)","Homo sapiens","SERUM ALBUMIN","PF00273(Serum_albumin)",10,"ASP A 108;HIS A 146;TYR A 148;SER A 193;ARG A 197;CYS A 200;ALA A 201;GLN A 204;HIS A 247;GLY A 248","EVP A 605\r"],["5CDN_G_EVPG2101","5cdn","EVP","DB00773(Etoposide)","Staphylococcus aureus;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","PF00521(DNA_topoisoIV);PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",6,"SER A  84;GLU A  88;GLY B 436;ASP B 437;ARG B 458;GLY B 459","EVP G2101\r"],["5CDN_N_EVPN2101","5cdn","EVP","DB00773(Etoposide)","Staphylococcus aureus;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","no annotation",6,"SER R  84;GLU R  88;GLY S 436;ASP S 437;ARG S 458;GLY S 459","EVP N2101\r"],["5CDN_O_EVPO2101","5cdn","EVP","DB00773(Etoposide)","Staphylococcus aureus;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","no annotation",6,"SER C  84;GLU C  88;GLY D 436;ASP D 437;ARG D 458;GLY D 459","EVP O2101\r"],["5CDN_P_EVPP2101","5cdn","EVP","DB00773(Etoposide)","Staphylococcus aureus;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B,DNA GYRASE SUBUNIT B","no annotation",6,"SER T  84;GLU T  88;GLY U 436;ASP U 437;ARG U 458;GLY U 459","EVP P2101\r"],["5CDP_H_EVPH2101","5cdp","EVP","DB00773(Etoposide)","Staphylococcus aureus;synthetic construct","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B","PF00521(DNA_topoisoIV);PF00986(DNA_gyraseB_C);PF01751(Toprim);no annotation",6,"SER A  84;GLU A  88;GLY B 436;ASP B 437;ARG B 458;GLY B 459","EVP H2101\r"],["5GWK_D_EVPD102","5gwk","EVP","DB00773(Etoposide)","Homo sapiens;synthetic construct","DNA TOPOISOMERASE 2-ALPHA","no annotation",4,"GLY B 462;ASP B 463;ARG B 487;MET B 766","EVP D 102\r"],["5GWK_F_EVPF102","5gwk","EVP","DB00773(Etoposide)","Homo sapiens;synthetic construct","DNA TOPOISOMERASE 2-ALPHA","PF00521(DNA_topoisoIV);PF01751(Toprim);PF16898(TOPRIM_C);no annotation",5,"GLY A 462;ASP A 463;ARG A 487;MET A 762;MET A 766","EVP F 102\r"],["5ZRF_D_EVPD101","5zrf","EVP","DB00773(Etoposide)","","","no annotation",5,"GLY B 478;ASP B 479;ARG B 503;GLN B 778;MET B 782","EVP D 101\r"],["5ZRF_F_EVPF1301","5zrf","EVP","DB00773(Etoposide)","","","no annotation",4,"GLY A 478;ASP A 479;ARG A 503;MET A 782","EVP F1301\r"]]