DRUG BINDING INTERFACES MAPPED TO 'EFZ'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)

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DrReposER ID	PDB	Ligand	Organism	Macromolecule	Pfam	Res.	Interface	HETATM
1FK9_A_EFZA999	1fk9	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	HIV-1 RT, A-CHAIN	PF00075 (RNase_H) PF00078 (RVT_1) PF06815 (RVT_connect) PF06817 (RVT_thumb)	10	LEU A 100 LYS A 101 LYS A 103 VAL A 106 VAL A 179 TYR A 181 TYR A 188 GLY A 190 LEU A 234 TYR A 318	EFZ A 999
1FKO_A_EFZA999	1fko	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	HIV-1 RT, A-CHAIN	PF00075 (RNase_H) PF00078 (RVT_1) PF06815 (RVT_connect) PF06817 (RVT_thumb)	10	LEU A 100 ASN A 103 VAL A 106 VAL A 179 TYR A 181 TYR A 188 GLY A 190 TRP A 229 LEU A 234 TYR A 318	EFZ A 999
1IKV_A_EFZA2000	1ikv	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	POL POLYPROTEIN	PF00075 (RNase_H) PF00078 (RVT_1) PF06815 (RVT_connect) PF06817 (RVT_thumb)	9	LEU A 100 VAL A 106 VAL A 179 TYR A 181 TYR A 188 GLY A 190 TRP A 229 LEU A 234 TYR A 318	EFZ A2000
1IKW_A_EFZA2000	1ikw	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	POL POLYPROTEIN	PF00075 (RNase_H) PF00078 (RVT_1) PF06815 (RVT_connect) PF06817 (RVT_thumb)	10	LEU A 100 LYS A 103 VAL A 106 VAL A 179 TYR A 181 TYR A 188 GLY A 190 TRP A 229 LEU A 234 TYR A 318	EFZ A2000
1JKH_A_EFZA999	1jkh	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	HIV-1 RT, A-CHAIN; HIV-1 RT, B-CHAIN	PF00075 (RNase_H) PF00078 (RVT_1) PF06815 (RVT_connect) PF06817 (RVT_thumb)	11	LEU A 100 LYS A 103 VAL A 106 GLU B 138 VAL A 179 CYS A 181 TYR A 188 GLY A 190 TRP A 229 LEU A 234 TYR A 318	EFZ A 999
4B3O_A_EFZA1557	4b3o	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	REVERSE TRANSCRIPTASE/RIBONU CLEASE H	PF00075 (RNase_H) PF00078 (RVT_1) PF06815 (RVT_connect) PF06817 (RVT_thumb)	9	LEU A 100 LYS A 101 LYS A 103 VAL A 106 TYR A 181 TYR A 188 GLY A 190 LEU A 234 TYR A 318	EFZ A1557
6BSG_A_EFZA601	6bsg	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	REVERSE TRANSCRIPTASE P66 SUBUNIT	no annotation	10	LEU A 100 LYS A 103 VAL A 106 VAL A 179 TYR A 181 TYR A 188 GLY A 190 TRP A 229 LEU A 234 TYR A 318	EFZ A 601
6BSH_A_EFZA601	6bsh	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	REVERSE TRANSCRIPTASE P51 SUBUNIT; REVERSE TRANSCRIPTASE P66 SUBUNIT	no annotation	11	LEU A 100 LYS A 103 VAL A 106 GLU B 138 VAL A 179 TYR A 181 TYR A 188 GLY A 190 TRP A 229 LEU A 234 TYR A 318	EFZ A 601
6BSI_A_EFZA601	6bsi	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	REVERSE TRANSCRIPTASE P66 SUBUNIT	no annotation	10	LEU A 100 LYS A 103 VAL A 106 VAL A 179 TYR A 181 TYR A 188 GLY A 190 TRP A 229 LEU A 234 TYR A 318	EFZ A 601
6BSJ_A_EFZA601	6bsj	EFZ DB00625 (Efavirenz)	Human immunodeficienc y virus 1	REVERSE TRANSCRIPTASE P66 SUBUNIT	no annotation	10	LEU A 100 LYS A 103 VAL A 106 VAL A 179 TYR A 181 TYR A 188 GLY A 190 TRP A 229 LEU A 234 TYR A 318	EFZ A 601

[["1FK9_A_EFZA999","1fk9","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","HIV-1 RT, A-CHAIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"LEU A 100;LYS A 101;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;LEU A 234;TYR A 318","EFZ A 999\r"],["1FKO_A_EFZA999","1fko","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","HIV-1 RT, A-CHAIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"LEU A 100;ASN A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 999\r"],["1IKV_A_EFZA2000","1ikv","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","POL POLYPROTEIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",9,"LEU A 100;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A2000\r"],["1IKW_A_EFZA2000","1ikw","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","POL POLYPROTEIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A2000\r"],["1JKH_A_EFZA999","1jkh","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","HIV-1 RT, A-CHAIN;HIV-1 RT, B-CHAIN","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",11,"LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;CYS A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 999\r"],["4B3O_A_EFZA1557","4b3o","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","PF00075(RNase_H);PF00078(RVT_1);PF06815(RVT_connect);PF06817(RVT_thumb)",9,"LEU A 100;LYS A 101;LYS A 103;VAL A 106;TYR A 181;TYR A 188;GLY A 190;LEU A 234;TYR A 318","EFZ A1557\r"],["6BSG_A_EFZA601","6bsg","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE P66 SUBUNIT","no annotation",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 601\r"],["6BSH_A_EFZA601","6bsh","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE P51 SUBUNIT;REVERSE TRANSCRIPTASE P66 SUBUNIT","no annotation",11,"LEU A 100;LYS A 103;VAL A 106;GLU B 138;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 601\r"],["6BSI_A_EFZA601","6bsi","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE P66 SUBUNIT","no annotation",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 601\r"],["6BSJ_A_EFZA601","6bsj","EFZ","DB00625(Efavirenz)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE P66 SUBUNIT","no annotation",10,"LEU A 100;LYS A 103;VAL A 106;VAL A 179;TYR A 181;TYR A 188;GLY A 190;TRP A 229;LEU A 234;TYR A 318","EFZ A 601\r"]]